Patents by Inventor Erick T. Tatro

Erick T. Tatro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for arranging and packing nucleic acids for unusual resistance to nucleases and targeted delivery for gene therapy
    Patent number: 10046057
    Abstract: There are disclosed compositions and methods to render nucleic acids resistant to nuclease digestion while maintaining sequence selective hybridization competency. The approach relies on utilizing nucleic acids as the polar head group of a nucleic acid-polymer amphiphile in order to assemble well-defined, discrete micellar nanoparticles. Dense packing of nucleic acid in the micelle corona allows for hybridization of complementary oligonucleotides while prohibiting enzymatic degradation.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: August 14, 2018
    Assignee: The Regents of the University of California
    Inventors: Erick T. Tatro, Nathan Gianneschi, Anthony M. Rush
  • METHODS FOR ARRANGING AND PACKING NUCLEIC ACIDS FOR UNUSUAL RESISTANCE TO NUCLEASES AND TARGETED DELIVERY FOR GENE THERAPY
    Publication number: 20150190525
    Abstract: There are disclosed compositions and methods to render nucleic acids resistant to nuclease digestion while maintaining sequence selective hybridization competency. The approach relies on utilizing nucleic acids as the polar head group of a nucleic acid-polymer amphiphile in order to assemble well-defined, discrete micellar nanoparticles. Dense packing of nucleic acid in the micelle corona allows for hybridization of complementary oligonucleotides while prohibiting enzymatic degradation.
    Type: Application
    Filed: March 24, 2015
    Publication date: July 9, 2015
    Inventors: Erick T. Tatro, Nathan Gianneschi, Anthony M. Rush