Abstract: A vertical-cavity surface-emitting laser (VCSEL) array may include an n-type substrate layer and an n-type metal on a bottom surface of the n-type substrate layer. The n-type metal may form a common anode for a group of VCSEL. The VCSEL array may include a bottom mirror structure on a top surface of the n-type substrate layer. The bottom mirror structure may include one or more bottom mirror sections and a tunnel junction to reverse a carrier type within the bottom mirror structure. The VCSEL array may include an active region on the bottom mirror structure and an oxidation layer to provide optical and electrical confinement. The VCSEL array may include an n-type top mirror on the active region, a top contact layer over the n-type top mirror, and a top metal on the top contact layer. The top metal may form an isolated cathode for the VCSEL array.

Abstract: The disclosure provides technology for enhancing the ability of a computing device to detect when a user has discontinued reading a text source. An example method includes receiving audio data comprising a spoken word associated with a text source, comparing the audio data with data of the text source, determining, based on the comparing, whether a segment of the audio data corresponds to a location of the text source, and responsive to determining that the segment of the audio data does not correspond to a location of the text source, transmitting a signal indicating that a user has discontinued reading the text source, the signal causing to cease the comparing of the audio data with the data of the text source.

Abstract: Antigen binding molecules (ABMs) comprising Fab domains in non-native configurations, ABM conjugates comprising the ABMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the ABMs and ABM conjugates, methods of using the ABMs, ABM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the ABMs, cells engineered to express the ABMs, and methods of producing ABMs.

Abstract: The disclosure relates to a 5G or 6G communication system for supporting a higher data transmission rate. Methods and apparatuses in provided in which a session description protocol (SDP) offer including a list of artificial intelligence (AI) models is received from a media resource function (MRF) entity. At least one AI model is identified from the list for outputting at least one result using first media data, based on a type of the first media data and a media service in which the at least one result is used. An SDP response is transmitted to the MRF entity, requesting the at least one AI model as a response to the SDP offer, and the first media data is processed based on the at least one AI model received from the MRF entity.

Abstract: This disclosure provides systems, devices, apparatus, and methods, including computer programs encoded on storage media, for dynamic wave pairing. A graphics processor may allocate one or more GPU workloads to one or more wave slots of a plurality of wave slots. The graphics processor may select a first execution slot of a plurality of execution slots for executing the one or more GPU workloads. The selection may be based on one of a plurality of granularities. The graphics processor may execute, at the selected first execution slot, the one or more GPU workloads at the one of the plurality of granularities.

Abstract: The present invention provides multispecific antigen-binding molecules that bind both a T-cell antigen (e.g., CD3) and a target antigen (e.g., a tumor associated antigen, a viral or bacterial antigen), and which include a single polypeptide chain that is multivalent (e.g., bivalent) with respect to T-cell antigen binding, and uses thereof.

Abstract: A method of using a catheter assembly for inserting in a fluid filled space in a body includes providing a main body having a first end portion and a second end portion. The first end portion is positioned within the fluid filled space. The second end portion is adjusted to extend outwardly from the fluid filled space when the first end portion is positioned within the fluid filled space. A catheter tip is connected to the second end portion of the main body. The catheter tip includes a housing having a cavity defined therein and a rotating element positioned within the fluid filled space. The rotating element is rotated within the cavity of the housing to impart movement of the first end portion of the main body within the fluid filled space.

Abstract: The present disclosure provides interferon receptor agonists with improved safety profiles and therapeutic indices. The interferon receptor agonists are attenuated through masking and/or reduced receptor binding as compared to a wild-type interferon. IFN receptor agonists optionally further comprise a targeting moiety, e.g., a targeting moiety that recognizes a tumor- or immune cell-associated antigen and directs the interferon receptor agonist to a tumor site and/or tumor-reactive immune cells. The disclosure further provides pharmaceutical compositions comprising the interferon receptor agonists, and methods of use of the interferon receptor agonists in therapy, as well as nucleic acids encoding the interferon receptor agonists, recombinant cells that express the interferon receptor agonists and methods of producing the interferon receptor agonists.

Abstract: Aspects of the technology described herein relate to improved semiconductor-based image sensor designs. In some embodiments, an integrated circuit may comprise a photodetection region and a drain region electrically coupled to the photodetection region, and the photodetection region may be configured to induce an intrinsic electric field in a direction from the photodetection region to the drain region(s). In some embodiments, a charge storage region and the drain region may be positioned on a same side of the photodetection region. In some embodiments, at least one drain layer may be configured to receive incident photons and/or charge carriers via the photodetection region. In some embodiments, an integrated circuit may comprise a plurality of pixels and a control circuit configured to control a transfer of charge carriers in the plurality of pixels.

Abstract: A method performed by a first terminal is provided. The method includes identifying capabilities of the first terminal connected to at least one component device, establishing, via a server, a session associated with an augmented reality (AR) service based on the capabilities of the first terminal, performing pre-processing on 3 dimensional (3D) media data acquired by the at least one component device, and transmitting, to a second terminal, the pre-processed 3D media data.

Abstract: The present disclosure provides interferon receptor agonists with improved safety profiles and therapeutic indices. The interferon receptor agonists are attenuated through masking and/or reduced receptor binding as compared to a wild-type interferon. IFN receptor agonists optionally further comprise a targeting moiety, e.g., a targeting moiety that recognizes a tumor- or immune cell-associated antigen and directs the interferon receptor agonist to a tumor site and/or tumor-reactive immune cells. The disclosure further provides pharmaceutical compositions comprising the interferon receptor agonists, and methods of use of the interferon receptor agonists in therapy, as well as nucleic acids encoding the interferon receptor agonists, recombinant cells that express the interferon receptor agonists and methods of producing the interferon receptor agonists.

