Patents by Inventor Eva Somfai
Eva Somfai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5424327Abstract: The invention relates to novel combined compositions for combatting plant, animal and sanitarian as well as forestry, horticultural and warehouse pests. These compositions contain a pyrethroid-type insecticide as an insecticidally active ingredient and at least one fungicide inhibiting the ergosterol biosynthesis as activity-strengthening agent as well as optionally piperonylbutoxide and other additives.The advantages of the compositions according to the invention consist therein that the activity-strengthening substances used are fungicidal agents widely used and have an advantageous toxicology. The activity-strengthening agent exerts a synergistic effect together with the pyrethroid-type insecticide.The combinations according to the invention bear an outstanding importance in the protection of stored crops.Type: GrantFiled: September 9, 1994Date of Patent: June 13, 1995Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara RTInventors: Laszlo Pap, Istvan Szekely, Lajos Nagy, Andras Szego, Andrea Toth, Eva Somfai, Csaba Szantay, Lajos Novak, Laszlo Poppe
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Patent number: 5389662Abstract: The invention relates to novel combined compositions for combatting plant, animal and sanitarian as well as forestry, horticultural and warehouse pests. These compositions contain a pyrethroid-type insecticide as an insecticidally active ingredient and at least one fungicide inhibiting the ergosterol biosynthesis as activity-strengthening agent as well as optionally piperonylbutoxide and other additives.The advantages of the compositions according to the invention consist therein that the activity-strengthening substances used are fungicidal agents widely used and have an advantageous toxicology. The activity-strengthening agent exerts a synergistic effect together with the pyrethroid-type insecticide.The combinations according to the invention bear an outstanding importance in the protection of stored crops.Type: GrantFiled: May 31, 1991Date of Patent: February 14, 1995Assignee: Chinoin Gyogyszer Es Vegyeszeti Termekek Gyar Rt.Inventors: Laszlo Pap, Istvan Szekely, Lajos Nagy, Andras Szego, Andrea Toth, Eva Somfai, Csaba Szantay, Lajos Novak, Laszlo Poppe
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Patent number: 5338868Abstract: A process is disclosed for the preparation of a compound of the Formula (VI) ##STR1## wherein X is a hydrogen atom, or OH,Y is a hydrogen atom, OH or a methyl group,R.sup.2 is a CH--COOR group, or a group of the formula (XI) ##STR2## and R is a C.sub.1 to C.sub.2 alkyl group, which comprises the step of: reacting a condensed salt of the Formula (IV) ##STR3## wherein Me is Na.sup.+ or K.sup.+, with a reactive derivative of trifluoromethane-sulfonic acid of the Formula (V)F.sub.3 C--SO.sub.2 OH.The compounds of the Formula (VI) are intermediates in the preparation of penicillins and cephalosporins with antibiotic activity.Type: GrantFiled: May 24, 1991Date of Patent: August 16, 1994Assignee: Chinoin Gyogyszer- es Vegyeszeti Termekek Gyara Rt.Inventors: Karoly Ban, Annamaria Ban, Lajosne Pali, Marta Kruppa, Eva Somfai, Csaba Huszar
