Abstract: The present invention relates to a cosmetic or pharmaceutical composition for topical application, said composition comprising the combination of a crosslinked oligo(ethylene glycol) based polymer in the form of an aqueous dispersion of microgel particles and a non-crosslinked water-soluble oligo(ethylene glycol) polymer. The invention also relates to a process for preparing this composition.

Abstract: The present invention relates to a cosmetic or pharmaceutical composition for topical application, said composition comprising the combination of a crosslinked oligo(ethylene glycol) based polymer in the form of an aqueous dispersion of microgel particles and a non-crosslinked water-soluble oligo(ethylene glycol) polymer. The invention also relates to a process for preparing this composition.

Abstract: Mucoadhesive microgel compositions, which include an active agent (such as HB-EGF), are provided. Aspects of the invention include a microgel comprising a crosslinked poly(ethylene glycol) methyl ether methacrylate polymer comprising a mucoadhesive functionality. Also provided are methods of making and using the mucoadhesive microgel compositions, e.g., in therapeutic applications. In one embodiment, HB-EGF loaded mucoadhesive microgel compositions are provided, e.g., for prevention or treatment of mucositis conditions, such as therapy induced oral mucositis conditions.

Abstract: An abrasive article including a body including abrasive particles contained within a bond material, a first major surface, a second major surface, and a side surface extending between the first major surface and second major surface, and a coating overlying at least a portion of one of the first major surface or the second major surface. In an embodiment, the coating comprises at least one element selected from the group of chromium, nickel, carbon, nitrogen, tungsten, sulfur, molybdenum, iron, zinc, silicon, titanium, aluminum, zirconium, magnesium, zinc, boron, cobalt, calcium, or any combination thereof. In another embodiment, the coating comprises a cermet, a ceramic, or a combination thereof.

Abstract: An abrasive article including a body including abrasive particles contained within a bond material, a first major surface, a second major surface, and a side surface extending between the first major surface and second major surface, and a coating overlying at least a portion of one of the first major surface or the second major surface. In an embodiment, the coating comprises at least one element selected from the group of chromium, nickel, carbon, nitrogen, tungsten, sulfur, molybdenum, iron, zinc, silicon, titanium, aluminum, zirconium, magnesium, zinc, boron, cobalt, calcium, or any combination thereof. In another embodiment, the coating comprises a cermet, a ceramic, or a combination thereof.