Abstract: According to an example, machine readable instructions backward compatibility may include determining changes between first and second sets of machine readable instructions, and generating a backward compatibility switch. The backward compatibility switch may be implemented in the second set of machine readable instructions to selectively revert functionality to functionality of the first set of machine readable instructions.

Abstract: Methods are provided for reducing the number of aldehyde adducts and/or crosslinks from fixed biomolecules. In some cases, subject methods include contacting a sample having aldehyde fixed biomolecules (e.g., a biological sample such as a formalin fixed paraffin embedded (FFPE) tissue sample) with an adduct reversal agent in an amount and for a period of time sufficient to reduce the number of aldehyde fixation related adducts and/or crosslinks in the sample. In some cases, the adduct reversal agent is a compound that includes an aromatic ring and at least one of: an amine group and a proton-donating group. In some cases, the adduct reversal agent is a compound selected from the compounds of Table 1. Compositions and kits for practicing the subject methods are also provided.

Abstract: A connector assembly is provided for coupling optical fibers to a spectrometer. The connector assembly includes a plate having a slit defined therein and a ferrule that secures end portions of the optical fibers therein. The ferrule includes a forward end having an aperture that receives the optical fibers. The connector assembly further includes a connector housing having an alignment mechanism with a plate recess dimensioned to receive the plate therein and a ferrule recess dimensioned to receive the forward end of the ferrule therein. The plate recess orients the plate and the ferrule recess orients the ferrule within the connector assembly that includes a spring for imparting a force urging the forward end of the ferrule into contact with the plate to minimize an air gap between the plate and the ferrule. The spring and the alignment mechanism maintain the ferrule in an x-y-z, rotation, and/or an angular orientation.

Abstract: A connector assembly is provided for coupling optical fibers to a spectrometer. The connector assembly includes a plate having a slit defined therein and a ferrule that secures end portions of the optical fibers therein. The ferrule includes a forward end having an aperture that receives the optical fibers. The connector assembly further includes a connector housing having an alignment mechanism with a plate recess dimensioned to receive the plate therein and a ferrule recess dimensioned to receive the forward end of the ferrule therein. The plate recess orients the plate and the ferrule recess orients the ferrule within the connector assembly that includes a spring for imparting a force urging the forward end of the ferrule into contact with the plate to minimize an air gap between the plate and the ferrule. The spring and the alignment mechanism maintain the ferrule in an x-y-z, rotation, and/or an angular orientation.

Abstract: Systems and methods are disclosed for collecting vehicle data from a vehicle engine computer of a vehicle and a plurality of sensors disposed about the vehicle and generating feedbacks for a driver of the vehicle using at least the vehicle data. The systems and methods additionally provide for receiving user inputs from the driver responding to the feedbacks so that the user inputs are associated with corresponding rule violations that triggered the feedbacks.

Abstract: One embodiment provides a method, comprising: receiving, from a client device, a request by a user to access an aggregate service device; authenticating, at an aggregate service device, the user to provide access to a plurality of cloud storage accounts of the user hosted by a single cloud storage service; providing, by the aggregate service device, data analogous to data of the plurality of cloud storage accounts; receiving, by the aggregate service device, a selection of data accessible by the user from the plurality of cloud storage accounts of the user; and facilitating data transfer associated with the selection.

Abstract: Systems and methods are disclosed for collecting vehicle data from a vehicle engine computer of a vehicle and a plurality of sensors disposed about the vehicle and generating feedbacks for a driver of the vehicle using at least the vehicle data. One or more validation checks may be performed before the feedbacks are provided to the driver.

Abstract: A user interface for presenting a set of related pages of an electronic content work for view at the same time. The pages are sized according to a target format for presentation of the electronic content work, and may also be formatted according to user-defined font and zoom criteria. Each of the related pages comprises a media object, for example a markup language object. Responsive to user manipulation of presentation criterion for the set of related pages, the set of related pages is reformatted and so presented in near real-time. In some instances, a user may manipulate controls of the user interface to isolate a content object included within the set of related pages, have information regarding that content object presented and even edit the content object in-line with the present view.

Abstract: Computer tools, processes, and systems for capturing web content are provided. A webpage is rendered on a user device. An area within the rendered webpage is selected. Metadata describing the location of the web content within the selected area of the rendered webpage is determined and persistently stored within a database. A window is provided on a user device rendering the web content corresponding to the selected area. The web content is rendered within the window in the same context as the web content was initially rendered on the user device. The rendered web content may include partial objects or elements of the web page and provide all the functionality normally associated with the web content. The web content may be shared with other users including sending a message with a link configured to render the web content corresponding to the selected area on a user device.

