Abstract: An actuation assembly for a tissue recruiting device for recruiting tissue and closing a defect. The actuation assembly includes one or more control actuators operable to control the position and rotation of an actuation element coupled to a grasping device. The grasping device is configured to grasp tissue. The actuation assembly is operable by a user to deploy the grasping device via the actuation element to grasp tissue. The actuation assembly may independently deploy multiple grasping devices, such as on opposite sides of a defect. The actuation assembly may also deploy a closure mechanism configured to circumferentially surround the deployed grasping devices to close the defect.

Abstract: Powered drivers (10) for inserting an intraosseous device (160) into a bone and associated bone marrow are disclosed. Some of the powered drivers (10) may include a housing (12) having a distal end (14) and a proximal end (16); a motor (18) disposed in the housing (12); a driveshaft (34) extending outward from the distal end (14) of the housing in a direction away from the proximal end (16); a gearbox (32) coupled to the motor (18) and to the driveshaft (34) such that activation of the motor (18) causes the driveshaft (34) to rotate; and a power source (40) configured to power the motor (18). A guard member (50) may be pivotably connected to the housing (12) and movable between a protective position and a non-protective position. The guard member (50) may be configured to cover the intraosseous (10) needle assembly in the protective position and to expose the intraosseous (10) needle assembly in the non-protective position.

Abstract: A motorized actuation module actuates an endoscopic instrument. It is made up of a mounting plate able to be attached to the ulnar-palmar grasping zone of a handgrip of an endoscope, the mounting plate having an ulnar-palmar bearing surface extended by a heel extending in a direction that makes an angle of 90°±25° with respect to the perpendicular to the plane of the ulnar-palmar bearing surface. The heel includes an electromechanical sensor that delivers a control signal controlling the movement of an endoscopy instrument.

Abstract: A biopsy device comprising: a cannula comprising an elongate cannula body extending between a cannula distal end and a cannula proximal end to define a lumen, wherein the cannula comprises a cutting portion at the cannula distal end; a stylet comprising an elongate body having a stylet distal end and a stylet proximal end, the stylet being slidably disposed within the lumen, wherein the stylet comprises a tissue sampling portion. The tissue sampling portion is formed by a notch in the body of the stylet at or near the stylet distal end. The biopsy device further comprises an actuator assembly, the actuator assembly arranged to move the cannula relative to the stylet between a retracted position in which at least part of the tissue sampling portion is exposed and an extended position in which the cannula at least partly surrounds the tissue sampling portion.

Abstract: Manually driven intraosseous devices and associated methods are disclosed. The intraosseous device includes a housing and a transmission at least partially disposed within the housing. The transmission includes a first portion and a second portion. The second portion includes a manual actuator that is at least partially disposed outside of the housing. The intraosseous device also includes a penetrator assembly releasably connected to the first portion of the transmission. The transmission is configured to transmit a force, which is applied manually to the manual actuator, to the penetrator assembly to rotate the penetrator assembly relative to the housing and to drive the penetrator assembly through a bone into an intraosseous space. The manual actuator is a hand crank that is configured to be manually cranked by an operator to transfer rotational force to the first portion of the transmission.

Abstract: Manually driven intraosseous devices and associated methods are disclosed. The intraosseous device includes a housing and a transmission at least partially disposed within the housing. The transmission includes a first portion and a second portion. The second portion including a manual actuator that is at least partially disposed outside of the housing. The intraosseous device also includes a penetrator assembly releasably connected to the first portion of the transmission. The transmission is configured to transmit a force, which is applied manually to the manual actuator, to the penetrator assembly to rotate the penetrator assembly relative to the housing and to drive the penetrator assembly through a bone into an intraosseous space. The manual actuator is a pull chord and the force is configured to be applied by an operator to a first end of the pull chord to unwind the pull chord and transmit the force to the penetrator assembly.

Abstract: The present disclosure includes systems, methods, and apparatuses for dispensing a volume (e.g., a volume of liquid or medication) during intraosseous infusion. In some embodiments, a resilient member is used to bias a portion of an arm towards a contracted position with a force sufficient to depress a plunger of a syringe, and a damper is used to resist movement of the portion of the arm from the extended position toward the contracted position to control a rate at which the resilient member can move the portion of the arm from the extended position toward the retracted position, and thereby limit the rate at which a volume is dispensed from the syringe. In other embodiments, a flow control valve may be used instead of a damper to limit the rate at which a volume is dispensed from the syringe.

Abstract: Provided herein is a mechanical device including a rotating spool assembly and a disposable valve assembly. The rotating spool assembly includes a hub, an arm, and a spool inserted through an opening in the arm. The rotating spool assembly can be sterilized after each use. The disposable valve assembly includes a mating stem member, a sealing member, and a flushing port member. The disposable valve assembly can be disposed of after every use. A loading member is also provided including a wire that can be formed from metal drawn out into a thin flexible thread. The loading member can be pre-formed in a helix to form coils in the wire. A release cord is provided including a braided cord with two single filaments and a plurality of beads formed along a length of the single filaments at a distal end of the braided cord.

