Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: Flat electric heater element having a self-adhesive surface for the purpose of adhesive-bonding to a glass pane of a motor vehicle, and having a passage opening to allow the passage of signals from/to a signaling device which is installed in the motor vehicle.

Abstract: A device for preparing and dispensing a drink comprises a dosing device (21,22) for a product to be mixed with a liquid in a mixing chamber (50), wherein the drink prepared therefrom can be drawn off at an outlet (60). The dosing device (21,22) is provided with a placing space for an exchangeable product holder (31,32), an outflow opening of which is at least initially provided with a removable seal (33 . . . 35). The seal comprises a foil folded back on itself, a base part (33) of which is attached to an edge (37,38) of the product holder (31,32) and a folded further part (34) of which leads back to a front side and protrudes with a pulling part (35) out of the placing space. At least the folded part (34) of the foil is laterally movable inside the placing space in order to allow removal of the foil from a placed product holder.

Abstract: Flat electric heater element having a self-adhesive surface for the purpose of adhesive-bonding to a glass pane of a motor vehicle, and having a passage opening to allow the passage of signals from/to a signaling device which is installed in the motor vehicle.

Abstract: The present invention is directed to a system for reducing condensation on the inner surface of a vehicle light cover, and preventing or deicing ice build up on the exterior of the cover. In an embodiment, a heater is mounted to a carrier and the heat produced by the heater prevents the occurrence of condensation on the inner surface of the light cover or build up of ice on the outer surface. In an embodiment, one or more vents may be provided in the carrier and one or more corresponding holes may be provided in the heater so as to increase the flow of air across the inner surface of the light cover. A controller may be provided to control activation of the heater.

Abstract: A power distribution system is provided for an automobile mirror assembly or the like, and includes a flexible membrane having electrical traces electrically connected to the vehicle electrical system, and connecting sites for electrically connecting to various power consumers in the mirror assembly.

Abstract: The present invention is directed to a system for reducing condensation on the inner surface of a vehicle light cover, and preventing or deicing ice build up on the exterior of the cover. In an embodiment, a heater is mounted to a carrier and the heat produced by the heater prevents the occurrence of condensation on the inner surface of the light cover or build up of ice on the outer surface. In an embodiment, one or more vents may be provided in the carrier and one or more corresponding holes may be provided in the heater so as to increase the flow of air across the inner surface of the light cover. A controller may be provided to control activation of the heater.

Abstract: A power distribution system is provided for an automobile mirror assembly or the like, and includes a flexible membrane having electrical traces electrically connected to the vehicle electrical system, and connecting sites for electrically connecting to various power consumers in the mirror assembly.

Abstract: A tree felling device comprising a spherical bowl carrying an endless saw chain along its peripheral edge and mounted to be moved a limited angle around the center of an imagined sphere in which it is included.