Patents by Inventor Eugene R. Wagner

Eugene R. Wagner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4857663
    Abstract: N-(3-Dialkylamino-2-propenylidene)-N-alkylalkanaminium salts substituted in the 2-position with an ether or thioether and having the formula ##STR1## are active as hypoglycemic agents.
    Type: Grant
    Filed: November 16, 1988
    Date of Patent: August 15, 1989
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Eugene R. Wagner, Donald P. Matthews, Charlotte L. Barney
  • Patent number: 4788335
    Abstract: N-(3-Dialkylamino-2-propenylidene)-N-alkylalkanaminium salts substituted in the 2-position with an ether or thioether and having the formula ##STR1## are active as hypoglycemic agents.
    Type: Grant
    Filed: October 20, 1987
    Date of Patent: November 29, 1988
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Eugene R. Wagner, Donald P. Matthews, Charlotte L. Barney
  • Patent number: 4584379
    Abstract: 4-[(4-Isoquinolinylmethyl)amino]benzoic acid derivatives useful as selective thromboxane synthetase inhibitors are described herein. The compounds are obtained from the appropriate 4-isoquinolinecarboxylic acid derivative and an aminobenzoic acid derivative. This gives the corresponding Schiff base which is then reduced to give the desired compounds.
    Type: Grant
    Filed: January 22, 1985
    Date of Patent: April 22, 1986
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventor: Eugene R. Wagner
  • Patent number: 4533677
    Abstract: N-(3-Dialkylamino-2-propenylidene)-N-alkylalkanaminium salts substituted in the 2-position with an ether or thioether and having the formula ##STR1## are active as hypoglycemic agents.
    Type: Grant
    Filed: May 16, 1983
    Date of Patent: August 6, 1985
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Eugene R. Wagner, Charlotte L. Barney, Donald P. Matthews
  • Patent number: 4286090
    Abstract: Tetrazolobenzotriazine compounds such as 7-chlorotetrazolo[4,5-C][1,2,3]benzotriazine are prepared by the reaction of the corresponding substituted 5-(2-aminophenyl)tetrazole with nitrous acid. These new compounds are useful as initiating explosives, propellants, and chemical blowing agents.
    Type: Grant
    Filed: February 15, 1980
    Date of Patent: August 25, 1981
    Assignee: The Dow Chemical Company
    Inventors: Thomas C. Britton, Eugene R. Wagner
  • Patent number: 4263320
    Abstract: Hypoglycemic phenylpropynylamino benzoic acids and the pharmaceutically-acceptable salts thereof, a method for lowering serum sugars and hypoglycemic compositions useful for the treatment of diabetes.
    Type: Grant
    Filed: June 4, 1979
    Date of Patent: April 21, 1981
    Assignee: The Dow Chemical Company
    Inventors: Donald P. Matthews, Eugene R. Wagner, Roger D. McDermott
  • Patent number: 4248389
    Abstract: A novel container sorting and handling system is provided for sorting a plurality of diverse types of containers into preselected types for either reuse, reclamation or disposal depending upon the type of container. The sorting system comprises a housing having a sorting station defined therein and an infeed conveyor for sequentially and individually transporting containers to the sorting station. At the sorting station the individual containers are rotated by a roller in order to bring the UPC Code, bar code or other code on each container into alignment with an optical scanner at the sorting station. The optical scanner produces an output signal representative of the bar code and this is in turn fed to a computer which compares the signal from the optical scanner with a plurality of prestored values in the computer. As a result of this comparison, the computer generates an output signal representative of the type of container at the sorting station.
    Type: Grant
    Filed: January 15, 1979
    Date of Patent: February 3, 1981
    Inventors: Fremont G. Thompson, Lewis P. Vogel, Eugene R. Wagner
  • Patent number: 4218475
    Abstract: Substituted or unsubstituted benzylaminobenzene alkanoic or alkenoic acids are disclosed as hypolipidemic agents and especially as hypocholesterolemic agents; along with a method of use and pharmaceutical compositions thereof.
    Type: Grant
    Filed: October 26, 1978
    Date of Patent: August 19, 1980
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Donald P. Matthews, Alfred A. Renzi
  • Patent number: 4207330
    Abstract: A method for treating hyperglycemia in a mammal which comprises administering internally to said mammal a hypoglycemic amount of an arylamino benzoic acid or pharmaceutically-acceptable salt thereof, wherein aryl represents phenyl, substituted phenyl, thienyl or substituted thienyl.
