Abstract: The present disclosure pertains to a system configured to enhance deep sleep in a subject during positive airway pressure therapy. A pressure generator is configured to generate a pressurized flow of breathable gas for delivery to an airway of the subject. Sensors are configured to generate output signals conveying information related to breathing of the subject. One or more hardware processors are configured to cause the pressure generator to generate the pressurized flow of breathable gas in accordance with a positive airway pressure therapy regime based on the information in the output signals; determine sleep stages of the subject based on the information in the output signals; and responsive to the sleep stages indicating the subject is in deep sleep, cause the pressure generator to adjust the pressurized flow of breathable gas to deliver a stimulus to the subject, the stimulus configured to enhance deep sleep in the subject.

Abstract: A method for the concurrent treatment of obstructive sleep apnea and hypertension in a patient comprises providing a flow of treatment gas to the airway of the patient in accordance with a first set of flow parameters. Determining that the patient has achieved stable breathing while receiving the provided flow of treatment gas in accordance with the first set of parameters. Determining a set of target patient breath parameters from breath data collected from the patient. Adjusting the flow of treatment gas to a different set of flow parameters. Determining that the new patient breath data, collected from the patient, accords with the target patient breath parameters and providing the flow of treatment gas to the patient in accordance with the different set of flow parameters. The target patient breath parameters include a target tidal volume of the patient which is greater than a first tidal volume of the patient.

Abstract: Concurrent treatment of obstructive sleep apnea and hypertension in a patient, via a pressure generating system, includes providing a flow of treatment gas to an airway of a patient in accordance with an initial set of flow parameters with respect to an obstructive sleep apnea mode. Responsive to determining that the patient has achieved stable breathing while receiving the flow of treatment gas, the flow parameters are increased above the initial set of flow parameters with respect to a hyper-ventilation mode. The flow of treatment gas is then provided to the airway of the patient in accordance with the increased flow parameters for a predetermined period of time. The increased flow parameters are configured to bring the patient's breath into accordance with target patient breath parameters configured to inflate the patient's lungs beyond a threshold for activating pulmonary stretch receptors of the airway of the patient.

Abstract: Concurrent treatment of obstructive sleep apnea and hypertension in a patient, via a pressure generating device, includes providing a flow of treatment gas to an airway of a patient in accordance with an initial set of flow parameters with respect to an obstructive sleep apnea mode. Responsive to determining that the patient has achieved stable breathing while receiving the flow of treatment gas, the flow parameters are increased above the initial set of flow parameters with respect to a hyper-ventilation mode. The flow of treatment gas is then provided to the airway of the patient in accordance with the increased flow parameters for a predetermined period of time. The increased flow parameters are configured to bring the patient's breath into accordance with target patient breath parameters configured to inflate the patient's lungs beyond a threshold for activating pulmonary stretch receptors of the airway of the patient.

Abstract: Concurrent treatment of obstructive sleep apnea and hypertension in a patient, via a pressure generating device, includes providing a flow of treatment gas to an airway of a patient in accordance with an initial set of flow parameters with respect to an obstructive sleep apnea mode. Responsive to determining that the patient has achieved stable breathing while receiving the flow of treatment gas, the flow parameters are increased above the initial set of flow parameters with respect to a hyper-ventilation mode. The flow of treatment gas is then provided to the airway of the patient in accordance with the increased flow parameters for a predetermined period of time. The increased flow parameters are configured to bring the patient's breath into accordance with target patient breath parameters configured to inflate the patient's lungs beyond a threshold for activating pulmonary stretch receptors of the airway of the patient.

Abstract: The present invention relates to a method for re-synchronizing a breathing pattern of a patient (16) suffering from ataxic breathing, the method including the steps of monitoring the breathing pattern of the patient (16) during sleep; detecting whether the monitored breathing pattern includes an ataxic breathing episode; and if an ataxic breathing episode is detected, ventilating the patient (16) and eliminating a spontaneous breathing of the patient (16) for a predetermined first period of time (?t1) by providing a flow of breathing gas (14) to an airway of the patient (16) with a volume of the breathing gas (14) provided per minute being above an individual-related threshold value of the patient (16).