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Patent number: 5278309Abstract: A pure crystalline O-(2-hydroxy-3-piperidino-1-propyl) nicotinic acid amidoxime base of the Formula (Ib) ##STR1## is disclosed characterized by a melting point of 70.degree. to 73.degree. C., giving, when dissolved in an amount of 1 to 10 ml of concentrated sulfuric acid, a yellow homogeneous solution, and showing the following spectral characteristics:IR spectrum (kBr): .gamma. --O--C.dbd.N 1642 cm.sup.-1.sup.1 H-NMR spectrum (CDCL.sub.3, .delta. ppm): 1.48 m, (6H), CH.sub.2 -piperidine; 2.42 m, (6H), 3.times.CH.sub.2 --N; 3.36, br, (1H), CH--O; 4.08 m, (3H), 1--CH.sub.2, OH; 5.2, br, (2H), NH.sub.2 ; 7.30 m (1H), pyridine-5'; 7.92 m, 4', 8.62 m (1H), 6', 8.88 m, (1H), 2'.Type: GrantFiled: February 19, 1993Date of Patent: January 11, 1994Assignee: Chinoin Gyogyszar es Vegyeszeti Termekek Gyara RT.Inventors: Bela Bertok, Istvan Szekely, Angelika Thurna, Lajos Nagy, Eva Somfai, Sandor Botar, Antal Gajary, Kalman Takacs
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Patent number: 5247102Abstract: The invention relates to a process for the preparation of pure isoflavone derivatives of the general formula (I), ##STR1## wherein R stands for hydrogen or isopropyl,R.sup.2 and R.sup.3 stand for hydrogen or C.sub.1-2 alkoxy by reacting a rezorcinol-derivative of the general formula (III) ##STR2## wherein R.sup.2 and R.sup.3 are as given above with ethyl-orthoformiate of the formula (IV)(C.sub.2 H.sub.5 O).sub.3l CH (IV)in the presence of a base and optionally by alkylating the product.Type: GrantFiled: December 5, 1991Date of Patent: September 21, 1993Assignee: Chinoin Gyogyszer- es Vegyeszeti Termekek Gyara Rt.Inventors: Tamas Kallay, Gyorgy Lanyi, Laszlo Ledniczky, Lajos Imrei, Gyorgy Hoffmann, Maria Sziladi, Eva Somfai, Tibor Montay
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Patent number: 5239077Abstract: The inventions is a purer form of O-(2-hydroxy-3-piperidino-1-propyl)nicotinic acid amidoxime hydrochloride.Type: GrantFiled: November 9, 1990Date of Patent: August 24, 1993Assignee: Chinoin Gyogyszar es Vegyeszeti Termekek Gyara Rt.Inventors: Bela Bertok, Istvan Szekely, Angelika Thurna, Lajos Nagy, Eva Somfai, Sandor Bota, Antal Gajary, Kalman Takacs
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Patent number: 5235109Abstract: The invention relates to an improved, large scale process for the preparation of compounds of formula (I) ##STR1## wherein R is halogen atom or hydroxyl,R.sup.2 is hydrogen atom or hydroxyl,R.sup.3 and R.sup.4 are hydrogen or alkoxy having 1-6 carbon atoms.Type: GrantFiled: December 11, 1991Date of Patent: August 10, 1993Assignee: Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara RTInventors: Gyorgy Lanyi, Tamas Kallay, Laszlo Ledniczky, Lajos Imrei, Eva Somfai, Tibor Montay, Robert Gepesz, Valeria Denes nee Lustig, Laszlo rvai
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Patent number: 5220068Abstract: The present invention relates to a pharmaceutical composition comprising as active ingredient a compound of the Formula I ##STR1## wherein R.sup.1 stands for straight or branched chain alkyl comprising 1 to 8 carbon atoms; phenyl alkyl having 7 to 10 carbon atoms; phenyl; or cycloalkyl comprising 3 to 8 carbon atoms;R.sup.2 stands for straight or branched chain alkyl comprising 1 to 8 carbon atoms; alkyl comprising 1 to 8 carbon atoms substituted by halogen, hydroxy, alkoxy having 1 to 4 carbon atoms or by one or two phenyl groups; phenyl; or cycloalkyl having 3 to 8 carbon atoms,with the proviso that groups R.sup.1 and R.sup.2 together contain at least three carbon atoms. The invention also relates to a process for the preparation of compounds of the Formula I by methods known per se.Type: GrantFiled: January 29, 1991Date of Patent: June 15, 1993Assignee: Chinoin Gyogyszer - es Vegyeszeti Termekek Gyara Rt.Inventors: Jozsef Knoll, Antal Simay, Eva Szinnyei, Eva Somfai, Zoltan Torok, Karoly Mozsolits, Janos Bergmann
