Patents by Inventor Eugene Berezikov

Eugene Berezikov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MiRNA and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated BRAF pathway
    Patent number: 10583149
    Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with melanoma or a disease or a condition associated with activated BRAF pathway.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: March 10, 2020
    Assignees: INTERA TECHNOLOGIES B.V., KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN
    Inventors: Eugene Berezikov, Jos Bernard Poell, Willemijn Maria Gommans, Rick Jan van Haastert, Andreas Alphons F. L. van Puijenbroek, Roeland Quirinus Jozef Schaapveld, Gregoire Pierre Andre Prevost
  • Combination for use in treating diseases or conditions associated with melanoma, or treating diseases or conditions associated with activated B-raf pathway
    Patent number: 10201556
    Abstract: The invention relates to the therapeutic use of a combination in a disease and condition associated with melanoma or a disease or a condition associated with activated BRAF pathway.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: February 12, 2019
    Assignee: INTERNA TECHNOLOGIES B.V.
    Inventors: Rick Jan van Haastert, Petronella Innocentia van Noort, Grégoire Pierre André Prevost, Willemijn Maria Gommans, Roeland Quirinus Jozef Schaapveld, Matheus Maria De Gunst, Iman Johannes Schultz, Eugene Berezikov
  • MiRNA for treating diseases and conditions associated with neo-angiogenesis
    Patent number: 10023868
    Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with neo-angiogenesis.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: July 17, 2018
    Assignee: INTERNA TECHNOLOGIES B.V.
    Inventors: Sanne Weijzen, Roeland Quirinus Jozef Schaapveld, Meriem Bourajjaj, Rick Jan Van Haastert, Arjan Willem Griffioen, Judith Rosina Van Beijnum, Edwin Pieter Johan Gerard Cuppen, Eugene Berezikov, Andreas Alphons Franciscus Ludovicus Van Puijenbroek, Willemijn Maria Gommans, Negar Babae, Petronella Innocentia Van Noort
  • MiRNA and its Diagnostic and Therapeutic Uses in Diseases or Conditions Associated with Melanoma, or in Diseases or Conditions Associated with Activated BRAF Pathway
    Publication number: 20170304348
    Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with melanoma or a disease or a condition associated with activated BRAF pathway.
    Type: Application
    Filed: June 16, 2017
    Publication date: October 26, 2017
    Applicants: INTERNA TECHNOLOGIES B.V., KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN
    Inventors: Eugene Berezikov, Jos Bernard Poell, Willemijn Maria Gommans, Rick Jan van Haastert, Andreas Alphons F.L. van Puijenbroek, Roeland Quirinus Jozef Schaapveld, Gregoire Pierre Andre Prevost
  • MiRNA and its diagnostic and therapeutic uses in diseases or conditions associated with melanoma, or in diseases or conditions associated with activated BRAF pathway
    Patent number: 9682095
    Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with melanoma or a disease or a condition associated with activated BRAF pathway.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: June 20, 2017
    Assignee: INTERNA TECHNOLOGIES B.V.
    Inventors: Eugene Berezikov, Jos Bernard Poell, Willemijn Maria Gommans, Rick Jan van Haastert, Andreas Alphons F. L. van Puijenbroek, Roeland Quirinus Jozef Schaapveld, Gregoire Pierre Andre Prevost
  • BIOMARKER FOR COLORECTAL CANCER
    Publication number: 20170130277
    Abstract: Methods of diagnosing colorectal cancer and precursors thereof using miRNA biomarkers are disclosed, together with kits and devices for detecting the biomarkers, and uses of the biomarkers. The biomarkers described are reliably detected in stool and demonstrate significantly different expression levels in colorectal cancer patients when compared to colorectal cancer negative patients.
    Type: Application
    Filed: June 19, 2015
    Publication date: May 11, 2017
    Applicants: STICHTING VU-VUMC, INTERNA TECHNOLOGIES B.V.