Abstract: The present invention relates to a method for preventing transmission of influenza, wherein said method comprises administering an effective amount of a compound to a patient having an influenza virus infection, herein referred to as “index patient”, wherein the compound has one of the formulae (I) and (II), or its pharmaceutically acceptable salt. The compound to be used in the present invention reduces infectivity of the influenza virus of the index patient, and therefore, reduces the risk of the index patient to trigger an influenza epidemic or an influenza pandemic as compared to a control patient.

Abstract: A product-display system for displaying and securing a retail product. The system may include a retainer having a retainer bracket and a retainer body coupled to the retainer bracket. A retaining cable may be coupled to the retainer body at an opening in the retainer body. A fastener that may be unfastened to release the product from the retainer may only be accessed through the opening of the retainer body such that when the retaining cable is coupled to the opening, no fasteners of the retainer may be visible or accessible. The system may also include a display stem for holding the retainer and product. The display stem may include a recess for receiving at least a portion of the retainer body. The retaining cable may extend through the display stem and may simultaneously transmit power and data to a displayed product. The retainer may be returned to and held on top of the display stem using a retaining cable.

Abstract: Fluorided silica-coated alumina activator-supports have a bulk density from 0.15 to g/mL, a total pore volume from 0.85 to 2 mL/g, a BET surface area from 200 to 500 m2/g, an average pore diameter from 10 to 25 nm, and from 80 to 99% of pore volume in pores with diameters of greater than 6 nm. Methods of making the fluorided silica-coated alumina activator-supports and using the fluorided silica-coated aluminas in catalyst compositions and olefin polymerization processes also are described. Representative ethylene-based polymers produced using the compositions and processes have a melt index of 0.1 to 10 g/10 min and a density of 0.91 to 0.96 g/cm3, and contain from 70 to 270 ppm solid oxide and from 2 to 18 ppm fluorine.

Abstract: In various examples, a cell model that partitions a geographic region into one or more cells is used to determine clusters of cell which share similarities. Sensor data is provided to one or more machine learning models trained to classify the sensor data to one or more cells of the cell model. Based on classifying sensor data to cells of a cell model, similarities between pairings of cells of the cell model may be determined and used to form clusters of the cell which are sufficiently similar in order to aid in the curation of training data used to train machine learning models in order to aid an autonomous or semi-autonomous machine in a surrounding environment.

Abstract: Apparatuses for dynamically sensing infrared (IR) radiation in an electron beam powder bed fusion (EB-PBF) printer are provided. A radiation collector receives radiation from a surface of the powder bed. An IR-transparent material rejects one or more non-IR wavelengths, and a lens focuses the IR radiation onto an optical fiber. The IR radiation is carried from the vacuum chamber of the printer to a sensor, where IR information is determined based on the received IR radiation. The IR information may be received from the sensor and used by the print controller to modify one or more parameters, such as beam intensity or scanning rate, on the fly or during the next print cycle. An occlusion member can be used to selectively block or expose the radiation collector to protect the radiation collector from condensation of vapor from vaporization of particles at high temperatures.

Abstract: In various aspects, 3D printers and recoaters incorporate sensor systems coupled to or integrated with the 3D printers. The sensor systems may include eddy current sensors and other sensors configured to measure an electromagnetic characteristic of the build piece. A three-dimensional (3-D) printer in one aspect includes a depositor configured to deposit metal, an energy beam source configured to selectively melt the metal to form a portion of a build piece, and a sensor configured to move relative to a surface of the print area and to measure an electromagnetic characteristic of the portion of the print area. The measured data can be used to detect defects and other information about the build piece that can be used to fix the defects or enhance the build piece geometry during the printing.

Abstract: In various aspects, 3D printers, and sensor systems coupled to or integrated with the 3D printers are disclosed. The sensor systems may include image and second sensors for detecting potential defects or print artifacts. During printing, an energy beam source forms a weld pool by melting selected regions of print material, which solidifies to produce the build piece. The image sensor may image an area including the weld pool to determine a landing location of matter ejected during the heating of print material to form the weld pool. The second sensor may detect a defect in the build piece based on the determination of the landing location. Print operation may be suspended while the sensor data is used to repair the defect, after which 3D printing resumes. In this way, for example, high quality build pieces can be produced with reduced post-processing times, and hence a higher manufacturing throughput.

Abstract: A radiant area heater includes a columnar base with a hollow compartment and a heating column disposed on the columnar base. The heating column includes a control portion with at least one controller, a burner, and a sparker and a flame portion that includes a combustion chamber. The combustion chamber is disposed on a cylindrical member that has at least one vent allowing air to circulate to the burner and within the combustion chamber. The heating column further includes at least one heat emitting screen disposed above the flame portion that radiates heat outwards from the heater. A cover is disposed over the heating column to direct heat outwards and away from the heater.

Abstract: A direct AC to AC converter includes a modulation stage, a transformer and a de-modulation stage. The modulation stage is configured to convert an AC input voltage with a first frequency into a bipolar PWM voltage with a second frequency, wherein the second frequency is higher than the first frequency. The transformer has a primary winding and secondary winding, wherein the primary winding is coupled to the modulation stage to receive the bipolar PWM voltage. The de-modulation stage is coupled to the secondary winding of the transformer and configured to convert the voltage across the secondary winding of the transformer into an AC output voltage with the first frequency.