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Patent number: 5189062Abstract: ULV plant protecting arthropodicidal formulation comprising alkyl aryl polyglycol ether as further additives in addition to the active ingredient(s) dissolved in the mixture of alphatic hydrocarbons and sunflower oil. The formulation according to the invention has an initial contact angle on the plant surface of >13.degree., after 20 minutes of >6.degree. and it is often 120 minutes still at least 2.degree..Type: GrantFiled: January 28, 1992Date of Patent: February 23, 1993Assignee: Chinoin Gyogyszer -ES Vegyeszeti Termekek Gyara R.T.Inventors: Andras Szego, Laszlo Pap, Lajos Nagy, Eva Somfai, Gyorgy Szucsany, Istvan Szekely, Aniko D. nee Molnar, Agnes Hegedus
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Patent number: 5153349Abstract: The invention relates to a process for the preparation of such isomer mixtures of cypermethrine of the Formula (I) ##STR1## wherein carbon atoms indicated by 1, 3 and .alpha. stand for a chiral carbon atom and the wavy line indicates cis or trans configuration related to the cyclopropane ring--which contains out of the theoretically possible 8-isomers of cypermethrine at least 95% of 1RtransS and 1StransR (Ib) isomer pair or only a mixture of 1RcisC and 1ScisR (Ia) and the isomer pair (Ib) of the ratio (Ia):(Ib)=55:45-25:75 by asymmetric transformation of second order performed in the presence of an amine base and solvent from a starting cypermethrine isomer mixture which contains next to the isomer pair (Ib) cis and other trans isomers or the isomer pair Ia+Ib at an undesired ratio.Type: GrantFiled: October 19, 1990Date of Patent: October 6, 1992Assignee: Chinoin Gyogyszer- es Vegyeszeti Termekek Gyara Rt.Inventors: Sandor Zoltan, Gyorgy Hidasi, Bela Bertok, Istavan Szekely, Janis Hajimichael, Sandor Botar, Lajos Nagy, Eva Somfai, Istvan Lak, Andras Rapi, Antal Gajary, Agnes Hegedus, Maria Tary
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Patent number: 5110976Abstract: A process is disclosed for preparing a synergistic, crystalline product consisting of solely enantiomer pair 1RCisS and 1SCisR and enantiomer pair 1RTransS and 1STransR of cypermethrin in a 3:7 to 5:5 crystalline mixture, which comprises the steps of: (a) epimerizing an oily melt or a saturated solution of enantiomer pair 1RCisS and 1SCisR and enantiomer pair 1RTransS and 1STransR in a ratio other than 3:7 to 5:5, or a mixture of enantiomer pair 1RCisS and 1SCisR, enantiomer pair 1RTransS and 1STransR together with enantiomer pair 1RCisR and 1SCisS and enantiomer pair 1RTransR and 1STransS, said saturated solution including a protic or apolar, aprotic inert organic solvent by treating said oily melt or saturated solution with an organic or inorganic base at a temperature of -15.degree. C. to 30.degree. C.Type: GrantFiled: May 7, 1991Date of Patent: May 5, 1992Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.Inventors: Gyorgy Hidasi, Istvan Szekely, Bela Bertok, Sandor Zoltan, Lajos Nagy, Antal Gajari, Eva Somfai, Agnes Hegedus, Laszlo Pap, Rudolf Soos, Erzsebet Radvany, Sandor Botar, Tamas Szabolcsi
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Patent number: 5075338Abstract: A method of treating a learning deficiency is disclosed wherein a patient in need of stimulating learning ability is treated with a therapeutically effective amount of a compound of the Formula (I) ##STR1## wherein R.sup.1 is C.sub.1 to C.sub.8 straight or branched chain alkyl, C.sub.7 to C.sub.10 phenylalkyl, phenyl, or C.sub.3 to C.sub.8 cycloalkyl; andR.sup.2 is C.sub.1 to C.sub.8 straight or branched chain alkyl, unsubstituted or substituted by halogen, hydroxy, C.sub.1 to C.sub.4 alkoxy or by 1 or 2 phenyl groups; or is C.sub.3 to C.sub.8 cycloalkyl;with the proviso that R.sup.1 and R.sup.2 together contain at least 3 carbon atoms; or a pharmaceutically acceptable salt thereof.Type: GrantFiled: October 11, 1989Date of Patent: December 24, 1991Assignee: Chinoin Gyogyszer- es Vergyeszeti Termekek Gyara Rt.Inventors: Jozsef Knoll, Antal Simay, Eva Szinnyei, Eva Somfai, Zoltan Torok, Karoly Mozsolits, Janos Bergmann
