Abstract: An impact control system includes a supporting structure with gravity compensation mechanism, and a supporting bed which is supported by the supporting structure and supports an impact target. Here, the supporting structure includes an elastic element, a vertical support to which one end of the elastic element is fixed, a horizontal support to which the other end of the elastic element is fixed, and which is rotatable around a rotation axis disposed at one end of the horizontal support meeting an end of the vertical support, and a weight support part which is connected to the other end of the horizontal support and supports the supporting bed while contacting a lower surface of the supporting bed.

Abstract: A quantitative impact control and measurement system includes an impactor configured to apply an impact to a target, a control device configured to control movement of the impactor, an acceleration sensor mounted to a base of the impactor, and an impact sensor mounted to a terminal of the impactor. Here, the control device calculates an impact actually applied to the target from signals measured through the acceleration sensor and the impact sensor.

Abstract: The present disclosure relates to an apparatus and a method for manufacturing a channel-coupled scaffold. The present disclosure provides a method for manufacturing a channel-coupled scaffold, which includes: (1) a step of compressing a first elastic substrate which includes a groove on the surface of the substrate to close the groove; (2) a step of loading a scaffold composition onto the closed groove; and (3) a step of restoring the elastic substrate. The present disclosure also provides an apparatus for manufacturing a channel-coupled scaffold, which includes: a first elastic substrate which includes a groove on the surface of the substrate and onto which a scaffold composition is loaded: and a compression module which compresses the width of the groove of the elastic substrate to close it. The apparatus or method may accumulate a microchannel controlling local mass transfer, and align a collagen fiber in the scaffold at the same time.

Abstract: An impact control system includes a supporting structure with gravity compensation mechanism, and a supporting bed which is supported by the supporting structure and supports an impact target. Here, the supporting structure includes an elastic element, a vertical support to which one end of the elastic element is fixed, a horizontal support to which the other end of the elastic element is fixed, and which is rotatable around a rotation axis disposed at one end of the horizontal support meeting an end of the vertical support, and a weight support part which is connected to the other end of the horizontal support and supports the supporting bed while contacting a lower surface of the supporting bed.

Abstract: A quantitative impact control and measurement system includes an impactor configured to apply an impact to a target, a control device configured to control movement of the impactor, an acceleration sensor mounted to a base of the impactor, and an impact sensor mounted to a terminal of the impactor. Here, the control device calculates an impact actually applied to the target from signals measured through the acceleration sensor and the impact sensor.

Abstract: A neural probe structure has a probe having a microfluidic channel. The probe is inserted into an inside of a subject. A body to which the probe is fixed has a fluid entrance communicating with the microfluidic channel. A cover element is fixed to the body to cover the fluid entrance. The cover element has a connecting opening to which an external conduit is connected, and a fluid delivery channel extending such that the connecting opening and the fluid entrance are in fluid communication. A fluid fed from the external conduit flows along the fluid delivery channel, goes into the fluid entrance, and is delivered to the subject through the microfluidic channel.

Abstract: The present disclosure relates to stretching apparatus and method for aligning microfibrils. Specifically, the present disclosure provides an apparatus for aligning microfibrils along a single direction, which includes: a first elastic substrate onto which a composition containing microfibrils is loaded; and a stretching module which stretches the width of the elastic substrate. In accordance with the apparatus the present disclosure, microfibrils or cells may be aligned along a particular direction simply by pulling and then releasing the elastic substrate. The present disclosure is also useful for culturing of the aligned cells because the physiological activity of the cells can be maintained and cytotoxicity can be prevented.

Abstract: The present disclosure relates to an apparatus and a method for manufacturing a channel-coupled scaffold. The present disclosure provides a method for manufacturing a channel-coupled scaffold, which includes: (1) a step of compressing a first elastic substrate which includes a groove on the surface of the substrate to close the groove; (2) a step of loading a scaffold composition onto the closed groove; and (3) a step of restoring the elastic substrate. The present disclosure also provides an apparatus for manufacturing a channel-coupled scaffold, which includes: a first elastic substrate which includes a groove on the surface of the substrate and onto which a scaffold composition is loaded: and a compression module which compresses the width of the groove of the elastic substrate to close it. The apparatus or method may accumulate a microchannel controlling local mass transfer, and align a collagen fiber in the scaffold at the same time.

Abstract: A neural probe structure has a probe having a microfluidic channel. The probe is inserted into an inside of a subject. A body to which the probe is fixed has a fluid entrance communicating with the microfluidic channel. A cover element is fixed to the body to cover the fluid entrance. The cover element has a connecting opening to which an external conduit is connected, and a fluid delivery channel extending such that the connecting opening and the fluid entrance are in fluid communication. A fluid fed from the external conduit flows along the fluid delivery channel, goes into the fluid entrance, and is delivered to the subject through the microfluidic channel.

Abstract: The present disclosure relates to stretching apparatus and method for aligning microfibrils. Specifically, the present disclosure provides an apparatus for aligning microfibrils along a single direction, which includes: a first elastic substrate onto which a composition containing microfibrils is loaded; and a stretching module which stretches the width of the elastic substrate. In accordance with the apparatus the present disclosure, microfibrils or cells may be aligned along a particular direction simply by pulling and then releasing the elastic substrate. The present disclosure is also useful for culturing of the aligned cells because the physiological activity of the cells can be maintained and cytotoxicity can be prevented.

