Patents by Inventor Eriko Shimamura

Eriko Shimamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kit for producing cleared biological specimens and method for producing cleared biological specimens
    Patent number: 11035763
    Abstract: A method and a kit are provided to produce a biological clear specimen within a short time and with a wide variety of biological specimens. The method includes the following steps: (1) treating a material to be cleared with an aqueous fixing solution containing paraformaldehyde or the like, a nonionic surfactant, an alkali, and optionally a buffering agent; (2) treating the material from step (1) or a conventionally fixed material with an aqueous clearing accelerator solution containing a nonionic surfactant and an alkali; and (3) treating the material produced in step (1) or (2) with an aqueous preservation solution containing a nonionic surfactant and a polyhydric alcohol. In each of the steps, the nonionic surfactant is present at a concentration of 1% or more. The kit includes solutions used in each of the steps of the method.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: June 15, 2021
    Assignee: KANAZAWA MEDICAL UNIVERSITY
    Inventors: Toshihisa Hatta, Maimi Uchishiba, Nobuaki Higashi, Hiroki Shimada, Eriko Shimamura
  • Method For Enucleating Nucleated Erythrocyte, And Enucleation Inducer
    Publication number: 20160222350
    Abstract: Provided is a factor capable of inducing enucleation, which is a final stage of erythrocyte differentiation, within a short time. More particularly, provided are a method of inducing enucleation, which is a final stage of erythrocyte differentiation, within a short time by adding a compound derived from proopiomelanocortin (POMC) to an undifferentiated (nucleated) erythrocyte, and an enucleation inducer including the compound.
    Type: Application
    Filed: February 3, 2016
    Publication date: August 4, 2016
    Applicant: Kanazawa Medical University
    Inventors: Toshihisa Hatta, Eriko Shimamura, Hiroki Shimada
  • Method for enucleating nucleated erythrocyte, and enucleation inducer
    Patent number: 9290737
    Abstract: Provided is a factor capable of inducing enucleation, which is a final stage of erythrocyte differentiation, within a short time. More particularly, provided are a method of inducing enucleation, which is a final stage of erythrocyte differentiation, within a short time by adding a compound derived from proopiomelanocortin (POMC) to an undifferentiated (nucleated) erythrocyte, and an enucleation inducer including the compound.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: March 22, 2016
    Assignee: Kanazawa Medical University
    Inventors: Toshihisa Hatta, Eriko Shimamura, Hiroki Shimada
  • KIT FOR PRODUCING CLEARED BIOLOGICAL SPECIMENS AND METHOD FOR PRODUCING CLEARED BIOLOGICAL SPECIMENS
    Publication number: 20150285718
    Abstract: A method and a kit are provided to produce a biological clear specimen within a short time and with a wide variety of biological specimens. The method includes the following steps: (1) treating a material to be cleared with an aqueous fixing solution containing paraformaldehyde or the like, a nonionic surfactant, an alkali, and optionally a buffering agent; (2) treating the material from step (1) or a conventionally fixed material with an aqueous clearing accelerator solution containing a nonionic surfactant and an alkali; and (3) treating the material produced in step (1) or (2) with an aqueous preservation solution containing a nonionic surfactant and a polyhydric alcohol. In each of the steps, the nonionic surfactant is present at a concentration of 1% or more. The kit includes solutions used in each of the steps of the method.
    Type: Application
    Filed: October 30, 2013
    Publication date: October 8, 2015
    Inventors: Toshihisa Hatta, Maimi Uchishiba, Nobuaki Higashi, Hiroki Shimada, Eriko Shimamura
  • Method For Enucleating Nucleated Erythrocyte, And Enucleation Inducer
    Publication number: 20120070897
    Abstract: Provided is a factor capable of inducing enucleation, which is a final stage of erythrocyte differentiation, within a short time. More particularly, provided are a method of inducing enucleation, which is a final stage of erythrocyte differentiation, within a short time by adding a compound derived from proopiomelanocortin (POMC) to an undifferentiated (nucleated) erythrocyte, and an enucleation inducer including the compound.
    Type: Application
    Filed: February 23, 2010
    Publication date: March 22, 2012
    Inventors: Toshihisa Hatta, Eriko Shimamura, Hiroki Shimada