Patents by Inventor Esteban Roman Vela

Esteban Roman Vela has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-carboaryl-oxy-pyrazin-2-yl-carboaryl-amines and compositions comprising said compounds
    Patent number: 7737152
    Abstract: The present invention pertains to certain 6-carboaryloxy-pyrazin-2-yl-carboaryl-amines of the following formula, and pharmaceutically acceptable salts thereof, which, inter alia, inhibit RAF (e.g., B-RAF) activity, inhibit cell proliferation, treat cancer, etc., wherein Q is independently —N?; RP3 is independently a group of the formula -J1-L1-Z; -J1L1-Z is independently —NH—Z; Z is independently C6-14carboaryl and is independently unsubstituted or substituted; RP2 is independently —H; RP5 is independently a group of the formula —W—Y; W is independently —O—; Y is independently C6-14 carboaryl and is independently unsubstituted or substituted; and RP6 is independently —H. The present invention also pertains to pharmaceutical compositions comprising such compounds.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: June 15, 2010
    Assignee: The Wellcome Trust Limited
    Inventors: Caroline Joy Springer, Ion Niculescu-Duvaz, Esteban Roman Vela, Adrian Liam Gill, Richard David Taylor, Richard Malcolm Marais
  • Imidazo[4,5-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-one compounds and analogs thereof as therapeutic compounds
    Patent number: 7625922
    Abstract: The present invention pertains to certain imidazo[4,5-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-one compounds and analogs thereof, which, inter alia, inhibit RAF (e.g., B-RAF) activity, inhibit cell proliferation, treat cancer, etc.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: December 1, 2009
    Assignees: Cancer Research Technology Limited, The Institute of Cancer Research: Royal Cancer Hospital, Astex Therapeutics Limited
    Inventors: Dan Niculescu-Duvaz, Caroline Joy Springer, Adrian Liam Gill, Richard David Taylor, Richard Malcol Marais, Harmen Dijkstra, Catherine Gaulon, Delphine Menard, Esteban Roman Vela
  • Imidazo[4,5-B]Pyridin-2-One and Oxazolo[4,5-B]Pyridin-2-One Compounds and Analogs Thereof as Therapeutic Compounds
    Publication number: 20070287838
    Abstract: The present invention pertains to certain imidazo[4,5-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-one compounds and analogs thereof, which, inter alia, inhibit RAF (e.g., B-RAF) activity, inhibit cell proliferation, treat cancer, etc.
    Type: Application
    Filed: October 21, 2005
    Publication date: December 13, 2007
    Applicants: CANCER RESEARCH TECHNOLOGY LIMITED, INSTITUE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE), ASTEX THERAPEUTICS LIMITED
    Inventors: Dan Niculescu-Duvaz, Caroline Springer, Adrian Gill, Richard Taylor, Richard Marais, Hermen Dijkstra, Catherine Gaulon, Delphine Menard, Esteban Roman Vela