Patents by Inventor Erica M.W. Lauterwasser

Erica M.W. Lauterwasser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220017559
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5] decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 22, 2021
    Publication date: January 20, 2022
    Inventors: Adam R. Renslo, Erica M.W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • Patent number: 11014955
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5] decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: May 25, 2021
    Assignee: The Regents of the University of California
    Inventors: Adam R. Renslo, Erica M. W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • Publication number: 20200317714
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5] decane. Also disclosed is a pharmaceutical composition containing the compound and a phannaceutically acceptable carrier.
    Type: Application
    Filed: April 8, 2020
    Publication date: October 8, 2020
    Inventors: Adam R. Renslo, Erica M.W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • Patent number: 10662215
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: May 26, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Adam R. Renslo, Erica M. W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • Patent number: 10604493
    Abstract: Embodiments of the present disclosure, in one aspect, relate to a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: March 31, 2020
    Assignees: University of South Florida, The Regents of the University of California
    Inventors: Yu Chen, Derek Nichols, Adam R. Renslo, Priyadarshini Jaishankar, Erica M. W. Lauterwasser
  • Publication number: 20190284224
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: March 26, 2019
    Publication date: September 19, 2019
    Inventors: Adam R. Renslo, Erica M.W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • Patent number: 10287312
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: May 14, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Adam R. Renslo, Erica M. W. Lauterwasser, Shaun D. Fontaine, Benjamin B. Spangler, James A. Wells
  • Publication number: 20170088524
    Abstract: Embodiments of the present disclosure, in one aspect, relate to a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Application
    Filed: November 8, 2016
    Publication date: March 30, 2017
    Inventors: Yu Chen, Derek Nichols, Adam R. Renslo, Priyadarshini Jaishankar, Erica M. W. Lauterwasser
  • Patent number: 9556131
    Abstract: Embodiments of the present disclosure, in one aspect, relate to a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: January 31, 2017
    Assignees: UNIVERSITY OF SOUTH FLORIDA, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Yu Chen, Derek Nichols, Adam R. Renslo, Priyadarshini Jaishankar, Erica M. W. Lauterwasser
  • Publication number: 20160362439
    Abstract: Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: February 13, 2015
    Publication date: December 15, 2016
    Inventors: Adam R. RENSLO, Erica M.W. LAUTERWASSER, Shaun D. FONTAINE, Benjamin B. SPANGLER, James A. WELLS
  • Publication number: 20140378516
    Abstract: Embodiments of the present disclosure, in one aspect, relate to a beta-lactamase inhibitor, pharmaceutical compositions including a beta-lactamase inhibitor, methods of treatment of a condition (e.g., infection) or disease, methods of treatment using compositions or pharmaceutical compositions, and the like.
    Type: Application
    Filed: January 4, 2013
    Publication date: December 25, 2014
    Inventors: Yu Chen, Derek Nichols, Adam R. Renslo, Priyadarshini Jaishankar, Erica M.W. Lauterwasser