Patents by Inventor Ernesto Landonio

Ernesto Landonio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal form of glycopyrronium chloride
    Patent number: 9174937
    Abstract: A new crystal form of threo glycopyrronium chloride is useful in pharmaceutical applications.
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: November 3, 2015
    Assignee: CHIESI FARMACEUTICI S.p.A.
    Inventors: Fausto Pivetti, Monica Bocchi, Enrico Vigano, Ernesto Landonio
  • CRYSTAL FORM OF GLYCOPYRRONIUM CHLORIDE
    Publication number: 20110305645
    Abstract: A new crystal form of threo glycopyrronium chloride is useful in pharmaceutical applications.
    Type: Application
    Filed: June 14, 2011
    Publication date: December 15, 2011
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Fausto Pivetti, Monica Bocchi, Enrico Vigano, Ernesto Landonio
  • Process for the resolution of racemic verapamil
    Patent number: 7803962
    Abstract: A new process is described for the resolution of racemic verapamil, which allows the desired enantiomer to be obtained in high yields and with high enantiomeric purity. The process uses optically active 2,3-bis[(2-fluorobenzoyl)oxy]butanedioic acid as the resolving agent, and a water/dimethylformamide or water/acetonitrile or water/methanol mixture, as the reaction solvent.
    Type: Grant
    Filed: June 3, 2008
    Date of Patent: September 28, 2010
    Assignee: Cosma S.p.A.
    Inventors: Chiara Bertolotti, Massimiliano Lussana, Enrica Pizzatti, Enrico Vigano', Ernesto Landonio
  • Process for the purification of meloxicam
    Patent number: 7671197
    Abstract: The present invention relates to a process for the purification of meloxicam and in particular of the impurity composed of 4-hydroxy-2-methyl-N-ethyl-N?-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide and to meloxicam containing a quantity of less than 0.05% of the above-mentioned impurity (“ethylamide”).
    Type: Grant
    Filed: October 11, 2005
    Date of Patent: March 2, 2010
    Assignee: A.M.S.A. Anonima Materie Sintetiche E Affini S.p.A.
    Inventors: Enrico Vigano', Ernesto Landonio
  • Process for the resolution of racemic verapamil
    Publication number: 20080306296
    Abstract: A new process is described for the resolution of racemic verapamil, which allows the desired enantiomer to be obtained in high yields and with high enantiomeric purity. The process uses optically active 2,3-bis[(2-fluorobenzoyl)oxy]butanedioic acid as the resolving agent, and a water/dimethylformamide or water/acetonitrile or water/methanol mixture, as the reaction solvent.
    Type: Application
    Filed: June 3, 2008
    Publication date: December 11, 2008
    Inventors: Chiara Bertolotti, Massimiliano Lussana, Enrica Pizzatti, Enrico Vigano, Ernesto Landonio
  • Process for the preparation of nateglinide, preferably in B-form
    Patent number: 7425648
    Abstract: The present invention relates to a process for the preparation of nateglinide, preferably in B-form, substantially free from the H-form, comprising three steps starting from D-phenylalanine methyl ester or a salt thereof.
    Type: Grant
    Filed: January 3, 2005
    Date of Patent: September 16, 2008
    Assignee: A.M.S.A. Anonima Materie Sintetiche E. Affini S.p.A.
    Inventors: Enrico Vigano', Enrica Pizzatti, Simona Lanfranconi, Renato Molteni, Ernesto Landonio
  • Process for synthesising aminoadamantanes
    Patent number: 7405324
    Abstract: The present invention concerns a new process for synthesising aminoadamantanes of formula I in which R1 and R2 are identical or different and are H or a straight or branched alkyl group comprising from 1 to 6 carbon atoms, and addition salts thereof with inorganic or organic acids, in particular memantine hydrochloride (1-amino-3,5-dimethyladamantane hydrochloride).
    Type: Grant
    Filed: May 10, 2006
    Date of Patent: July 29, 2008
    Assignee: A.M.S.A. Anonima Materie Sintetiche E. Afini S.p.A.
    Inventors: Enrico Vigano′, Ernesto Landonio, Simona Lanfranconi, Renato Molteni
  • Process for synthesising aminoadamantanes
    Publication number: 20060258885
    Abstract: The present invention concerns a new process for synthesising aminoadamantanes of formula I in which R1 and R2 are identical or different and are H or a straight or branched alkyl group comprising from 1 to 6 carbon atoms, and addition salts thereof with inorganic or organic acids, in particular memantine hydrochloride (1-amino-3,5-dimethyladamantane hydrochloride).
    Type: Application
    Filed: May 10, 2006
    Publication date: November 16, 2006
    Inventors: Enrico Vigano, Ernesto Landonio, Simona Lanfranconi, Renato Molteni
  • Process for the preparation of nateglinide, preferably in B-form
    Publication number: 20060148902
    Abstract: The present invention relates to a process for the preparation of nateglinide, preferably in B-form, substantially free from the H-form, comprising three steps starting from D-phenylalanine methyl ester or a salt thereof.
    Type: Application
    Filed: January 3, 2005
    Publication date: July 6, 2006
    Inventors: Enrico Vigano', Enrica Pizzatti, Simona Lanfranconi, Renato Molteni, Ernesto Landonio
  • Process for the purification of meloxicam
    Publication number: 20060116514
    Abstract: The present invention relates to a process for the purification of meloxicam and in particular of the impurity composed of 4-hydroxy-2-methyl-N-ethyl-N?-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide and to meloxicam containing a quantity of less than 0.05% of the above-mentioned impurity (“ethylamide”).
    Type: Application
    Filed: October 11, 2005
    Publication date: June 1, 2006
    Inventors: Enrico Vigano, Ernesto Landonio
  • Procedure for the synthesis of bicalutamide
    Publication number: 20060041161
    Abstract: The object of the invention is an improved procedure for the synthesis of bicalutamide, characterised in that the 2-hydroxy-2-methyl-3-(4-fluorophenylthio) propionic acid initially produced undergoes a step to acylate the hydroxyl group in position 2 to give an intermediate 2-acyloxy-2-methyl-3-(4-fluorophenylthio) propionic acid, which allows the formation of a successive N-[4-cyano-3-(trifluoromethyl)-phenyl-]-3-[4-fluorophenylthio]-2-acyloxy-2-methyl-propionamide intermediate.
    Type: Application
    Filed: May 24, 2005
    Publication date: February 23, 2006
    Inventors: Enrica Pizzatti, Enrico Vigano, Massimiliano Lussana, Ernesto Landonio