Patents by Inventor Erik J. Severin

Erik J. Severin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6571603
    Abstract: A statistical metric, based on the magnitude and standard deviations along linear projections of clustered array response data, is utilized to facilitate an evaluation of the performance of detector arrays in various vapor classification tasks. This approach allows quantification of the ability of arrays of different types including carbon black-insulating polymer composite chemiresistor sensors, tin oxide sensors and bulk conducting organic polymer sensors to distinguish between analytes. The evaluation of questions such as the optimal number of detectors required for a specific task, whether improved performance is obtained by increasing the number of detectors in a detector array, and how to assess statistically the diversity of a collection of detectors in order to understand more fully which properties are underrepresented in a particular set of array elements, are addressed.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: June 3, 2003
    Assignee: California Institute of Technology
    Inventors: Brett J. Doleman, Erik J. Severin, Nathan S. Lewis
  • Patent number: 6537498
    Abstract: Chemical sensors for detecting analytes in fluids comprising a plurality of alternating nonconductive regions (comprising a nonconductive material) and conductive regions (comprising a conductive material). In preferred embodiments, the conducting region comprises a nanoparticle. Variability in chemical sensitivity from sensor to sensor is provided by qualitatively or quantitatively varying the composition of the conductive and/or nonconductive regions. An electronic nose for detecting an analyte in a fluid may be constructed by using such arrays in conjunction with an electrical measuring device electrically connected to the conductive elements of each sensor.
    Type: Grant
    Filed: June 8, 1999
    Date of Patent: March 25, 2003
    Assignee: California Institute of Technology
    Inventors: Nathan S. Lewis, Brett J. Doleman, Shawn Briglin, Erik J. Severin
  • Publication number: 20020197390
    Abstract: Chemical sensors for detecting the activity of a molecule or analyte of interest is provided. The chemical sensors comprise and array or plurality of sensors that are capable of interacting with a molecule of interest, wherein the interaction provides a response fingerprint. The fingerprint can be associated with a library of similar molecules of interest to determine the molecule's activity and diffusion coefficient.
    Type: Application
    Filed: July 20, 2001
    Publication date: December 26, 2002
    Inventors: Nathan S. Lewis, Erik J. Severin, Michael Freund, Adam J. Matzger
  • Patent number: 6467333
    Abstract: The present invention provides a device for detecting the presence of an analyte, such as for example, a lightweight device, including: a sample chamber having a fluid inlet port for the influx of the analyte; a fluid concentrator in flow communication with the sample chamber wherein the fluid concentrator has an absorbent material capable of absorbing the analyte and capable of desorbing a concentrated analyte; and an array of sensors in fluid communication with the concentrated analyte to be released from the fluid concentrator.
    Type: Grant
    Filed: March 22, 2001
    Date of Patent: October 22, 2002
    Assignee: California Institute of Technology
    Inventors: Nathan S. Lewis, Erik J. Severin, Bernard Wong
  • Publication number: 20020141901
    Abstract: Chemical sensors for detecting the activity of a molecule or analyte of interest is provided. The chemical sensors comprise and array or plurality of sensors that are capable of interacting with a molecule of interest, wherein the interaction provides a response fingerprint. The fingerprint can be associated with a library of similar molecules of interest to determine the molecule's activity and diffusion coefficient.
    Type: Application
    Filed: July 20, 2001
    Publication date: October 3, 2002
    Inventors: Nathan S. Lewis, Erik J. Severin, Michael Freund, Adam J. Matzger
  • Patent number: 6387329
    Abstract: Chemical sensors for detecting the activity of a molecule or analyte of interest is provided. The chemical sensors comprise and array or plurality of sensors that are capable of interacting with a molecule of interest, wherein the interaction provides a response fingerprint. The fingerprint can be associated with a library of similar molecules of interest to determine the molecule's activity and diffusion coefficient.
    Type: Grant
    Filed: November 16, 1999
    Date of Patent: May 14, 2002
    Assignee: California Institute of Technology
    Inventors: Nathan S. Lewis, Erik J. Severin, Michael Freund, Adam J. Matzger
  • Publication number: 20020017125
    Abstract: The present invention provides a device for detecting the presence of an analyte, including: a sample chamber having a fluid inlet port for the influx of the analyte; a fluid concentrator in flow communication with the sample chamber wherein the fluid concentrator has an absorbent material capable of absorbing the analyte and capable of desorbing a concentrated analyte; and an array of sensors in fluid communication with the concentrated analyte.
    Type: Application
    Filed: March 23, 2001
    Publication date: February 14, 2002
    Inventors: Nathan S. Lewis, Erik J. Severin, Bernard Wong
  • Patent number: 6319724
    Abstract: The present invention provides methods for detecting the presence of an analyte indicative of various medical conditions, including halitosis, periodontal disease and other diseases are also disclosed.
    Type: Grant
    Filed: June 17, 1999
    Date of Patent: November 20, 2001
    Assignees: Cyrano Sciences, Inc., California Institute of Technology
    Inventors: Nathan S. Lewis, Erik J. Severin, Bernard Wong, David M. Kelso, Beth C. Munoz
  • Patent number: 6244096
    Abstract: The present invention provides a device for detecting the presence of an analyte, wherein said analyte is a microorganism marker gas. The device comprises a sample chamber having a fluid inlet port for the influx of the microorganism marker gas; a fluid concentrator in flow communication with the sample chamber, wherein the fluid concentrator has an absorbent material capable of absorbing the microorganism marker gas and thereafter releasing a concentrated microorganism marker gas; and an array of sensors in fluid communication with the concentrated microorganism marker gas. The sensor array detects and identifies the marker gas upon its release from fluid concentrate.
    Type: Grant
    Filed: June 17, 1999
    Date of Patent: June 12, 2001
    Assignee: California Institute of Technology
    Inventors: Nathan S. Lewis, Erik J. Severin, Bernard Wong