Abstract: There is provided a control unit (100) for use with a respiratory assist device (102) that assists a subject (104) with respiration. The control unit (100) configured to detect a time at which delivery of an inhalable therapy to the subject (104) is manually triggered on an inhalable therapy device (106). The control unit (100) is also configured to detect whether the subject (104) has fallen asleep and, on detecting that the subject (104) has fallen asleep, control the inhalable therapy device (106) to automatically trigger delivery of the inhalable therapy to the subject (104) at least a predefined length of time following the detected time at which delivery of the inhalable therapy to the subject (104) is manually triggered.

Abstract: Sleep related conditions of a subject are monitored and/or diagnosed based on both sleep quality and apnea hypopnea index. A first sleep test is performed in which a sleep quality of the subject and an apnea-hypopnea index are determined. A determination is made as to whether results of the first sleep test meet a first condition based on both the sleep quality and apnea-hypopnea index of the subject associated with the first sleep test. Responsive to the results of the first sleep test failing to meet the first condition, a recommendation of a treatment for the subject is provided. An efficacy of the treatment is confirmed in a second sleep test involving the treatment by determining whether results of the second sleep test meet the first condition based on both the sleep quality and apnea-hypopnea index of the subject associated with the second sleep test.

Abstract: The present disclosure pertains to a system configured to enhance deep sleep in a subject during positive airway pressure therapy. A pressure generator is configured to generate a pressurized flow of breathable gas for delivery to an airway of the subject. Sensors are configured to generate output signals conveying information related to breathing of the subject. One or more hardware processors are configured to cause the pressure generator to generate the pressurized flow of breathable gas in accordance with a positive airway pressure therapy regime based on the information in the output signals; determine sleep stages of the subject based on the information in the output signals; and responsive to the sleep stages indicating the subject is in deep sleep, cause the pressure generator to adjust the pressurized flow of breathable gas to deliver a stimulus to the subject, the stimulus configured to enhance deep sleep in the subject.

Abstract: A method for the concurrent treatment of obstructive sleep apnea and hypertension in a patient comprises providing a flow of treatment gas to the airway of the patient in accordance with a first set of flow parameters. Determining that the patient has achieved stable breathing while receiving the provided flow of treatment gas in accordance with the first set of parameters. Determining a set of target patient breath parameters from breath data collected from the patient. Adjusting the flow of treatment gas to a different set of flow parameters. Determining that the new patient breath data, collected from the patient, accords with the target patient breath parameters and providing the flow of treatment gas to the patient in accordance with the different set of flow parameters. The target patient breath parameters include a target tidal volume of the patient which is greater than a first tidal volume of the patient.

Abstract: Sleep related conditions of a subject are monitored and/or diagnosed based on both sleep quality and apnea hypopnea index. A first sleep test is performed in which a sleep quality of the subject and an apnea-hypopnea index are determined. A determination is made as to whether results of the first sleep test meet a first condition based on both the sleep quality and apnea-hypopnea index of the subject associated with the first sleep test. Responsive to the results of the first sleep test failing to meet the first condition, a recommendation of a treatment for the subject is provided. An efficacy of the treatment is confirmed in a second sleep test involving the treatment by determining whether results of the second sleep test meet the first condition based on both the sleep quality and apnea-hypopnea index of the subject associated with the second sleep test.

Abstract: A method for the concurrent treatment of obstructive sleep apnea and hypertension in a patient, the method comprises: a) providing a flow of treatment to an airway of the patient in accordance with an initial set of flow parameters; b) determining that the patient has achieved stable breathing while receiving the provided flow of treatment gas in accordance with the initial set of parameters; c) increasing the flow parameters; d) providing the flow of treatment gas to the airway of the patient in accordance with the increased flow parameters until it is determined that a predetermined period of time has elapsed; e) further increasing the flow parameters; and f) providing the flow of treatment gas to the airway of the patient in accordance with the further increased flow parameters for a predetermined time.