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Patent number: 5043163Abstract: The present invention relates to a multi-component pesticidal composition against anthropoda containing as active ingredient pyrethroides and phosphate esters and optionally piperonyl butoxide and excipients comprising as pyrethroid component 0.1 to 40 percent by weight of cypermethrin related to the total weight comprising out of the 8 possible isomers 40 to 100 percent by weight of 1RcisS and/or 1RtransS stereoisomer and as a second component at least one phosphoric acid, thiophosphoric acid or dithiophosphate being toxic on arthropoda at a ratio of 1:1-99 related to the amount of cypermethrin.Type: GrantFiled: August 9, 1990Date of Patent: August 27, 1991Assignee: Chinoin Gyogyszer- es Vegyeszeti Termekek Gyara Rt.Inventors: Laszlo Pap, Eva Somfai, Andras Szego, Istvan Szekely, Lajos Nagy, Gyorgy Hidasi, Sandor Zoltan, Andrea Toth, Bela Bertok, Sandor Botar, Antal Gajary, Agnes Hegedus, Aniko Deak
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Patent number: 5023337Abstract: The present invention is directed to the preparation of benzimidazole derivatives of the formula (I), ##STR1## wherein A=stands for S, SO or SO.sub.2,R.sup.1 =stands for C.sub.1-4 alkyl group,R.sup.2 =stands for C.sub.1-4 alkyl, C.sub.3-7 cycloalkyl or C.sub.6-10 aryl or aralkyl,comprising reacting a sulphochloride of the formula (II) ##STR2## with an alkyl aluminum compound of the formula (III).R.sub.n.sup.2 AlClhd (3-n) (III)The reaction is performed in one step.Type: GrantFiled: January 19, 1990Date of Patent: June 11, 1991Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.Inventors: Ferenc Sperber, Csaba Huszar, Attila Nemeth, Eva Somfai, Iren Pali nee Ivanics
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Patent number: 5013754Abstract: According to the present invention there is provided a synergistic insecticidal composition containing more than one active ingredients and being harmless to environment characterized by comprising in an amount of from 0.001 to 99% by weight a synthetic pyrethroid of the Formula /I/ ##STR1## namely substantially only the 1RtransS and 1StransR entantiomer-pair /Ib/ out from the possible eight isomers--optionally in admixture with an amount of up to 100% by weight of one or more activator/s/ and auxiliary agent/s/, particularly antioxidants, stabilizing agents, wetting agents, emulsifying agents, dispersing agents, antifoam agents, diluents and/or fillers.The enantiomer-pair Ib consisting of the 1RtransS and 1StransR isomers is new and the invention also relates to the said new enantiomer-pair and a process for the preparation thereof.Type: GrantFiled: June 16, 1989Date of Patent: May 7, 1991Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.Inventors: Gyorgy Hidasi, Istvan Szekely, Bela Bertok, Sandor Zoltan, Lajos Nagy, Antal Gajari, Eva Somfai, Agnes Hegedus, Laszlo Pap, Rudolf Soos, Erzsebet Radvany, Sandor Botar, Tamas Szabolcsi
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Patent number: 5008292Abstract: The invention relates to N-[2-(4-fluorophenyl)-1-methyl]-ethyl-N-methyl-N-propynyl amine of the Formula I ##STR1## and isomers and salts thereof. The compound of the Formula I is useful as an insecticide.Type: GrantFiled: November 25, 1987Date of Patent: April 16, 1991Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.Inventors: Zoltan Ecsery, Jozsef Knoll, Eva Somfai, Zoltan Torok, Eva Szinnyei, Karoly Mozsolits
