Patents by Inventor Esther H. Oh

Esther H. Oh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF DIAGNOSING TISSUE FIBROSIS
    Publication number: 20100317022
    Abstract: The present invention provides a method of diagnosing the presence or severity of tissue fibrosis in an individual by detecting ?2-macroglobulin (?2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of tissue fibrosis in the individual based on the presence or level of ?2-MG, HA and TIMP-1.
    Type: Application
    Filed: January 27, 2010
    Publication date: December 16, 2010
    Applicant: Prometheus Laboratories Inc.
    Inventors: Esther H. Oh, Catherine M. Smith
  • Methods of diagnosing inflammatory bowel disease
    Patent number: 7759079
    Abstract: The present invention provides methods for diagnosing the presence or severity of inflammatory bowel disease (IBD) in an individual and methods for stratifying IBD by determining the level of one or more IBD markers in a sample from the individual and calculating an index value using an algorithm based upon the level of the IBD markers. Methods for monitoring the efficacy of IBD therapy, monitoring the progression or regression of IBD, and optimizing therapy in an individual having IBD are also provided.
    Type: Grant
    Filed: May 11, 2005
    Date of Patent: July 20, 2010
    Assignee: Prometheus Laboratories Inc.
    Inventors: Esther H. Oh, John F. Marcelletti, Susan M. Carroll, Katie M. Smith
  • Methods of diagnosing tissue fibrosis
    Patent number: 7670764
    Abstract: The present invention provides a method of diagnosing the presence or severity of tissue fibrosis in an individual by detecting ?2-macroglobulin (?2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of tissue fibrosis in the individual based on the presence or level of ?2-MG, HA and TIMP-1.
    Type: Grant
    Filed: October 22, 2004
    Date of Patent: March 2, 2010
    Assignee: Prometheus Laboratories Inc.
    Inventors: Esther H. Oh, Catherine M. Smith
  • Methods of diagnosing liver fibrosis
    Patent number: 6986995
    Abstract: The present invention provides a method of diagnosing the presence or severity of liver fibrosis in an individual by detecting ?2-macroglobulin (?2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of liver fibrosis in the individual based on the presence or level of ?2-MG, HA and TIMP-1.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: January 17, 2006
    Assignee: Prometheus Laboratories, Inc.
    Inventors: Steven L. Rose, Esther H. Oh, Michael J. Walsh
  • Methods of diagnosing liver fibrosis
    Publication number: 20030175686
    Abstract: The present invention provides a method of diagnosing the presence or severity of liver fibrosis in an individual by detecting &agr;2-macroglobulin (&agr;2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of liver fibrosis in the individual based on the presence or level of &agr;2-MG, HA and TIMP-1.
    Type: Application
    Filed: February 28, 2002
    Publication date: September 18, 2003
    Inventors: Steven L. Rose, Esther H. Oh, Michael J. Walsh