Patents by Inventor Eric Schopf

Eric Schopf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Automated purification and formulation device for radiopharmaceutical compounds
    Patent number: 10589250
    Abstract: A device for purifying and formulating a radiopharmaceutical compound includes an automated purification subsystem that automates the loading of a sample into a sample loop for downstream purification via HPLC. A column selector valve is provided to select from one of a plurality of columns. Fractions can be collected as well as the desired product. The device includes an automated formulation subsystem that first sends the product to a dilution reservoir prior to being pneumatically pushed onto a solid phase extraction (SPE) cartridge. Automated rinse, elution, and reconstitution are also performed with the automated formulation subsystem. The device may be directly coupled to the output of an automated radiosynthesizer.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: March 17, 2020
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SOFIE BIOSCIENCES, INC.
    Inventors: Eric Schopf, Melissa Moore, R. Michael van Dam, Brandon Maraglia, Alexander Hsiao
  • AUTOMATED PURIFICATION AND FORMULATION DEVICE FOR RADIOPHARMACEUTICAL COMPOUNDS
    Publication number: 20180065103
    Abstract: A device for purifying and formulating a radiopharmaceutical compound includes an automated purification subsystem that automates the loading of a sample into a sample loop for downstream purification via HPLC. A column selector valve is provided to select from one of a plurality of columns. Fractions can be collected as well as the desired product. The device includes an automated formulation subsystem that first sends the product to a dilution reservoir prior to being pneumatically pushed onto a solid phase extraction (SPE) cartridge. Automated rinse, elution, and reconstitution are also performed with the automated formulation subsystem. The device may be directly coupled to the output of an automated radiosynthesizer.
    Type: Application
    Filed: September 7, 2017
    Publication date: March 8, 2018
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SOFIE BIOSCIENCES, INC.
    Inventors: Eric Schopf, Melissa Moore, R. Michael van Dam, Brandon Maraglia, Alexander Hsiao
  • Polymeric nanocarriers with linear dual response mechanism
    Patent number: 9687553
    Abstract: Nanocarriers are synthesized with polymers that respond to lower pH and/or ROS by being degraded. The compositions may be utilized to selectively deliver payloads within patients by responding to lower pH and/or ROS at localities within the patient. The present invention also features methods of synthesizing nanocarriers that are degraded by lower pH and/or ROS.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: June 27, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Adah Almutairi, Jagadis Sankaranarayanan, Enas Mahmoud, Eric Schopf
  • POLYMERIC NANOCARRIERS WITH LINEAR DUAL RESPONSE MECHANISM
    Publication number: 20150079005
    Abstract: Nanocarriers are synthesized with polymers that respond to lower pH and/or ROS by being degraded. The compositions may be utilized to selectively deliver payloads within patients by responding to lower pH and/or ROS at localities within the patient. The present invention also features methods of synthesizing nanocarriers that are degraded by lower pH and/or ROS.
    Type: Application
    Filed: May 7, 2014
    Publication date: March 19, 2015
    Applicant: The Regents of the University of California
    Inventors: Adah Almutairi, Jagadis Sankaranarayanan, Enas Mahmoud, Eric Schopf
  • Polymeric nano-carriers with a linear dual response mechanism and uses thereof
    Patent number: 8758778
    Abstract: The present invention features compositions in which nano-carriers are synthesized with polymers that respond to lower pH and/or ROS by being degraded. The compositions may be utilized to selectively deliver payloads within patients by responding to lower pH and/or ROS at localities within the patient. The present invention also features methods of synthesizing nano-carriers that are degraded by lower pH and/or ROS.
    Type: Grant
    Filed: September 16, 2011
    Date of Patent: June 24, 2014
    Assignee: The Regents of the University of California
    Inventors: Adah Almutairi, Jagadis Sankaranarayanan, Enas Mahmoud, Eric Schopf
  • POLYMERIC NANO-CARRIERS WITH A LINEAR DUAL RESPONSE MECHANISM AND USES THEREOF
    Publication number: 20120070383
    Abstract: The present invention features compositions in which nano-carriers are synthesized with polymers that respond to lower pH and/or ROS by being degraded. The compositions may be utilized to selectively deliver payloads within patients by responding to lower pH and/or ROS at localities within the patient. The present invention also features methods of synthesizing nano-carriers that are degraded by lower pH and/or ROS.
    Type: Application
    Filed: September 16, 2011
    Publication date: March 22, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Adah Almutairi, Jagadis Sankaranarayanan, Enas Mahmoud, Eric Schopf