Patents by Inventor Erzsebet Szilagyi

Erzsebet Szilagyi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Activated mesenchymal stem cells for wound healing and impaired tissue regeneration
    Patent number: 9011840
    Abstract: Inflammatory cytokines e.g. IFN-?, serve as initiating stimuli for mesenchymal stem cell (MSC) immunosuppresive activity in vivo. Other inflammatory cytokines, such as TNF alpha, the molecule hemoxygenase I, and TLR ligation of MSC, may also provide such a response. Activated MSC's promote tissue regeneration in conditions such as aging, where regeneration is impaired. Wound healing in aged mammals was enhanced by restoring tensile strength to the levels of younger mammals. Activated MSCs were useful in treating wounds in diabetic primates.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: April 21, 2015
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Amelia Bartholomew, Simon Lee, Erzsebet Szilagyi
  • ACTIVATED MESENCHYMAL STEM CELLS FOR WOUND HEALING AND IMPAIRED TISSUE REGENERATION
    Publication number: 20130017175
    Abstract: Inflammatory cytokines e.g. IFN-?, serve as initiating stimuli for mesenchymal stem cell (MSC) immunosuppresive activity in vivo. Other inflammatory cytokines, such as TNF alpha, the molecule hemoxygenase I, and TLR ligation of MSC, may also provide such a response. Activated MSC's promote tissue regeneration in conditions such as aging, where regeneration is impaired. Wound healing in aged mammals was enhanced by restoring tensile strength to the levels of younger mammals. Activated MSCs were useful in treating wounds in diabetic primates.
    Type: Application
    Filed: May 30, 2012
    Publication date: January 17, 2013
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Amelia Bartholomew, Simon Lee, Erzsebet Szilagyi
  • ACTIVATED MESENCHYMAL STEM CELLS FOR THE PREVENTION AND REPAIR OF INFLAMMATORY STATES
    Publication number: 20110044958
    Abstract: Inflammatory cytokines e.g. IFN-? serve as initiating stimuli for MSC immunosuppressive activity in vivo. Other inflammatory cytokines, such as TNF alpha, the molecule hemoxygenase I, and TLR ligation of MSC may also provide such a response.
    Type: Application
    Filed: March 16, 2009
    Publication date: February 24, 2011
    Inventors: Amelia Bartholomewq, David Polchert, Erzsebet Szilagyi