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Patent number: 4963584Abstract: According to the present invention there is provided an insecticidal composition containing more than one active ingredients which comprises as active ingredient in an amount of 0.001-99% by weight a synthetic pyrethroid of the general Formula I ##STR1## wherein X stands for chlorine or bromine--namely out of the eight possible isomers at least 95% of a 55:45-25:75 mixture of the enantiomer-pairs Ia:Ib, wherein Ia is 1RcisS+1ScisR and Ib is 1RtransS++1StransR--if desired, in admixture with an activator and/or with an amount of up to 100% of an auxiliary agent, preferably an antioxidant, stabilizer, wetting agent, emulsifying agent, dispersing agent, antifoam agent, diluent, carrier, and/or filler.The advantage of the insecticidal composition of the present invention is that it is less toxical towards warm-blooded animals and useful parasites and is therefore much less harmful to the environment.Type: GrantFiled: June 19, 1989Date of Patent: October 16, 1990Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.Inventors: Gyorgy Hidasi, Istvan Szekely, Bela Bertok, Sandor Zoltan, Lajos Nagy, Antal Gajari, Eva Somfai, Agnes Hegedus, Laszlo Pap, Ruldof Soos, Erzsebet Radvany, Sandor Botar, Tamas Szabolcsi
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Patent number: 4960797Abstract: The invention relates to the new N-[2-/4-fluorophenyl/-1-methyl]-ethyl-N-methyl-N-propynyl amine of the Formula I ##STR1## and isomers and salts thereof. The compound of the formula I is useful as a selective MAO inhibitor.Type: GrantFiled: February 15, 1989Date of Patent: October 2, 1990Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.Inventors: Zoltan Ecsery, deceased, Jozsef Knoll, Eva Somfai, Zoltan Torok, Eva Szinnyei, Karoly Mozsolics
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Patent number: 4950682Abstract: The present invention relates to synergistic arthropodicidal composition of several pyrethroidal active ingredients causing no damage to warm-blooded organisms comprising pyrethroides and piperonyl butoxide as active ingredient which comprises as pyrethroidal active ingredient 0.1-20% by weight of 1StransR-alpha-cyano-3-phenoxy-benzyl-3- (2,2-dichlorvinyl)-2,2-dimethyl/cyclopropane-cyrboxylate of the Formula I ##STR1## 0.05-10% by weight of cis-trans-tetramethrin (3,4,5,6-tetrahydrophthalimido-methyl(1RS)-cis-trans-chrysantemate) or trans-tetramethrin of the Formula II ##STR2## and a further pyrethroide, 0.Type: GrantFiled: February 6, 1989Date of Patent: August 21, 1990Assignee: Chinoin Gyogyszer- es Vegyeszeti Termekek Gyara Rt.Inventors: Laszlo Pap, Peter Sarkozi, Eva Somfai, Andras Szego, Istvan Szekely, Gyorgy Hidasi, Sandor Zoltan, Aniko Deak nee Moinar, Agnes Hegedus, Bela Bertok, Sandor Botar, Antal Gajary, Lajos Nagy
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Patent number: 4925878Abstract: The compounds of the Formula I ##STR1## (wherein R is hydrogen or halogen) and pharmaceutically acceptable acid addition salts thereof are suitable for the prophylaxis of undesired and unfavorable symptoms (e.g. perspiration, nausea, vomiting, dizziness, etc.) which occur when healthy humans or mammal animals are subjected to unusual moving (e.g. during transportation on aeroplane, or vehicles, ships, etc.Type: GrantFiled: August 17, 1988Date of Patent: May 15, 1990Assignee: Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt.Inventors: Gyorgy Bodo, Jozsef Knoll, Eva Somfai, Sandor Virag, Ferenc Zak