Abstract: A diagnostic test strip for chemically determining whole blood analytes comprises a support, a porous detection zone membrane affixed to the support, and an overlay membrane affixed to the support and in overlying and continuous contact with the detection zone membrane. The overlay membrane has a crenating agent for the exclusion of whole red blood cells from the pores of the detection zone membrane.

Abstract: Single or multiple blood plasma component concentrations are measured by a disposable stick having one or more blood plasma component reactive areas covered by a semipermeable membrane which is permeable by blood plasma or serum components and impermeable by blood cellular and particulate matter. A second overlay may be superposed with the semipermeable membrane over the reactive areas to receive a blood sample and meter and distribute that sample uniformly to the semipermeable membrane which in turn passes the plasma components uniformly to the reactive areas. The overlays are subsequently separable from the reactive area to remove the cellular components and particulate matter and expose the reactive areas for inspection by, for example, color comparison to standardized charts.

Abstract: Single or multiple blood plasma component concentrations are measured by a disposable stick having one or more blood plasma component reactive areas covered by a semipermeable membrane which is permeable by blood plasma or serum components and inpermeable by blood cellular and particulate matter. A second overlap may be superposed with the semipermeable membrane over the reactive areas to receive a blood sample and meter and distribute that sample uniformly to the semipermeable membrane which in turn passes the plasma components uniformly to the reactive areas. The overlays are subsequently separable from the reactive area to remove the cellular components and particulate matter and expose the reactive areas for inspection by, for example, color comparison to standardized charts.

Abstract: Ethyl alcohol test strip fabricating and use techniques for testing an individual's saliva to determine his sobriety are disclosed. The test strips employ an alcohol oxidase, Peroxidase and an hydrogen donor indicator such as Tetraalkylbenzidine in a carrier matrix supported on the strip with the alcohol oxidase functioning as a catalyst to convert any ethanol present along with ambient oxygen to acetaldehyde and hydrogen peroxide. The peroxidase function as catalyst to induce a color change in the hydrogen donor and convert the hydrogen peroxide to water. The method of fabricating the test strip involves multiple steps of reagent application and hot air drying.

Abstract: A method for determining the amount of IgG present in a neonatal foal or calf or in the colostrum of a dam or cow. The method involves contacting a body fluid sample with biologically inert latex particles, measuring the amount of agglutination which occurs, and determining the amount of IgG present. The latex particles are diluted to a final concentration of from about 0.25 to 2.0 percent (w/v) at a pH of from about 7.5 to 9.0 with a buffer. The body fluid is diluted to a range of from 0.01:5 parts to 0.01:2160 parts, v/v basis, at a pH of from about 7.5 to 9.0.

Abstract: A test device and method for detecting myoglobin in the presence of hemoglobin in a fluid test sample. The test device comprises a chromatographic medium incorporating serum, haptoglobin and/or antiserum which binds or retards hemoglobin while permitting myoglobin to traverse the length of the test device. A test sample of body fluid is placed in contact with an appropriate portion of the chromatographic medium of said test device; hemoglobin in the body fluid is retained or retarded by the serum, haptoglobin and/or antiserum; and myoglobin in the sample traverses the length of the medium and contacts reagent means at a predetermined location thereon, resulting in a detectable response thereat.