Patents by Inventor Eskild Petersen

Eskild Petersen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Positively charged co-polymers for use as antimicrobial agents
    Patent number: 10166253
    Abstract: The present invention provides a positively charged co-polymer for use as an antimicrobial agent, wherein said positively charged co-polymer is composed of amino acids and/or derivatives thereof and wherein at least 75 molar percent of said amino acids are selected from the group consisting of alanine, lysine, glutamate, arginine and tyrosine and/or derivatives thereof. The present invention also provides methods for treating, preventing or ameliorating a microbial infection comprising administration of positively charged random co-polymers as well as a pharmaceutical composition comprising said co-polymer. The invention further provides a kit of parts comprising the positively charged random co-polymer.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: January 1, 2019
    Assignees: Region Midtjylland, Aarhus Universitet
    Inventors: Thomas Vorup Jensen, Stig Hill Christiansen, Jørgen Eskild Petersen
  • Positively Charged Co-Polymers for Use as Antimicrobial Agents
    Publication number: 20170239288
    Abstract: The present invention provides a positively charged co-polymer for use as an antimicrobial agent,wherein said positively charged co-polymer is composed of amino acids and/or derivatives thereof and wherein at least 75 molar percent of said amino acids are selected from the group consisting of alanine, lysine, glutamate, arginine and tyrosine and/or derivatives thereof. The present invention also provides methods for treating, preventing or ameliorating a microbial infection comprising administration of positively charged random co-polymers as well as a pharmaceutical composition comprising said co-polymer. The invention further provides a kit of parts comprising the positively charged random co-polymer.
    Type: Application
    Filed: August 28, 2015
    Publication date: August 24, 2017
    Inventors: Thomas Vorup JENSEN, Stig Hill CHRISTIANSEN, Jørgen Eskild PETERSEN
  • Antibiotic formulation and use for bacterial infections
    Patent number: 6221388
    Abstract: A liposomal aminoglycoside formulation comprising a neutral lipid, a negatively charged lipids and a sterol. The formulation contains unilamellar vesicles having an average size below 100 nm. A process of making liposomes containing an aminoglycoside is also provided. A method is also provided for the treatment of drug susceptible and drug resistant bacteria.
    Type: Grant
    Filed: September 28, 1999
    Date of Patent: April 24, 2001
    Assignee: Gilead Sciences, Inc.
    Inventors: Evan M. Hersch, Eskild A. Petersen, Richard T. Proffitt, Kevin R. Bracken, Su-Ming Chiang
  • Antibiotic formulation and use for bacterial infections
    Patent number: 5958449
    Abstract: A liposomal aminoglycoside formulation comprising a neutral lipid, a negatively charged lipid and a sterol. The formulation contains unilamellar vesicles having an average size below 100 nm. A process of making liposomes containing an aminoglycoside is provided. A method is also provide for the treatment of drug susceptible and drug resistant bacteria.
    Type: Grant
    Filed: May 21, 1998
    Date of Patent: September 28, 1999
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Evan M. Hersch, Eskild A. Petersen, Richard T. Proffitt, Kevin R. Bracken, Su-Ming Chiang
  • Monoclonal antibodies specific for HIV and the hybridomas for production thereof
    Patent number: 5783670
    Abstract: Human monoclonal antibodies which belong to the IgGl subclass and are specific for HIV are described. The monoclonal antibodies have potential for use in the diagnosis, prevention and therapy of HIV infection.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 21, 1998
    Assignees: The University of Arizona, Department of Internal Medicine, Section of Hematology and Oncology, Teijin Limited
    Inventors: Yasuhiko Masuho, Toru Sugano, Yoh-ichi Matsumoto, Takashi Kawamura, Evan Hersh, Eskild Petersen, Douglas Lake
  • Antibiotic formulation and use for drug resistant infections
    Patent number: 5759571
    Abstract: A liposomal aminoglycoside formulation comprising a neutral lipid, a negatively charged lipids and a sterol. The formulation contains unilamellar vesicles having an average size below 100 nm. A process of making liposomes containing an aminoglycoside is provided where the hydration temperature is significantly below the transition temperature of the formulation. A method for the treatment of drug susceptible and drug resistant bacteria.
    Type: Grant
    Filed: June 23, 1993
    Date of Patent: June 2, 1998
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Evan M. Hersch, Eskild A. Petersen, Richard T. Proffitt, Kevin R. Bracken, Su-Ming Chiang
  • Antibiotic formulation and use for drug resistant infections
    Patent number: 5756120
    Abstract: A liposomal aminoglycoside formulation comprising a neutral lipid, a negatively charged lipids and a sterol. The formulation contains unilamellar vesicles having an average size below 100 nm. A process of making liposomes containing an aminoglycoside is provided where the hydration temperature is significantly below the transition temperature of the formulation. A method for the treatment of drug susceptible and drug resistant bacteria.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 26, 1998
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Evan M. Hersch, Eskild A. Petersen, Richard T. Proffitt, Kevin R. Bracken, Su-Ming Chiang
  • Monoclonal antibodies specific for HIV and the hybridomas for production thereof
    Patent number: 5695927
    Abstract: Human monoclonal antibodies which belong to the IgG1 subclass and are specific for HIV are described. The monoclonal antibodies have potential for use in the diagnosis, prevention and therapy of HIV infection.
    Type: Grant
    Filed: July 1, 1994
    Date of Patent: December 9, 1997
    Assignees: The University of Arizona, Department of Internal Medicine, Section of Hematology and Oncology, Teijin Limited
    Inventors: Yasuhiko Masuho, Toru Sugano, Yoh-ichi Matsumoto, Takashi Kawamura, Evan Hersh, Eskild Petersen, Douglas Lake
  • Monoclonal antibodies specific for HIV and hybridomas for their production
    Patent number: 5445960
    Abstract: Human IgG1 monoclonal antibodies are produced by hybridoma ATCC HB10074 and bind to gp120 of HIV.
    Type: Grant
    Filed: May 24, 1993
    Date of Patent: August 29, 1995
    Assignees: The Arizona Board of Regents on behalf of the University of Arizona, Teijin Limited
    Inventors: Yasuhiko Masuho, Toru Sugano, Yoh-Ichi Matsumoto, Evan M. Hersh, Eskild A. Petersen, Douglas Lake, Takashi Kawamura