Abstract: A node for a radio communication network with dynamic reservation of transmission capacity is provided. Said node comprises a communication unit for communicating with at least one neighboring node, and at least one antenna coupled to said communication unit. In this context, the communication unit is configured to reserve transmission capacity on the basis of at least one RTS and/or CTS and/or nCTS handshake packet. In addition to this, the communication unit is further configured to limit transmission capacity reservation to a certain number of the at least one neighboring node on the basis of certain properties with respect to said certain number of the at least one neighboring node.

Abstract: This invention relates to a synthetic method for the preparation of Compound 1 and precursors thereof. Compound 1 is prepared via reaction of isoxazole 2 with phenylether (R)-3-ONa.

Abstract: A system (1) for estimating the brain blood volume and/or brain blood flow and/or depth of anesthesia of a patient, comprises at least one excitation electrode (110E) to be placed on the head (20) of a patient (2) for applying an excitation signal, at least one sensing electrode (110S) to be placed on the head (20) of the patient (2) for sensing a measurement signal caused by the excitation signal, and a processor device (12) for processing said measurement signal (VC) sensed by the at least one sensing electrode (110S) for determining an output indicative of the brain blood volume and/or the brain blood flow. Herein, the processor device (12) is constituted to reduce noise in the measurement signal (VC) by applying a non-linear noise-reduction algorithm. In this way a system for estimating the brain blood volume and/or the brain blood flow of a patient is provided which may lead to an increased accuracy and hence more exact estimates.

Abstract: Method for training a model usable to compute an index of nociception A method for training a model (M2) usable to compute an index of nociception (qNOX) related to a nociception effect during a general anesthesia procedure comprises: obtaining, during a training phase separate from an actual use of the model (M2) during an anesthesia procedure, clinical data relating to a multiplicity of previous anesthesia procedures; deriving training data (TD) from said clinical data; deriving reference data (RD) from said clinical data; and training said model (M2) using said training data (TD) as input data to the model (M2) and said reference data (RD) as output data to the model (M2), wherein said training includes adjusting the model (M2) according to the training data (TD) and the reference data (RD).

Abstract: The present invention disclosed a device and method for assessing in real time the hypnotic and analgesic effect in a subject during wakefulness, sedation and general anaesthesia via drug interactions and physiological signals. In a preferred embodiment of the present invention, the analgesic and hypnotic effect of drug(s) infused in a subject could be accurately assessed in real time through the device and method disclosed in the present invention, comprising steps of receiving data from electroencephalography (EEG) device, receiving data from brain impedance tomography device, obtaining pharmacodynamic and pharmacokinetic parameters of drug(s) infused in the subject, defining initial indices of consciousness and nociception as a function of said EEG and brain impedance tomography data, and generating output of final indices of consciousness and nociception in real time from processing input of EEG, brain tomography and drug interaction data using established mathematical manipulation.

Abstract: A system for measuring a substance concentration in the exhaled breath of a patient (4) comprises a measurement apparatus (21) for performing an ion mobility spectrometry measurement of a gas probe of the exhaled breath of the patient to obtain a recorded data set (R) indicative of a drift spectrum (S) relating to the gas probe, and a processor (20) for processing the recorded data set (R) to determine at least one characteristic value relating to the drift spectrum (S) and to output a concentration estimate indicative N of the substance concentration in the gas probe. Herein, the processor (20) is constituted to fit an autoregressive model to at least a portion of the recorded data set (R) to obtain a fitted data set (F), wherein the processor (20) is further constituted to determine said at least one characteristic value from the fitted data set (F).

Abstract: A system (1) for estimating the stroke volume and/or the cardiac output of a patient, comprises a processor device (12) constituted to receive a bio-impedance measurement signal (VC) relating to a bio-impedance measurement on the thorax (2) of a patient (2), process the bio-impedance measurement signal (VC) to extract a group of characteristic features from the bio-impedance measurement signal (DVC) and/or its derivative (DVC), and determine, using the group of extracted characteristic features, an output value indicative of the stroke volume and/or the cardiac output using at least one non-linear model (110, 111). The processor device (12) furthermore is constituted to process the bio-impedance measurement signal (VC) to compute at least one time-frequency distribution (TFD) based on the bio-impedance measurement signal (VC) and/or its derivative and to determine at least one characteristic feature of said group of characteristic features based on the at least one time-frequency distribution (TFD).

Abstract: A system (1) for estimating the brain blood volume and/or brain blood flow and/or depth of anesthesia of a patient, comprises at least one excitation electrode (110E) to be placed on the head (20) of a patient (2) for applying an excitation signal, at least one sensing electrode (110S) to be placed on the head (20) of the patient (2) for sensing a measurement signal caused by the excitation signal, and a processor device (12) for processing said measurement signal (VC) sensed by the at least one sensing electrode (110S) for determining an output indicative of the brain blood volume and/or the brain blood flow. Herein, the processor device (12) is constituted to reduce noise in the measurement signal (VC) by applying a non-linear noise-reduction algorithm. In this way a system for estimating the brain blood volume and/or the brain blood flow of a patient is provided which may lead to an increased accuracy and hence more exact estimates.

Abstract: A charging cable assembly for transmitting electrical energy between a power supply station and an electrically drivable vehicle with a charging cable outer sheathing, in which at least one current conductor cable with a current conductor outer sheathing and at least one coolant line with a heat transfer surface are arranged, there being provided at least one heat transfer layer, which lies at least partially against the heat transfer surface and the current conductor outer sheathing.

