Patents by Inventor Eugen Ermantraut
Eugen Ermantraut has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120321518Abstract: The present invention relates to devices and methods for performing assays, especially for determining the presence and/or amount of one or more analytes. In particular, the invention relates to a device for the detection of analytes, comprising a reversibly compressible matrix located between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and wherein the distance between the first surface and the second surface is variable. The invention also relates to a corresponding method using such a device for the detection of one or more species of analytes.Type: ApplicationFiled: August 28, 2012Publication date: December 20, 2012Applicant: CLONDIAG GMBHInventors: Eugen ERMANTRAUT, Torsten Schulz, Thomas Ellinger, Daniel Weicherding
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Patent number: 8278113Abstract: The present invention relates to devices and methods for performing assays, especially for determining the presence and/or amount of one or more analytes. In particular, the invention relates to a device for the detection of analytes, comprising a reversibly compressible matrix located between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and wherein the distance between the first surface and the second surface is variable. The invention also relates to a corresponding method using such a device for the detection of one or more species of analytes.Type: GrantFiled: July 14, 2009Date of Patent: October 2, 2012Assignee: Clondiag GmbHInventors: Eugen Ermantraut, Torsten Schulz, Thomas Ellinger, Daniel Weicherding
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Publication number: 20120088252Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.Type: ApplicationFiled: October 14, 2011Publication date: April 12, 2012Applicant: ALERE TECHNOLOGIES GmbHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Publication number: 20120058464Abstract: A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte.Type: ApplicationFiled: March 16, 2010Publication date: March 8, 2012Inventors: Eugen Ermantraut, Thomas Kaiser, Jens Tuchscheerer, Vico Baier, Torsten Schulz, Anke Wostemeyer
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Patent number: 8040494Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or the second surface.Type: GrantFiled: November 6, 2006Date of Patent: October 18, 2011Assignee: Clondiag GmbHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Publication number: 20110124114Abstract: A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte.Type: ApplicationFiled: March 16, 2009Publication date: May 26, 2011Inventors: Eugen Ermantraut, Thomas Kaiser, Jens Tuchscheerer, Vico Beier, Torsten Schulz, Anke Wöstemeyer
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Publication number: 20110071038Abstract: The present invention relates to devices and methods for performing assays, especially for determining the presence and/or amount of one or more analytes. In particular, the invention relates to a device for the detection of analytes, comprising a reversibly compressible matrix located between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and wherein the distance between the first surface and the second surface is variable. The invention also relates to a corresponding method using such a device for the detection of one or more species of analytes.Type: ApplicationFiled: July 14, 2009Publication date: March 24, 2011Applicant: CLONDIAG GMBHInventors: Eugen Ermantraut, Torsten Schulz, Thomas Ellinger, Daniel Weicherding
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Patent number: 7888074Abstract: The aim of the invention is to provide a device for duplicating and characterizing nucleic acids almost simultaneously and with a high sample throughput rate. The device consists of a chamber body with a recess whose edge sealingly holds an optically transparent chip. Said chip holds nucleic acids in individual spots on a detection surface. The chamber body is placed on an optically transparent chamber support with a bearing surface, in such a way that a capillary gap, which can be filled with a liquid sample, is formed between the detection surface of the chip facing towards the chamber support and said chamber support. The chamber body is provided with an inlet and an outlet, which are spatially separate from each other, and has a space, which laterally encompasses the chip and which has a gas reservoir. The chamber support is provided with heating elements.Type: GrantFiled: January 2, 2002Date of Patent: February 15, 2011Assignee: Clondiag Chip Technologies GmbHInventors: Ralf Ehricht, Thomas Ellinger, Jens Tuchscherer, Eugen Ermantraut, Siegfried Poser, Torsten Schulz
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Publication number: 20110014606Abstract: A device comprising a rigid substrate, a flexible cover element at least partially covering the substrate, a first structure formed in the substrate, adapted for accommodating liquids and adapted for releasing contents of one or more cells, spores, or viruses, the contents including the target molecules, a second structure formed in the substrate, adapted for accommodating liquids and comprising at least one binding member adapted for capturing the target molecules and for determining a value indicative of the presence and/or amount of the target molecules, a micro fluidic network interconnecting at least the first structure and the second structure, and an actuator member adapted for effecting a fluid flow between the first structure and the second structure by pressing the flexible cover element against the substrate to selectively close a portion of the micro fluidic network.Type: ApplicationFiled: November 6, 2007Publication date: January 20, 2011Applicant: CLONDIAG GMBHInventors: Katrin Steinmetzer, Eugen Ermantraut, Torsten Schulz, Thomas Kaiser
