Abstract: The invention relates to a pharmaceutical composition for removing necrotic skin tissue in mammals, including humans. The composition comprises in combination a substituted thiol in which the hydrogen sulfide moiety is substituted by an organic residue, alantoine, a physiologically acceptable alkaline substance, an application vehicle for the thiol and alkaline constituents, and water for activating the composition. Suitable application vehicles are body giving materials of an oily nature, emulsifiers and a thickening agent, with adequate water to provide the required consistency. Suitable thiols are thioglycolates and similar compounds.

Abstract: A pharmaceutical preparation, for oral ingestion after dissolution in a suitable palatable liquid, comprising in combination acetylsalicylic acid, a solubilizing agent adapted to result in a substantially complete dissolution of the acetylsalicylic acid and dry milk solids in a quantity of from 10 to 100 times the weight of the active ingredient. The preferred solubilizing agent is a combination of physiologically acceptable alkali metal carbonate and bicarbonate. The preparations are preferably provided in unit dosage form in the form of a fine powdery mixture sealed in a moisture-proof package.