Patents by Inventor Eugene Cruz Amparo

Eugene Cruz Amparo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Electrophilic peptide analogs as inhibitors of trypsin-like enzymes
    Patent number: 6060462
    Abstract: This invention relates to electrophilic dipeptide analogs conjugated to an N,N-disubstituted .alpha.-amino acid as inhibitors of trypsin-like serine protease enzymes.
    Type: Grant
    Filed: August 1, 1997
    Date of Patent: May 9, 2000
    Assignee: DuPont Pharmaceuticals Company
    Inventors: Robert Anthony Galemmo, Jr., Matthew Mark Abelman, Eugene Cruz Amparo, John Matthew Fevig, Robert Madara Knabb, William Henry Miller, Gregory James Pacofsky, Patricia Carol Weber, Joseph Cacciola
  • Boronic acid and ester inhibitors of thrombin
    Patent number: 5698538
    Abstract: Novel boronic acid and ester and carboxyl-modified amino acid compounds of the Formula I, which are inhibitors of trypsin-like enzymes, are disclosed :R.sup.1 --Z--CHR.sup.2 --A,where R.sup.1, Z, R.sup.2 arid A are defined within.
    Type: Grant
    Filed: July 26, 1996
    Date of Patent: December 16, 1997
    Assignee: The DuPont Merck Pharmaceutical Company
    Inventors: Eugene Cruz Amparo, William Henry Miller, Gregory James Pacofsky, John Wityak, Patricia Carol Weber, John Jonas Vytautas Duncia, Joseph Basil Santella, III