Patents by Inventor Ernest Han

Ernest Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of enhancing the delivery of nucleic acids using silica nanoparticles
    Patent number: 6319715
    Abstract: The present invention provides a method for enhancing the delivery of nucleic acid molecules to cells by increasing the concentration of cells at the cell surface. The method comprises the step of premixing of nucleic acid:vector molecules with nanoparticles that are biocompatible, reversibly associate with the nucleic acids and have a sedimentation rate which increases the concentration of the nucleic acids at the cell surface so as to enhance delivery into the cells.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: November 20, 2001
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Dan Luo, W. Mark Saltzman, Ernest Han, Nadya Belcheva