    Type: Grant
    Filed: February 22, 1979
    Date of Patent: June 10, 1980
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Roger D. McDermott
  • Patent number: 4206223
    Abstract: A method for treating hyperglycemia in a mammal which comprises administering to said mammal a hyperglycemic amount of a derivative of 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid or a pharmaceutically-acceptable salt thereof.
    Type: Grant
    Filed: January 5, 1979
    Date of Patent: June 3, 1980
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Roger D. McDermott
  • Patent number: 4192884
    Abstract: Halo-substituted 4-(((thienyl)methyl)amino)benzoic acids, the corresponding esters and salts thereof, and a method for lowering serum lipid levels in mammals.
    Type: Grant
    Filed: June 12, 1978
    Date of Patent: March 11, 1980
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Donald P. Matthews
  • Patent number: 4181737
    Abstract: The compound 4-((3-methoxyphenylmethyl)amino)benzoic acid and the pharmaceutically-acceptable salts thereof used to treat hyperlipidemia, especially hypercholesterolemia, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: May 18, 1978
    Date of Patent: January 1, 1980
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Alfred A. Renzi
  • Patent number: 4178385
    Abstract: A method for treating hyperlipidemia in primates using the compound 4-((4-fluorophenylmethyl)amino)benzoic acid, a pharmaceutically-acceptable salt or an ester thereof.
    Type: Grant
    Filed: March 3, 1978
    Date of Patent: December 11, 1979
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Alfred A. Renzi
  • Patent number: 4143151
    Abstract: A method for treating hyperglycemia in a mammal which comprises administering internally to said mammal a hyperglycemic amount of an arylamino benzoic acid or pharmaceutcially-acceptable salt thereof, wherein aryl represents phenyl, substituted phenyl, thienyl or substituted thienyl.
    Type: Grant
    Filed: July 3, 1978
    Date of Patent: March 6, 1979
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Roger D. McDermott
  • Patent number: 4133890
    Abstract: This invention relates to compositions of 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid the corresponding pharmaceutically-acceptable salts and the esters thereof. The invention also relates to methods for reducing plasma lipid levels in mammals using the compounds and compositions.
    Type: Grant
    Filed: July 25, 1977
    Date of Patent: January 9, 1979
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Alfred A. Renzi, Bobbie J. Allen
  • Patent number: 4105791
    Abstract: The present invention relates to novel monocyclic and polycyclic p-cycloalkylaminobenzoic acids, the corresponding pharmaceutically-acceptable salts and the esters thereof. This invention also relates to methods for reducing plasma lipid levels, especially cholesterol and triglyceride levels, using the compounds of the present invention.
    Type: Grant
    Filed: March 22, 1976
    Date of Patent: August 8, 1978
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Donald P. Matthews
  • Patent number: 4103029
    Abstract: This invention relates to novel compounds and compositions of amino substituted arylthio-alkanoic acid, the corresponding pharmaceutically-acceptable salts and the esters thereof. The invention also relates to methods for reducing plasma lipid levels in animals using the compounds of the present invention.
    Type: Grant
    Filed: August 10, 1977
    Date of Patent: July 25, 1978
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Bobbie J. Allen
  • Patent number: 4103027
    Abstract: This invention relates to novel compounds and compositions of amino substituted arylthio-alkanoic acid, the corresponding pharmaceutically-acceptable salts and the esters thereof. The invention also relates to methods for reducing plasma lipid levels in animals using the compounds of the present invention.
    Type: Grant
    Filed: August 12, 1977
    Date of Patent: July 25, 1978
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Bobbie J. Allen
  • Patent number: 4078084
    Abstract: Novel 2-((3,5-di-tert-butyl-4-hydroxyphenyl)thio)carboxamides and compositions containing the compounds are disclosed. A method for reducing blood serum lipids using the compounds and compositions of the invention is also disclosed.
    Type: Grant
    Filed: March 4, 1977
    Date of Patent: March 7, 1978
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Larry G. Mueller
  • Patent number: 4076841
    Abstract: Novel 2-((3,5-di-tert-butyl-4-hydroxyphenyl)-thio)carboxamides and compositions containing the compounds are disclosed. A method for reducing blood serum lipids using the compounds and compositions of the invention is also disclosed.
    Type: Grant
    Filed: March 4, 1977
    Date of Patent: February 28, 1978
    Assignee: The Dow Chemical Company
    Inventors: Eugene R. Wagner, Larry G. Mueller