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Publication number: 20100255473Abstract: A device comprising a rigid substrate, a flexible cover element at least partially covering the substrate, a first structure formed in the substrate, adapted for accommodating liquids and adapted for releasing contents of one or more cells, spores, or viruses, the contents including the target molecules, a second structure formed in the substrate, adapted for accommodating liquids and comprising at least one binding member adapted for capturing the target molecules and for determining a value indicative for the presence and/or amount of the target molecules, a microfluidic network interconnecting at least the first structure and the second structure, and an actuator member adapted for effecting a fluid flow between the first structure and the second structure by pressing the flexible cover element against the substrate to selectively close a portion of the microfluidic network.Type: ApplicationFiled: July 23, 2008Publication date: October 7, 2010Inventors: Eugen Ermantraut, Thomas Kaiser, Torsten Schulz, Katrin Steinmetzer, Thomas Ullrich
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Publication number: 20100179068Abstract: A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte.Type: ApplicationFiled: May 5, 2008Publication date: July 15, 2010Applicant: CLONDIAG GMBHInventors: Thomas Kaiser, Klaus Peter Möbius, Torsten Schulz, Thomas Uhlig, Alexander Von Schenk Zu Schweinsberg, Eugen Ermantraut, Jens Tuchscheerer
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Publication number: 20100092683Abstract: A dispenser device (100) for dispensing a substance (101) onto a substrate (102), the dispenser device (100) comprising a gripper unit (103) adapted for gripping a container (104) including the substance (101), a first motion mechanism (116, 117) adapted for moving the gripper unit (103) and the substrate (102) relative to each other within a planar region (106), and a second motion mechanism (115, 201 and 209) adapted for moving the gripper unit (103) and the substrate (102) relative to each other in a direction (108) essentially perpendicular to the planar region (106) to thereby dispense the substance (101) to a surface portion (109) of the substrate (102), wherein the first motion mechanism (115) and the second motion mechanism (116, 117) are decoupled from one another.Type: ApplicationFiled: September 24, 2007Publication date: April 15, 2010Applicant: CLONDIAG GMBHInventors: Eugen Ermantraut, Torsten Schulz, Jaochim Fischer, Daniel Weicherding, Siegfried Poser, Matthias Kirst
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Publication number: 20090082219Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.Type: ApplicationFiled: November 6, 2006Publication date: March 26, 2009Applicant: CLONDIAG GMBHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
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Publication number: 20090079963Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or the second surface.Type: ApplicationFiled: November 6, 2006Publication date: March 26, 2009Applicant: CLONDIAG GMBHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Publication number: 20080207461Abstract: The present invention relates to devices for the simultaneous performance of microarray experiments for detecting specific interactions between probe and target molecules in a microtiter plate as well as to methods for manufacturing such devices. Furthermore, the present invention relates to the use of such devices in a method for qualitatively and/or quantitatively detecting specific interactions between probe and target molecules.Type: ApplicationFiled: November 9, 2005Publication date: August 28, 2008Applicant: Clondiag Chip Technologies GMBHInventors: Eugen Ermantraut, Torsten Schulz, Anke Woestemeyer
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Publication number: 20080108512Abstract: The present invention relates to methods for the site-specific synthesis of biopolymers such as nucleic acids or peptides and their respective derivatives on solid supports, wherein the local discrimination of the synthesis is performed by using masks that guide aqueous activating reagents for cleaving off protecting groups to predetermined regions on the support.Type: ApplicationFiled: November 25, 2005Publication date: May 8, 2008Applicant: CLONDIAG CHIP TECHNOLOGIES GMBHInventors: Thomas Ellinger, Eugen Ermantraut, Nancy Hoizhey, Frank Plenz, Torsten Schulz, Jens Tuchscheerer, Daniel Weicherding
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Publication number: 20070254372Abstract: The invention relates to devices and methods for the detection of specific interactions between probe and target molecules. In particular, the invention relates to methods for the qualitative and/or quantitative detection of targets, including: introducing a sample containing targets into a reaction chamber formed between a first surface of the device and a second surface of a device, which is preferably located opposite to the first surface, wherein the distance between the first and the second surface is variable; and detecting the targets.Type: ApplicationFiled: November 6, 2006Publication date: November 1, 2007Inventors: Ralf Bickel, Alexandra Dworrak, Thomas Ellinger, Eugen Ermantraut, Torsten Schulz, Thomas Ullrich
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Patent number: D629907Type: GrantFiled: May 27, 2009Date of Patent: December 28, 2010Assignee: Clondiag GmbHInventors: Horst Boessneck, Eugen Ermantraut, Thomas Kaiser, Torsten Schulz
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Patent number: D633209Type: GrantFiled: May 27, 2009Date of Patent: February 22, 2011Assignee: Clondiag GmbHInventors: Horst Boessneck, Eugen Ermantraut, Thomas Kaiser, Torsten Schulz
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Patent number: D641477Type: GrantFiled: November 30, 2010Date of Patent: July 12, 2011Assignee: Clondiag GmbHInventors: Horst Boessneck, Eugen Ermantraut, Thomas Kaiser, Torsten Schulz