Patents by Inventor Ester J. Kwon

Ester J. Kwon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS TO SPATIALLY PROFILE PROTEASE ACTIVITY IN TISSUE AND SECTIONS
    Publication number: 20230076516
    Abstract: Aspects of the disclosure relate to methods and compositions useful for in vivo and/or in vitro enzyme profiling. In some embodiments, the disclosure provides methods of in vivo enzymatic processing of exogenous molecules followed by detection of signature molecules as representative of the presence of active enzymes associated with diseases or conditions. In some embodiments, the disclosure provides compositions and in vitro methods for localization of enzymatic activity in a tissue sample.
    Type: Application
    Filed: October 26, 2022
    Publication date: March 9, 2023
    Applicant: Massachusetts Institute of Technology
    Inventors: Sangeeta N. Bhatia, Jaideep S. Dudani, Ester J. Kwon, Andrew David Warren
  • Methods to spatially profile protease activity in tissue and sections
    Patent number: 11519905
    Abstract: Aspects of the disclosure relate to methods and compositions useful for in vivo and/or in vitro enzyme profiling. In some embodiments, the disclosure provides methods of in vivo enzymatic processing of exogenous molecules followed by detection of signature molecules as representative of the presence of active enzymes associated with diseases or conditions. In some embodiments, the disclosure provides compositions and in vitro methods for localization of enzymatic activity in a tissue sample.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: December 6, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Sangeeta N. Bhatia, Jaideep S. Dudani, Ester J. Kwon, Andrew David Warren
  • METHODS TO SPATIALLY PROFILE PROTEASE ACTIVITY IN TISSUE AND SECTIONS
    Publication number: 20180335429
    Abstract: Aspects of the disclosure relate to methods and compositions useful for in vivo and/or in vitro enzyme profiling. In some embodiments, the disclosure provides methods of in vivo enzymatic processing of exogenous molecules followed by detection of signature molecules as representative of the presence of active enzymes associated with diseases or conditions. In some embodiments, the disclosure provides compositions and in vitro methods for localization of enzymatic activity in a tissue sample.
    Type: Application
    Filed: April 6, 2018
    Publication date: November 22, 2018
    Applicant: Massachusetts Institute of Technology
    Inventors: Sangeeta N. Bhatia, Jaideep S. Dudani, Ester J. Kwon, Andrew David Warren