Patents by Inventor Ettore Lazzari

Ettore Lazzari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 3-substituted derivatives of 1-amino-2-hydroxy-propane
    Patent number: 5391735
    Abstract: The present invention relates to a new process for the preparation of 3-substituted derivatives of 1-amino-2-hydroxy-propane in the form of single diastereoisomers, to certain of these diastereoisomers, and to compounds which are intermediates in the new process of the invention.
    Type: Grant
    Filed: April 12, 1994
    Date of Patent: February 21, 1995
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Piero Melloni, Arturo D. Torre, Ettore Lazzari, Giuseppe Mazzini
  • Site specific alkylating agents
    Patent number: 5310752
    Abstract: The invention relates to distamycin A analogs of the following formula ##STR1## wherein n is 2, 3 or 4; A is an optionally substituted divalent radical chosen from ##STR2## and --Het-- wherein Het is a pentatomic or hexatomic heteromonocyclic ring, except pyrrole; and wherein either one of R.sub.1 and R.sub.2 is hydrogen and the other is an acylating moiety or R.sub.1 and R.sub.2 are both hydrogen or both alkyl groups optionally substituted, including the pharmaceutically acceptable salts of the said compounds.The compounds of the invention can be useful antitumor and antiviral agents.
    Type: Grant
    Filed: August 10, 1992
    Date of Patent: May 10, 1994
    Assignee: Farmitalia Carlo Erba SpA
    Inventors: Ettore Lazzari, Federico Arcamone, Sergio Penco, Maria A. Verini, Nicola Mongelli
  • Process for preparation of 3-substituted derivatives of 1-amino-2-hydroxy propane
    Patent number: 5068433
    Abstract: The present invention relates to a new process for the preparation of 3-substituted derivatives of 1-amino-2- hydroxy-propane in the form of single diastereoisomers, to certain of these diastereoisomers, and to compounds which are intermediates in the new process of the invention.
    Type: Grant
    Filed: June 11, 1990
    Date of Patent: November 26, 1991
    Assignee: Farmitalia Carlo Erba, S.r.l.
    Inventors: Piero Melloni, Arturo D. Torre, Ettore Lazzari, Giuseppe Mazzini
  • Site specific alkylating agents
    Patent number: 5049579
    Abstract: The invention relates to distamycin A analogs of the following formula ##STR1## wherein n is 2, 3 or 4; A is an optionally substituted divalent radical chosen from ##STR2## and -Het- wherein Het is a pentatomic or hexatomic heteromonocyclic ring, except pyrrole; and wherein either one of R.sub.1 and R.sub.2 is hydrogen and the other is an acylating moiety or R.sub.1 and R.sub.2 are both hydrogen or both alkyl groups optionally substituted, including the pharmaceutically acceptable salts of the said compounds.The compounds of the invention can be useful antitumor and antiviral agents.
    Type: Grant
    Filed: October 31, 1990
    Date of Patent: September 17, 1991
    Assignee: Farmitalia Carlo Erba, S.r.l.
    Inventors: Ettore Lazzari, Federico Arcamone, Sergio Penco, Maria A. Verini, Nicola Mongelli
  • Site specific alkylating agents
    Patent number: 5017599
    Abstract: The invention relates to distamycin A analogs of the following formula ##STR1## wherein n is 2, 3 or 4; A is an optionally substituted divalent radical chosen from ##STR2## and -Het- wherein Het is a pentatomic or hexatomic heteromonocyclic ring, except pyrrole; and wherein either one of R.sub.1 and R.sub.2 is hydrogen and the other is an acylating moiety or R.sub.1 and R.sub.2 are both hydrogen or both alkyl groups optionally substituted, including the pharmaceutically acceptable salts of the said compounds.The compounds of the invention can be useful antitumor and antiviral agents.
    Type: Grant
    Filed: February 21, 1990
    Date of Patent: May 21, 1991
    Assignee: Farmitalia Carlo Erba, SpA
    Inventors: Ettore Lazzari, Federico Arcamone, Sergio Penco, Maria A. Verini, Nicola Mongelli
  • Antipsycotic benzoxazines
    Patent number: 4558049
    Abstract: There are provided compounds of formula 1: ##STR1## wherein R=halogen atom or CN, NH.sub.2 and NO.sub.2 group, and pharmaceutically acceptable salts thereof.The compounds are antipsycotic agents.
    Type: Grant
    Filed: May 11, 1983
    Date of Patent: December 10, 1985
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Luigi Bernardi, Ettore Lazzari, Maria L. Malnati, Giuseppe Mazzini, Lorenzo Pegrassi, Alessandro Rossi
  • Daunosamine nucleosides
    Patent number: 4067968
    Abstract: The antitumor efficacy of the known antibiotics daunomycin (daunorubicin) and adriamycin (doxorubicin) is synergized by the use of said antibiotics together with a daunosamine nucleoside. The latter compounds are prepared by condensing a reactive protected daunosamine with a reactive protected heterocyclic base.
    Type: Grant
    Filed: December 2, 1976
    Date of Patent: January 10, 1978
    Assignee: Societa Farmaceutici Italia S.p.A.
    Inventors: Ettore Lazzari, Federico Arcamone, Aurelio DI Marco