Patents by Inventor Esohe Idusogie

Esohe Idusogie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptide variants
    Publication number: 20060194954
    Abstract: A variant of a polypeptide comprising a human IgG Fc region is described, which variant comprises an amino acid substitution at one or more of amino acid positions 270, 322, 326, 327, 329, 331, 333 or 334 of the human IgG Fc region. Such variants display altered effector function. For example, C1q binding and/or complement dependent cytotoxicity (CDC) activity may be altered in the variant polypeptide.
    Type: Application
    Filed: May 5, 2006
    Publication date: August 31, 2006
    Inventors: Esohe Idusogie, Leonard Presta, Michael Mulkerrin