Abstract: Powered drivers (10) for inserting an intraosseous device (160) into a bone and associated bone marrow are disclosed. Some of the powered drivers (10) may include a housing (12) having a distal end (14) and a proximal end (16); a motor (18) disposed in the housing (12); a driveshaft (34) extending outward from the distal end (14) of the housing in a direction away from the proximal end (16); a gearbox (32) coupled to the motor (18) and to the driveshaft (34) such that activation of the motor (18) causes the driveshaft (34) to rotate; and a power source (40) configured to power the motor (18). A guard member (50) may be pivotably connected to the housing (12) and movable between a protective position and a non-protective position. The guard member (50) may be configured to cover the intraosseous (10) needle assembly in the protective position and to expose the intraosseous (10) needle assembly in the non-protective position.

Abstract: A biopsy device comprising: a cannula comprising an elongate cannula body extending between a cannula distal end and a cannula proximal end to define a lumen, wherein the cannula comprises a cutting portion at the cannula distal end; a stylet comprising an elongate body having a stylet distal end and a stylet proximal end, the stylet being slidably disposed within the lumen, wherein the stylet comprises a tissue sampling portion. The tissue sampling portion is formed by a notch in the body of the stylet at or near the stylet distal end. The biopsy device further comprises an actuator assembly, the actuator assembly arranged to move the cannula relative to the stylet between a retracted position in which at least part of the tissue sampling portion is exposed and an extended position in which the cannula at least partly surrounds the tissue sampling portion.

Abstract: The present disclosure relates to a mechanical thrombectomy device that includes a catheter assembly with a basket assembly formed of a proximal hub and a distal hub; a flexible tube having a first end attached to the proximal hub and a second end attached to the distal hub; and a plurality of basket wires. The flexible tube may be laser-cut to allow for bending, elongation, and compression. The basket wires each have a first end attached to the proximal hub and a second end attached to the distal hub. The basket wires are disposed around the flexible tube and configured to expand to a preset shape. The basket assembly is attached to a distal end of a rotatable shaft. A drive assembly is configured to rotate the rotatable shaft to rotate the basket assembly. The basket assembly when rotated is configured to macerate a material proximate to the basket assembly.

Abstract: The present invention relates to a deployment handle for a prosthesis delivery device and to a delivery device including such a handle. The handle assembly facilitates the controlled release of a prosthesis from the delivery device, while ensuring that various deployment steps are performed in a particular sequential order. The handle assembly comprises a main handle and a second handle which is rotatably and/or longitudinally moveable relative to the main handle. The second handle has an initial position on the main handle such that it prevents access to, and premature manipulation of, a proximal stent release mechanism, until the stent graft has been at least partially unsheathed.

Abstract: The present disclosure includes systems, methods, and apparatuses for dispensing a volume (e.g., a volume of liquid or medication) during intraosseous infusion. In some embodiments, a resilient member is used to bias a portion of an arm towards a contracted position with a force sufficient to depress a plunger of a syringe, and a damper is used to resist movement of the portion of the arm from the extended position toward the contracted position to control a rate at which the resilient member can move the portion of the arm from the extended position toward the retracted position, and thereby limit the rate at which a volume is dispensed from the syringe. In other embodiments, a flow control valve may be used instead of a damper to limit the rate at which a volume is dispensed from the syringe.

Abstract: Provided herein is a mechanical device including a rotating spool assembly and a disposable valve assembly. The rotating spool assembly includes a hub, an arm, and a spool inserted through an opening in the arm. The rotating spool assembly can be sterilized after each use. The disposable valve assembly includes a mating stem member, a sealing member, and a flushing port member. The disposable valve assembly can be disposed of after every use. A loading member is also provided including a wire that can be formed from metal drawn out into a thin flexible thread. The loading member can be pre-formed in a helix to form coils in the wire. A release cord is provided including a braided cord with two single filaments and a plurality of beads formed along a length of the single filaments at a distal end of the braided cord.

Abstract: The present disclosure relates to a mechanical thrombectomy device that includes a catheter assembly with a basket assembly formed of a proximal hub and a distal hub; a flexible tube having a first end attached to the proximal hub and a second end attached to the distal hub; and a plurality of basket wires. The flexible tube may be laser-cut to allow for bending, elongation, and compression. The basket wires each have a first end attached to the proximal hub and a second end attached to the distal hub. The basket wires are disposed around the flexible tube and configured to expand to a preset shape. The basket assembly is attached to a distal end of a rotatable shaft. A drive assembly is configured to rotate the rotatable shaft to rotate the basket assembly. The basket assembly when rotated is configured to macerate a material proximate to the basket assembly.

Abstract: The present invention relates to a deployment handle for a prosthesis delivery device and to a delivery device including such a handle. The handle assembly facilitates the controlled release of a prosthesis from the delivery device, while ensuring that various deployment steps are performed in a particular sequential order. The handle assembly comprises a main handle and a second handle which is rotatably and/or longitudinally moveable relative to the main handle. The second handle has an initial position on the main handle such that it prevents access to, and premature manipulation of, a proximal stent release mechanism, until the stent graft has been at least partially unsheathed.