    Inventors: Gerrit Albert MEIJER, Begoña DIOSDADO, Lisette M. TIMMER, Edwin Pieter Johan Gerard CUPPEN, Eugene BEREZIKOV, Francesco CERISOLI, Roeland Quirinus Jozef SCHAAPVELD
  • MIRNA FOR TREATING DISEASES AND CONDITIONS ASSOCIATED WITH NEO-ANGIOGENESIS
    Publication number: 20160333353
    Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with neo-angiogenesis.
    Type: Application
    Filed: August 3, 2016
    Publication date: November 17, 2016
    Applicant: INTERNA TECHNOLOGIES B.V.
    Inventors: Sanne WEIJZEN, Roeland Quirinus Jozef SCHAAPVELD, Meriem BOURAJJAJ, Rick Jan VAN HAASTERT, Arjan Willem GRIFFIOEN, Judith Rosina VAN BIEJNUM, Edwin Pieter Johan Gerard CUPPEN, Eugene BEREZIKOV, Andreas Alphons Franciscus Ludovicus VAN PIUJENBROEK, Willemijn Maria GOMMANS, Negar BABAE, Petronella Innocentia VAN NOORT
  • MiRNA for treating diseases and conditions associated with neo-angiogenesis
    Patent number: 9441222
    Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with neo-angiogenesis.
    Type: Grant
    Filed: July 2, 2013
    Date of Patent: September 13, 2016
    Assignee: INTERNA TECHNOLOGIES B.V.
    Inventors: Sanne Weijzen, Roeland Quirinus Jozef Schaapveld, Meriem Bourajjaj, Rick Jan Van Haastert, Arjan Willem Griffioen, Judith Rosina Van Biejnum, Edwin Pieter Johan Gerard Cuppen, Eugene Berezikov, Andreas Alphons Franciscus Ludovicus Van Piujenbroek, Willemijn Maria Gommans, Negar Babae, Petronella Innocentia Van Noort
  • Combination for use in treating diseases or conditions associated with melanoma, or treating diseases or conditions associated with activated B-raf pathway
    Publication number: 20150297626
    Abstract: The invention relates to the therapeutic use of a combination in a disease and condition associated with melanoma or a disease or a condition associated with activated BRAF pathway.
    Type: Application
    Filed: November 6, 2013
    Publication date: October 22, 2015
    Applicant: InteRNA Technologies B.V.
    Inventors: Rick Jan van Haastert, Petronella Innocentia van Noort, Grégoire Pierre André Prevost, Willemijn Maria Gommans, Roeland Quirinus Jozef Schaapveld, Matheus Maria De Gunst, Iman Johannes Schultz, Eugene Berezikov
  • DIAGNOSTIC PORTFOLIO AND ITS USES
    Publication number: 20150152499
    Abstract: A diagnostic portfolio comprising or consisting of isolated nucleic acid molecules, their complement and/or fragments thereof, said nucleic acid molecules, complements, equivalents and/or fragments thereof being represented by sequences comprising or consisting of sequences having at least 80% of sequence identity with SEQ ID NO:1-92, or 49-140 or derived thereof (i.e. groups a), b), c), d), e), f), g), h), i) or j) or subgroups thereof) and their uses.
    Type: Application
    Filed: July 3, 2013
    Publication date: June 4, 2015
    Applicant: InteRNA Technologies B.V.
    Inventors: Anton Jan Van Zonneveld, Jacques Duijs, Johan Kuiper, Thijs Jan Zweers, Johan Wouter Jukema, Eugene Berezikov
  • NUCLEIC ACID MOLECULES AND COLLECTIONS THEREOF, THEIR APPLICATION AND MODIFICATION
    Publication number: 20150152416
    Abstract: The invention provides a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) according to the invention or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof.
