Patents by Inventor Eva Trofast

Eva Trofast has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170165248
    Abstract: A solid, rapidly gelling oral pharmaceutical dosage form, as well as an aqueous formulation prepared thereof, comprising a) an acid sensitive proton pump inhibitor as active ingredient distributed in a multitude of enteric coated pellets, and b) a suspension modifying granulate. Furthermore, the invention relates to an improved process for the manufacture and the use of such formulation in medical treatment, including prevention of gastrointestinal disorders in humans.
    Type: Application
    Filed: February 10, 2017
    Publication date: June 15, 2017
    Applicant: AstraZeneca AB
    Inventors: Eva PERSSON, Eva TROFAST
  • Publication number: 20150079186
    Abstract: A solid, rapidly gelling oral pharmaceutical dosage form, as well as an aqueous formulation prepared thereof, comprising a) an acid sensitive proton pump inhibitor as active ingredient distributed in a multitude of enteric coated pellets, and b) a suspension modifying granulate. Furthermore, the invention relates to an improved process for the manufacture and the use of such formulation in medical treatment, including prevention of gastrointestinal disorders in humans.
    Type: Application
    Filed: December 3, 2014
    Publication date: March 19, 2015
    Inventors: Eva PERSSON, Eva TROFAST
  • Publication number: 20130273168
    Abstract: A solid, rapidly gelling oral pharmaceutical dosage form, as well as an aqueous formulation prepared thereof, comprising a) an acid sensitive proton pump inhibitor as active ingredient distributed in a multitude of enteric coated pellets, and b) a suspension modifying granulate. Furthermore, the invention relates to an improved process for the manufacture and the use of such formulation in medical treatment, including prevention of gastrointestinal disorders in humans.
    Type: Application
    Filed: June 5, 2013
    Publication date: October 17, 2013
    Inventors: Eva PERSSON, Eva TROFAST
  • Patent number: 8205611
    Abstract: A processing method and apparatus are disclosed for processing an inhaler component of a dry powder inhaler so as to remove any electrostatic charge and improve inhaler performance in drug delivery to the respiratory tract. The method includes exposing the inhaler component, while it contains an amount of medicament, to a gas in a chamber at a first predetermined pressure; exposing the inhaler component, in the chamber, to gas at a second pressure greater than the first pressure; and repeating the exposure of the inhaler component to gas at a pressure no greater than the first predetermined pressure.
    Type: Grant
    Filed: September 7, 2010
    Date of Patent: June 26, 2012
    Assignee: AstraZeneca AB
    Inventors: Magnus Olsson, Eva Trofast
  • Publication number: 20110056089
    Abstract: A processing method and apparatus are disclosed for processing an inhaler component of a dry powder inhaler so as to remove any electrostatic charge and improve inhaler performance in drug delivery to the respiratory tract. The method includes exposing the inhaler component, while it contains an amount of medicament, to a gas in a chamber at a first predetermined pressure; exposing the inhaler component, in the chamber, to gas at a second pressure greater than the first pressure; and repeating the exposure of the inhaler component to gas at a pressure no greater than the first predetermined pressure.
    Type: Application
    Filed: September 7, 2010
    Publication date: March 10, 2011
    Inventors: MAGNUS OLSSON, Eva Trofast
  • Patent number: 7896005
    Abstract: The invention relates to a processing method and apparatus, more particularly, to processing a body so as to remove any electrostatic charge and improve inhaler performance in drug delivery to the respiratory tract.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: March 1, 2011
    Assignee: AstraZeneca AB
    Inventors: Magnus Olsson, Eva Trofast
  • Publication number: 20100183729
    Abstract: The invention relates to a stable pharmaceutical composition useful in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD) and a novel micronisation process for manufacturing a stable formulation for formoterol or its enantiomers and a carrier/diluent comprising a carbohydrate such as lactose.
    Type: Application
    Filed: January 14, 2010
    Publication date: July 22, 2010
    Applicant: AstraZeneca AB
    Inventor: Eva Trofast
  • Patent number: 7670625
    Abstract: The invention relates to a stable pharmaceutical composition useful in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD) and a novel micronisation process for manufacturing a stable formulation for formoterol or its enantiomers and a carrier/diluent comprising a carbohydrate such as lactose.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: March 2, 2010
    Assignee: AstraZeneca AB
    Inventor: Eva Trofast
  • Patent number: 7354913
    Abstract: Inhalable pharmaceutical compositions are provided, for use in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD). These compositions have high storage stability, and include formoterol and a corticosteroid.