Abstract: A micro sensing system for real-time sensing a neurotrophic factor included in a body fluid includes a body, a neurotrophic factor channel formed in the body to allow a fluid flow therein, and a biosensor formed at the body to sense the neurotrophic factor, wherein the body fluid is extracted in a living body through the neurotrophic factor channel, and wherein the biosensor is disposed on a path of the neurotrophic factor channel to directly contact a body fluid flowing through the neurotrophic factor channel and senses a concentration of a neurotrophic factor in the body fluid.

Abstract: A neural probe array includes a probe body that is implanted into a subject, a fixture body to support a rear end of the probe body, a cladding extending in a lengthwise direction of the probe body in an upper part of the probe body, and an optical waveguide member installed on the cladding along the cladding, and the cladding is embedded in a recessed cavity formed in the upper part of the probe body. A method for manufacturing the neural probe array includes forming the cavity in an upper part of a first substrate, embedding the cladding in the cavity, forming the optical waveguide member on the cladding along the cladding, and forming the probe body by cutting the first substrate off.

Abstract: As an apparatus for manufacturing a micro lens array includes a first substrate having a plurality of cavities formed at locations corresponding to locations of the plurality of micro lenses, and a second substrate having a lower softening point than the first substrate and bonded on the first substrate to close the plurality of cavities, wherein a portion of the second substrate located on the cavities swells convexly by air trapped in the cavities expanding its volume in response to a temperature above the softening point of the second substrate being applied, to form domes corresponding to a shape of the micro lenses, and the micro lens array is cast using the second substrate having the formed domes as a mold.

Abstract: An optical stimulation probe has a probe body inserted into a subject, an electrode formed on the probe body and collecting a response signal from the subject, a light irradiator attached to the probe body and irradiating an optical signal and a reflecting surface formed on the probe body on the path of the optical signal. The reflecting surface changes the course of the optical signal irradiated from the light irradiator to the direction where the electrode faces by reflecting the optical signal. The electrode may be formed on a side portion of the probe body such that it faces a direction perpendicular to a length direction of the probe body, and the optical signal reflected by the reflecting surface may travel along a direction perpendicular to the length direction of the probe body, such that the direction where the electrode faces and the direction along which the reflected optical signal travels are parallel to each other.

Abstract: The micro probe according to an embodiment of the present disclosure includes: a probe portion made of a rigid material and serving as a portion inserted into the brain; a flexible portion connected to a distal end of the probe portion and made of a flexible material; a soluble portion coated on at least one surface of the flexible portion and made of a material which is dissolved by a solution in the cranium; and a body portion connected to the other end of the flexible portion whose one end is connected to the probe portion.

Abstract: Disclosed are an optical stimulation probe structure having a probe body inserted into a subject, a fixing body that fixes the probe body and a light radiator that transmits an optical signal to the probe body, wherein the probe body is made of an optical transmission material capable of transmitting an optical signal, such that the optical signal transmitted from the light radiator is transmitted through the probe body to the subject, and a method for manufacturing the same.

Abstract: A polymer linear actuator for a micro electro mechanical system (MEMS) and a micro manipulator for a measurement device of cranial nerve signal using the same are provided. The polymer linear actuator has first and second bodies positioned spaced apart to a distance from each other, and one or more pairs of V-type moving units connecting the first and second bodies together, wherein the moving units in pair are opposed to each other to convert a rotation motion of the respective moving units into a linear motion, thereby causing the first and second bodies to move linearly.

Abstract: The multi-selective micromanipulator has a main mover which moves linearly or rotationally with respect to an axis, an actuator which moves the main mover, a projection which is formed on the main mover, and a plurality of submovers which the projection selectively contacts depending on the movement of the main mover, wherein a selected submover is linearly moved by the projection in a direction parallel to the axis direction.

Abstract: The tactile display device of the present disclosure includes: an actuator which is movable in a vertical direction when an electric current or a pneumatic force is applied thereto; and a body made of flexible material and having a receiving unit for receiving the actuator and a fluid channel allowing a pneumatic force from an outside to be transferred to the receiving unit, wherein a membrane made of flexible material and capable of vertical displacement is attached to an upper end of the receiving unit of the body, and the actuator is coupled to a lower portion of the membrane so that the membrane and the actuator have the same vertical displacement.

Abstract: This disclosure relates to a micro manipulator having a simple structure and having high possibility of recording a biological signal of a neuron at a desired position by improving positioning resolution of an electrode disposed adjacent to a subject's brain neuron or an electrode holder attached with the electrode. The micro manipulator according to the disclosure includes: a motor which includes a shaft and a vibration portion; a mobile which is connected to the shaft so as to be movable along the shaft; and a frame which supports the motor, wherein an electrode is connected to the mobile in a direction parallel to a longitudinal direction of the shaft, and wherein when the mobile moves linearly in accordance with a vibration of the shaft due to the vibration portion, the electrode moves linearly.