Abstract: The present invention relates to a method for re-synchronizing a breathing pattern of a patient (16) suffering from ataxic breathing, the method including the steps of monitoring the breathing pattern of the patient (16) during sleep; detecting whether the monitored breathing pattern includes an ataxic breathing episode; and if an ataxic breathing episode is detected, ventilating the patient (16) and eliminating a spontaneous breathing of the patient (16) for a predetermined first period of time (?t1) by providing a flow of breathing gas (14) to an airway of the patient (16) with a volume of the breathing gas (14) provided per minute being above an individual-related threshold value of the patient (16).

Abstract: A pressure support system includes a gas flow generator; a patient interface device structured to be secured to a patient; a gas delivery conduit structured to couple the gas flow generator to the patient interface device; and a passive noise system provided on at least one of the gas flow generator, the patient interface device, and the gas delivery conduit, the passive noise system being structured to utilize a flow of gas to alter a base audible output of the pressure support system.

Abstract: The invention of the present application relates to an apparatus to aid in administering inhaled pharmaceutical aerosol to a patient. The apparatus is used in conjunction with an aerosol delivery device. The apparatus comprises steps on the top and bottom of the apparatus, which when used aid the patient causes mandibular advancement, and opening of the mouth, causing opening of patient's airway, resulting in improved aerosol lung deposition. The invention also relates to a method of using such apparatus in a combination with an aerosol delivery device or a system, and to the mouthpiece of said apparatus.

Abstract: An oral appliance (1) is provided for the treatment of snoring and obstructive sleep apnea. The oral appliance (1) includes an upper tray (10) adaptable to conform to a user's maxillary dentition and a plurality of lower trays (40), each of the lower trays (40) adaptable to conform to the user's mandibular dentition. At least some of the lower trays (40) are structured to engage the upper tray (10), each of the lower trays (40) are structured to impart a different fixed amount of mandibular advancement.

Abstract: A method for triaging a respondent includes: providing a quality of life related query to the respondent; receiving a response to the query; determining the response was indicative of a person potentially suffering from disorder sleep; providing information regarding disorder sleep; providing a demographic related query; receiving a response to the demographic related query; determining a particular demographic group for which the respondent should be associated; providing a symptom related query based on the particular demographic group; receiving a response to the symptom related query; determining the response was indicative that the respondent suffers from the symptom; determining a disease that corresponds to the symptom; providing information regarding the disease; determining the respondent's location; and providing information related to a sleep expert near the respondent's location.

Abstract: A method for selecting a device adapted to treat disordered breathing in a patient with one or more comorbid diseases is provided. More particularly, a method for reducing a potential group of patient interface devices adapted to treat disordered breathing of a patient to an optimized group, includes: prescreening the patient; determining a measure of a comorbidity of the patient from the prescreening; comparing the measure of the comorbidity to a corresponding predetermined threshold; and determining the optimized group from the potential group. The optimized group may include a reduced number of devices from which a particular device is then selected or may include only a single particular device.

Abstract: Systems and methods to treat obstructive sleep apnea draw soft tissue of the front of the neck of the subject, in particular at or near the oropharynx, into a cavity by applying negative pressure. The opening of the cavity is formed by a rim of a body that is configured to be engaged, externally, with a medial portion of the anterior side of the neck such that engagement between the rim and the neck forms a chamber that can be sealed from atmospheric pressure. Movement of the soft tissue may thus reduce temporary airway obstruction.

Abstract: A patient interface device that includes a body portion comprising a pair of arms and a chin support. A first end portion of each arm in the pair of arms is coupled to an opposite end of the chin support. The chin support is adapted to be disposed under the mandible responsive to the patient interface device being donned by a user. At least one headgear attachment element is provided on each arm in the pair of arms. A circuit portion is provided at a second end portion of each arm in the pair of arm. A patient interface portion is coupled to the circuit portion.