Patents by Inventor Ethel Macrea

Ethel Macrea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7550298
    Abstract: Provided herein are reagents for use in an automated environment for cell conditioning of biological samples wherein the cells or tissues are predisposed for access by reagent molecules for histochemical and cytochemical staining procedures. The reagents include, but are not limited to, components optimized to facilitate molecular access to cells and cell constituents within the biological sample. Also provided herein are reagents for use in an automated environment for removing or etching embedding media by exposing a biological sample to be stained in histochemical or cytochemical procedures without the dependence on organic solvents. The reagents include, but are not limited to, components optimized to facilitate removal or etching of the embedding media from the biological sample.
    Type: Grant
    Filed: March 7, 2002
    Date of Patent: June 23, 2009
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Penny Towne, Joseph Utermohlen, Chad Wilkinson, Paula Rodgers, Kimberly Christensen, Ethel Macrea, Noemi Sebastiao
  • Patent number: 7410753
    Abstract: The present invention provides reagents for use in an automated environment for removing or etching embedding media by exposing a biological sample to be stained in histochemical or cytochemical procedures without the dependence on organic solvents. The reagents comprise components optimized to facilitate removal or etching of the embedding media from the biological sample. The present invention also provides reagents for use in an automated environment for cell conditioning biological samples wherein the cells are predisposed for access by reagent molecules for histochemical and cytochemical staining procedures. The reagents comprise components optimized to facilitate molecular access to cells and cell constituents within the biological sample.
    Type: Grant
    Filed: March 21, 2003
    Date of Patent: August 12, 2008
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Keri Hopkins, Alexis Pusch, Catherine Wolf, Anthony Hartman, James Pettay, Kimberly Christensen, Ethel Macrea, Noemi Sebastiao
  • Patent number: 7067325
    Abstract: The present invention provides reagents for use in an automated environment for removing or etching embedding media by exposing a biological sample to be stained in histochemical or cytochemical procedures without the dependence on organic solvents. The reagents comprise components optimized to facilitate removal or etching of the embedding media from the biological sample. The present invention also provides reagents for use in an automated environment for cell conditioning biological samples wherein the cells are predisposed for access by reagent molecules for histochemical and cytochemical staining procedures. The reagents comprise components optimized to facilitate molecular access to cells and cell constituents within the biological sample.
    Type: Grant
    Filed: December 16, 2002
    Date of Patent: June 27, 2006
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Kimberly Christensen, Ethel Macrea, Noemi Sebastiao
  • Publication number: 20050118725
    Abstract: The present invention provides reagents for use in an automated environment for cell conditioning of biological samples wherein the cells or tissues are predisposed for access by reagent molecules for histochemical and cytochemical staining procedures. The reagents comprise components optimized to faciliate molecular access to cells and cell constituents within the biological sample. The present invention also provides reagents for use in an automated environment for removing or etching embedding media by exposing a biological sample to be stained in histochemical or cytochemical procedures without the dependence on organic solvents. The reagents comprise components optimized to facilitate removal or etching of the embedding media from the biological sample.
    Type: Application
    Filed: March 7, 2002
    Publication date: June 2, 2005
    Inventors: Penny Towne, Joseph Utermohlen, Chad Wilkinson, Paula Rodgers, Kimberly Christensen, Ethel Macrea, Noemi Sebastiao
  • Patent number: 6855552
    Abstract: The present invention provides reagents for use in an automated environment for cell conditioning of biological samples wherein the cells or tissues are predisposed for access by reagent molecules for histochemical and cytochemical staining procedures. The components of the reagents are optimized to facilitate molecular access to cells and cell constituents within the biological sample. The present invention also provides reagents for use in an automated environment for removing or etching embedding media by exposing a biological sample to be stained in histochemical or cytochemical procedures without the dependence on organic solvents. The components of the reagents are optimized to facilitate removal or etching of the embedding media from the biological sample.
    Type: Grant
    Filed: March 7, 2001
    Date of Patent: February 15, 2005
    Assignee: Ventana Medical Systems
    Inventors: Penny Towne, Joseph Utermohlen, Chad Wilkinson, Paula Rodgers, Kimberly Christensen, Ethel Macrea, Noemi Sebastiao
  • Publication number: 20040121485
    Abstract: The present invention provides reagents for use in an automated environment for removing or etching embedding media by exposing a biological sample to be stained in histochemical or cytochemical procedures without the dependence on organic solvents. The reagents comprise components optimized to facilitate removal or etching of the embedding media from the biological sample. The present invention also provides reagents for use in an automated environment for cell conditioning biological samples wherein the cells are predisposed for access by reagent molecules for histochemical and cytochemical staining procedures. The reagents comprise components optimized to facilitate molecular access to cells and cell constituents within the biological sample.
    Type: Application
    Filed: March 21, 2003
    Publication date: June 24, 2004
    Inventors: Keri Hopkins, Alexis Pusch, Catherine Wolf, Anthony Hartman, James Pettay, Kimberly Christensen, Ethel Macrea, Noemi Sebastiao
  • Publication number: 20030124729
    Abstract: The present invention provides reagents for use in an automated environment for removing or etching embedding media by exposing a biological sample to be stained in histochemical or cytochemical procedures without the dependence on organic solvents. The reagents comprise components optimized to facilitate removal or etching of the embedding media from the biological sample. The present invention also provides reagents for use in an automated environment for cell conditioning biological samples wherein the cells are predisposed for access by reagent molecules for histochemical and cytochemical staining procedures. The reagents comprise components optimized to facilitate molecular access to cells and cell constituents within the biological sample.
    Type: Application
    Filed: December 16, 2002
    Publication date: July 3, 2003
    Applicant: Ventana Medical Systems, Inc.
    Inventors: Kimberly Christensen, Ethel Macrea, Noemi Sebastiao