    Type: Application
    Filed: November 24, 2014
    Publication date: June 4, 2015
    Applicant: KONINKLIJKE NEDERLANDSE AKADEMIA VAN WETENSCHAPPEN
    Inventors: Ronald H. A. PLASTERK, Eugene BEREZIKOV, Edwin Pieter CUPPEN
  • Nucleic acid molecules and collections thereof, their application and modification
    Patent number: 8895720
    Abstract: The invention provides a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) according to the invention or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: November 25, 2014
    Assignee: Koninklijke Nederlandse Akademie van Wetenschappen
    Inventors: Ronald H. A. Plasterk, Eugene Berezikov, Edwin Pieter Cuppen
  • MiRNA for Treating Diseases and Conditions Associated with Neo-angiogenesis
    Publication number: 20140005251
    Abstract: The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with neo-angiogenesis.
    Type: Application
    Filed: July 2, 2013
    Publication date: January 2, 2014
    Applicant: InteRNA Technologies B.V.
    Inventors: Sanne WEIJZEN, Roeland Quirinus Jozef SCHAAPVELD, Meriem BOURAJJAJ, Rick Jan VAN HAASTERT, Arjan Willem GRIFFIOEN, Judith Rosina VAN BEIJNUM, Edwin Pieter Johan Gerard CUPPEN, Eugene BEREZIKOV, Andreas Alphons Franciscus Ludovicus VAN PUIJENBROEK, Willemijn Maria GOMMANS, Negar BABAE, Petronella Innocentia VAN NOORT
  • SMALL RNA MOLECULES, PRECURSORS THEREOF, MEANS AND METHODS FOR DETECTING THEM, AND USES THEREOF IN TYPING SAMPLES
    Publication number: 20130190379
    Abstract: The invention is related to small RNA molecules, precursors thereof and methods for detecting such molecules. The invention is in particular concerned with differentially expressed small RNA molecules and precursors thereof. Various collections of small RNA molecules, precursors thereof and collections of probe and primers that can be used to detect small RNA molecules, precursors thereof are provided. Further provided are diagnostic test based on this differential expression. Also provided are therapeutic applications using one or more of the members of the presented collections.
    Type: Application
    Filed: July 7, 2008
    Publication date: July 25, 2013
    Inventors: Edwin Pieter Johan Cuppen, Gerrit Albert Meijer, Eugene Berezikov, Maria Begona Diosdado Calvo
  • Nucleic acid molecules and collections thereof, their application and modification
    Patent number: 8362230
    Abstract: The invention provides a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) according to the invention or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof.
    Type: Grant
    Filed: January 10, 2007
    Date of Patent: January 29, 2013
    Assignee: Koninklijke Nederlandse Akademie van Wetenschappen
    Inventors: Eugene Berezikov, Edwin P. J. G. Cuppen
  • Nucleic acid molecules and collections thereof, their application and Identification
    Publication number: 20110136891
    Abstract: Provided is a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) as disclosed herein or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides new nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof.
    Type: Application
    Filed: December 23, 2010
    Publication date: June 9, 2011
    Applicant: Koninklijke Nederlandse Akademie van Wetenschappen
    Inventors: Ronald H.A. Plasterk, Eugene Berezikov, Edwin P.J.G. Cuppen
  • Nucleic Acid molecules and Collections Thereof, Their Application and Modification
    Publication number: 20100035760
    Abstract: The invention provides a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) according to the invention or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof.
    Type: Application
    Filed: January 10, 2007
    Publication date: February 11, 2010
    Inventors: Ronald H.A. Plasterk, Eugene Berezikov, Edwin P.J.G. Cuppen
  • Nucleic Acid Molecules and Collections Thereof, Their Application and Identification
    Publication number: 20090215865
    Abstract: The invention provides a method for characterising a sample comprising nucleic acid derived from a cell. The method comprises determining whether a sample comprises at least a minimal sequence of at least one new microRNA (miRNA) according to the invention or a mammalian ortholog thereof and characterizing the sample on the basis of the presence or absence of the miRNA. The invention further provides new nucleic acid molecules and collections thereof and their use in therapeutic and diagnostic applications. The invention furthermore provides a method for identifying a miRNA molecule or a precursor molecule thereof.
    Type: Application
    Filed: January 10, 2006
    Publication date: August 27, 2009
    Inventors: Ronald H.A. Plasterk, Eugene Berezikov, Edwin P.J.G. Cuppen