    Type: Grant
    Filed: February 8, 2005
    Date of Patent: April 8, 2008
    Assignee: AstraZeneca AB
    Inventors: Eva Trofast, Karin Malmqvist-Granlund, Per-Gunnar Nilsson, Kyrre Thalberg
  • Publication number: 20080020053
    Abstract: A solid rapidly gelling oral pharmaceutical dosage form, as well as aqueous suspensions prepared thereof, comprising an acid sensitive proton pump inhibitor as active ingredient distributed in a multitude of enteric coated pellets and a suspension modifying granulate comprising a rapidly dissolving diluent granulated together with a gelling agent chosen among xanthan gums, and an acidic pH-regulating agent and a binder. The suspension modifying granulate is rapidly disintegrating and gelling when suspended in an aqueous medium and thus forming a homogenous stable and robust suspension having a reproducible and stable viscosity. Furthermore the invention relates to an improved process for its manufacture and the use of such formulation in medical treatment including prevention of gastrointestinal disorders in humans.
    Type: Application
    Filed: December 20, 2005
    Publication date: January 24, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Eva Persson, Eva Trofast
  • Publication number: 20070259048
    Abstract: The invention relates to a stable pharmaceutical composition useful in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD) and a novel micronisation process for manufacturing a stable formulation for formoteral or its enantiomers and a carrier/diluent comprising a carbohydrate such as lactose.
    Type: Application
    Filed: January 25, 2007
    Publication date: November 8, 2007
    Inventor: Eva Trofast
  • Publication number: 20070107721
    Abstract: The invention relates to a processing method and apparatus, more particularly, to processing a body so as to remove any electrostatic charge and improve inhaler performance in drug delivery to the respiratory tract.
    Type: Application
    Filed: October 4, 2004
    Publication date: May 17, 2007
    Applicant: ASTRAZENECA AB
    Inventors: Magnus Olsson, Eva Trofast
  • Patent number: 7179489
    Abstract: The invention relates to a stable pharmaceutical composition useful in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD) and a novel micronization process for manufacturing a stable formulation for formoterol or its enantiomers and a carrier/diluent comprising a carbohydrate such as lactose.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: February 20, 2007
    Assignee: AstraZeneca AB
    Inventor: Eva Trofast
  • Publication number: 20060134210
    Abstract: A solid, rapidly gelling oral pharmaceutical dosage form, as well as an aqueous formulation prepared thereof, comprising a) an acid sensitive proton pump inhibitor as active ingredient distributed in a multitude of enteric coated pellets, and b) a suspension modifying granulate. Furthermore, the invention relates to an improved process for the manufacture and the use of such formulation in medical treatment, including prevention of gastrointestinal disorders in humans.
    Type: Application
    Filed: December 19, 2005
    Publication date: June 22, 2006
    Inventors: Eva Persson, Eva Trofast
  • Publication number: 20050207989
    Abstract: Inhalable pharmaceutical compositions are provided, for use in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD). These compositions have high storage stability, and include formoterol and a corticosteroid.
    Type: Application
    Filed: February 8, 2005
    Publication date: September 22, 2005
    Applicant: AstraZeneca AB
    Inventors: Eva Trofast, Karin Malmqvist-Granlund, Per-Gunnar Nilsson, Kyrre Thalberg
  • Publication number: 20050152847
    Abstract: The present invention relates to specific excipients for powder formulations for oral and nasal inhalation.
    Type: Application
    Filed: March 3, 2003
    Publication date: July 14, 2005
    Inventors: Eva Trofast, Jan Trofast
  • Patent number: 6869942
    Abstract: Inhalable pharmaceutical compositions are provided, for use in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD). These compositions have high storage stability, and include formoterol and a corticosteroid.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: March 22, 2005
    Assignee: AstraZeneca AB
    Inventors: Eva Trofast, Karin Malmqvist-Granlund, Per-Gunnar Nilsson, Kyrre Thalberg
  • Publication number: 20030236238
    Abstract: The invention relates to novel pharmaceutical compositions useful in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD).
    Type: Application
    Filed: November 15, 2002
    Publication date: December 25, 2003
    Inventors: Eva Trofast, Karin Malmqvist-Granlund, Per-Gunnar Nilsson, Kyrre Thalberg
  • Publication number: 20030129245
    Abstract: The invention relates to a stable pharmaceutical composition useful in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD) and a novel micronisation process for manufacturing a stable formulation for formoterol or its enantiomers and a carrier/diluent comprising a carbohydrate such as lactose.
    Type: Application
    Filed: November 18, 2002
    Publication date: July 10, 2003
    Inventor: Eva Trofast
  • Patent number: 6391340
    Abstract: There is described a solid particulate pharmaceutical formulation suitable for application to the nose comprising finely divided additive particles and finely divided drug particles, wherein the mass median diameter of the drug particles is greater than that of the additive particles.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: May 21, 2002
    Assignee: AstraZeneca AB
    Inventors: Karin Malmqvist-Granlund, Gordon Santesson, Eva Trofast