Patents by Inventor Eugene A. Sprague

Eugene A. Sprague has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of coating an intravascular stent with an endothelial cell adhesive five amino acid peptide
    Patent number: 6140127
    Abstract: Endothelial cell attachment to an intravascular stent is promoted by coating the stent with an endothelial cell specific adhesion peptide. Coating is preferably carried out by activating the intravascular stent using plasma glow discharge, applying on the stent a layer or plurality of layers of a polymer such as poly(2-hydroxyethylmethacrylate), applying a tresylation solution containing pyridine and tresyl chloride, and applying a five amino acid peptide having the sequence glycine-arginine-glutamic acid-aspartic acid-valine.
    Type: Grant
    Filed: February 18, 1998
    Date of Patent: October 31, 2000
    Assignee: Cordis Corporation
    Inventor: Eugene A. Sprague