Abstract: Apparatus for determining stroke volume, cardiac output and systemic inflammation by fuzzy logic combination of features extracted from a voltage measured over the thorax, electrocardiogram and electroencephalogram comprising a) sensor for measuring electroencephalogram; b) sensor for measuring the electrocardiogram; c) calculating the heart rate variability from the electrocardiogram; d) two electrodes (1, 2) for measuring the voltage generated by a constant current generator in two other electrodes (1, 2); e) calculating the area under the curve of voltage for each heart-beat; f) calculating the derivative of the voltage curve; g) calculating the transfer entropy between EEG and ECG; h) combining at least 3 extracted parameters using an Adaptive Neuro Fuzzy inference system (ANFIS) or any other fuzzy reasoner into a final index of cardiac output; i) combining at least 3 extracted parameters using an Adaptive Neuro Fuzzy Inference System or any other fuzzy reasoner into a final index of systemic inflammation

Abstract: The invention relates to a vehicle seat (1) comprising a seat element (2) which can be pivoted from a use position into a stowed position. Said vehicle seat comprises locking means (14). Said locking means interact with the seat element (2) in a positive and/or friction fit in a fixed position adopted in the use position, along a first direction (F) and a second direction (G).

Abstract: A charging cable assembly for transmitting electrical energy between a power supply station and an electrically drivable vehicle with a charging cable outer sheathing, in which at least one current conductor cable with a current conductor outer sheathing and at least one coolant line with a heat transfer surface are arranged, there being provided at least one heat transfer layer, which lies at least partially against the heat transfer surface and the current conductor outer sheathing.

Abstract: The present invention disclosed a device and method for assessing in real time the hypnotic and analgesic effect in a subject during wakefulness, sedation and general anaesthesia via drug interactions and physiological signals. In a preferred embodiment of the present invention, the analgesic and hypnotic effect of drug(s) infused in a subject could be accurately assessed in real time through the device and method disclosed in the present invention, comprising steps of receiving data from electroencephalography (EEG) device, receiving data from brain impedance tomography device, obtaining pharmacodynamic and pharmacokinetic parameters of drug(s) infused in the subject, defining initial indices of consciousness and nociception as a function of said EEG and brain impedance tomography data, and generating output of final indices of consciousness and nociception in real time from processing input of EEG, brain tomography and drug interaction data using established mathematical manipulation.

Abstract: Roadway barrier bicycle safety apparatus for attachment to an upper portion of a roadway barrier segment for topping the upper portion to prevent a bicycle from extending over the upper portion. The apparatus includes a shell having a curved upper surface and configured to prevent snagging of a bicycle or bicycle rider.

Abstract: Means and methods for measuring pain and adapted for calculating the level of nociception during general anesthesia or sedation from data including electroencephalogram (EEG), facial electromyogram (EMG), heart rate variability (HRV) by electrocardiogram (ECG) and plethysmography by impedance cardiography (ICG). In a preferred embodiment of this invention the parameters derived from the EEG, the HRV, the plethysmographic curve and the analgetics concentrations are either combined into one index on a scale from 0 to 100, where a high number is associated with high probability of response to noxious stimuli, while a decreasing index is associated with decreasing probability of response to noxious stimuli. Zero (0) indicates extremely low probability of response to noxious stimuli. In an alternative embodiment, only features from the EEG and ECG will be used or only features from EEG, ECG and ICG, to define the fmal index.

Abstract: Apparatus for determining stroke volume, cardiac output and systemic inflammation by fuzzy logic combination of features extracted from a voltage measured over the thorax, electrocardiogram and electroencephalogram comprising a) sensor for measuring electroencephalogram; b) sensor for measuring the electrocardiogram; c) calculating the heart rate variability from the electrocardiogram; d) two electrodes (1, 2) for measuring the voltage generated by a constant current generator in two other electrodes (1, 2); e) calculating the area under the curve of voltage for each heart-beat; f) calculating the derivative of the voltage curve; g) calculating the transfer entropy between EEG and ECG; h) combining at least 3 extracted parameters using an Adaptive Neuro Fuzzy inference system (ANFIS) or any other fuzzy reasoner into a final index of cardiac output; i) combining at least 3 extracted parameters using an Adaptive Neuro Fuzzy Inference System or any other fuzzy reasoner into a final index of systemic inflammation

Abstract: The invention relates to a vehicle seat (1) comprising a seat element (2) which can be pivoted from a use position into a stowed position. Said vehicle seat comprises locking means (14). Said locking means interact with the seat element (2) in a positive and/or friction fit in a fixed position adopted in the use position, along a first direction (F) and a second direction (G).

Abstract: A foot support (30) for a vehicle seat (1) includes a footrest (32) which is movable from an out-of-use position into a use position. The footrest (32) is guided by a linear guide during the movement from the out-of-use position into the use position. A drive unit (34) is provided for driving the footrest (32). The drive unit (34) includes at least one spindle (40) with at least one spindle nut (42, 44), which is arranged on the spindle (40) and is rotatable relative to the spindle (40). The spindle (40) runs in the transverse direction and includes two threaded regions (46, 48) with threads oriented in opposed directions. A vehicle seat (1) is provided with the foot support (30).