Abstract: Methods for obtaining structural data from RNA in a sample, and RNA probes for performing the same, are provided. Methods of reversibly modifying RNA is a sample, in vitro or in vivo, and reversible probes for performing the same, are provided. The RNA probes may be SHAPE probes that include aryl or heteroaryl acyl imidazoles. The RNA probes may be reversible probes that include an aryl or heteroaryl ring substituted with a hydroxyl-reactive group and an azido-containing group. Also provided are methods of comparing in vitro and in vivo RNA structural data. Also provided are methods of diagnosing a cellular proliferative disease condition, e.g., by probing HOTAIR RNA. Aspects of the invention further include compositions, e.g., probes and kits, etc., that find use in methods of the invention.

Abstract: Systems and methods are disclosed for collecting vehicle data from a vehicle engine computer of a vehicle and a plurality of sensors disposed about the vehicle and generating feedbacks for a driver of the vehicle using at least the vehicle data. The systems and methods additionally provide for receiving user inputs from the driver responding to the feedbacks so that the user inputs are associated with corresponding rule violations that triggered the feedbacks.

Abstract: Probes comprising one or more selectively cleavable ?-azidoether moieties are provided; and linkers comprising the one or more selectively cleavable ?-azidoether moieties. The ?-azidoether moiety will undergo a Staudinger reaction with a suitable reducing agent, resulting in cleavage. The probes find use in a variety of detection assays, e.g. specific polynucleotide binding assays, polypeptide binding assays, etc. The cleavable linkers are suitable for synthetic reactions, e.g. to prepare probes of the invention; in the synthesis of cleavable peptide conjugates; and the like.

Abstract: Nucleoside analogs are provided; and fluorescent sensors comprising the nucleoside analogs. The sensors comprise multiple chromophores built on a DNA backbone, in which all the natural DNA bases are replaced by excimeric or exciplex-forming fluorophores, ligands, quenchers and spacers in thousands of combinations. The sensors find use in the detection and identification of target analytes by fluorescence, e.g., detection of metal ions, neutral organic compounds and anions. The sensors find use in the detection and identification of molecular species in the vapor or gaseous phase, or the liquid phase. The sensors find use in qualitative and quantitative screening and detection methods.

Abstract: An exercise data collection system for use with an exercise machine, including a computerized processing unit and at least two sensors mounted on or near the exercise machine to capture data indicative of aspects of exercising performed by a user of the exercise machine. A first of the at least two sensors being of a first sensor type and a second of the at least two sensors being of a second sensor type different from the first sensor type. The sensors including circuitry associated therewith sufficient to allow the sensors to wirelessly communicate captured data for receipt and analysis by the processing unit, which includes programming that will cause the processing unit to analyze the received captured data in conjunction with characteristics of the user so that a representation of the exercise performed by the user can be constructed that reflects the exercising as it was performed by the user.

Abstract: One embodiment provides a method, comprising: receiving, from a client device, a request by a user to access an aggregate service device; authenticating, at an aggregate service device, the user to provide access to a plurality of cloud storage accounts of the user hosted by a single cloud storage service; providing, by the aggregate service device, data analogous to data of the plurality of cloud storage accounts; receiving, by the aggregate service device, a selection of data accessible by the user from the plurality of cloud storage accounts of the user; and facilitating data transfer associated with the selection.

Abstract: One embodiment provides a method, including: receiving authentication input, at a device, that is sent to an aggregate service device; requesting file system data, retrieved by the aggregate service device, analogous to data stored on a remote device and data stored on a cloud storage device; receiving at the device, after providing the authentication input to the aggregate service device, the file system data from the aggregate service device; and displaying, on the device, a user interface in the form of a file manager application generated from the requested file system data.

Abstract: One embodiment provides a method, including: sending, from a device, input from a user requesting access to data retrievable by an aggregate service device; sending, from the device, input from the user selecting, from the aggregate service device, a selection of data; and sending a distribution command; wherein the distribution command comprises information related to distributing a pointer indicating the selection of data.

Abstract: One embodiment provides a method, involving receiving, at a device, input from a user; requesting, using the input, access to an aggregate service device having access to data stored on at least one non-local user device; receiving, at the device, search criteria from the user; receiving results produced by searching the data stored on at least one non-local user device utilizing the search criteria; and displaying, at the device, the results of the searching.

Abstract: Systems and methods are disclosed for collecting vehicle data from a vehicle engine computer of a vehicle and a plurality of sensors disposed about the vehicle and generating feedbacks for a driver of the vehicle using at least the vehicle data. The systems and methods additionally provide for receiving user inputs from the driver responding to the feedbacks so that the user inputs are associated with corresponding rule violations that triggered the feedbacks.

Abstract: A reconfigurable modular lighting assembly, including at least two tube sections, each tube section having an end cap thereon and including at least one light emitting diode light source. An interconnection unit including multiple tube section receiving locations that each physically, releasably connect one end of a first of the at least two tube sections to one end of a second of the at least two tube sections such that the tube sections are adjacent and form a positive angle between them; and provide for interchangeably electrically connecting the light sources in the tube sections to a source of electrical power. Control data paths are operatively connected to each of the light emitting diode light sources via the interconnection unit to allow for control of the light emitting diode light sources when the at least two tube sections are respectively connected to the interconnection unit at the tube section receiving locations.