Abstract: An aeroponic grow tower is provided. The tower includes a modular wall system located between a cover and a base. The wall system includes a plurality of individual flat, four-sided wall panels. The identical wall panels are removably connected along their side edges into one or more levels having a polygonal shape. Levels are aligned and stack atop the base and each other. The wall panels have openings defining grow sites configured to support plants such that foliage extends to the outside and roots hang inside the tower. A pump delivers nutrient solution from the base to a high-rotational speed spray nozzle which aerosolizes the solution. The spray also impacts the interior surface further aerosolizing the solution. Channels direct solution running down the interior surface to the grow sites which include secondary reservoirs to provide a further source of nutrient solution in extreme temperatures and reduce power usage. A ventilation system and seedling covers are also provided.

Abstract: An aeroponic grow tower is provided. The tower includes a modular wall system located between a cover and a base. The wall system includes a plurality of individual flat, four-sided wall panels. The identical wall panels are removably connected along their side edges into one or more levels having a polygonal shape. Levels are aligned and stack atop the base and each other. The wall panels have openings defining grow sites configured to support plants such that foliage extends to the outside and roots hang inside the tower. A pump delivers nutrient solution from the base to a high-rotational speed spray nozzle which aerosolizes the solution. The spray also impacts the interior surface further aerosolizing the solution. Channels direct the solution running down the interior surface to the grow sites which include secondary reservoirs to provide a further source of nutrient solution. A ventilation system and seedling covers are also provided.

Abstract: An aeroponic grow tower is provided. The tower includes a modular wall system located between a cover and a base. The wall system is comprised of a plurality of individual flat, four-sided wall panels. The identical wall panels are removably connected along their side edges via a click-lock, semi-spherical, elongated ball joint into one or more levels having a polygonal shape. Levels are aligned and stack atop the base and each other via half-lap joints at the top and bottom sides forming a flush interior surface. The wall panels have openings defining grow sites configured to support substrate and plants such that foliage extends to the outside and roots hang inside the tower. A pump delivers nutrient solution from the base up to a high-rotational speed spray nozzle which aerosolizes the nutrient solution which gently rains down upon the roots. The spray also impacts the interior surface further aerosolizing the solution.

Abstract: Methods and compositions are provided for transgene expression in target cells. Expression constructs using an inducible amplification system to drive expression of a therapeutic gene or other gene of interest in mammalian host cells are provided, as well as methods therefor. Inducible expression of the transgenes at high levels under physiologic conditions results from induction by hyperthermic conditions relative to the basal temperature of the host cells.

Abstract: Compositions and methods for treating multiple sclerosis are disclosed herein. Embodiments of the present invention include methods of treating a multiple sclerosis patient via the administration of a therapeutically effective amount of a composition comprising a compound of the formula: wherein, R1 is heteroalkyl, heterocycloalkyl, or heteroaryl; R2, R4 and R6 are independently hydrogen, halogen, nitro, amino, hydroxy, C1-C6 alkyl, C1-C6 heteroalkyl, heterocycloalkyl or aryl; R3, R5, and R7 are independently hydrogen or C1-C6 alkyl, or R3 and R4 taken together with the carbon atoms to which they are attached form a phenyl ring, or R4 and R5 taken together with the carbon atoms to which they are attached form a phenyl ring, or R5 and R7 taken together with the carbon atoms to which they are attached form a phenyl ring; and n1 and n2 are independently 0, 1 or 2; or a pharmaceutically acceptable salt, a prodrug, or a mixture thereof.

Abstract: Methods of treating imexon-induced constipation in patients in conjunction with their participation in a cancer treatment regimen are disclosed herein. Embodiments of the invention include the treatment of imexon-induced constipation arising from the administration of imexon alone or in combination with other chemotherapeutic agents. Also disclosed are pharmaceutical compositions and pharmaceutical kits comprising a therapeutically effective amount of imexon and an amount of a laxative effective in treating imexon-induced constipation. Embodiments of the present invention include prophylactic anticonstipation regimens comprising one or more laxatives that may be prescribed and/or administered prior to or during the course of treatment of the patient with imexon.

Abstract: Expression constructs using an inducible amplification system to drive expression of a therapeutic gene or other genes of interest in mammalian cells are provided, as well as methods of using the same.

Abstract: The present invention relates to inducible gene expression constructs and methods of inducing gene expression using a combination of inducing agents.

Abstract: Methods and compositions are provided for transgene expression in target cells. Expression constructs using an inducible amplification system to drive expression of a therapeutic gene or other gene of interest in mammalian host cells are provided, as well as methods therefor. Inducible expression of the transgenes at high levels under physiologic conditions results from induction by hyperthermic conditions relative to the basal temperature of the host cells.

Abstract: The present invention provides compositions useful in treating cancer. The compositions include a synergistic combination of an antineoplastic thiol-binding mitochondrial oxidant with an antineoplastic nucleic acid binding agent, an antineoplastic antimetabolite base analog, or docetaxel. Also provided are methods of assaying the synergistic effects of the combinations and methods of treating cancer using the synergistic combinations.

Abstract: Expression constructs using an inducible amplification system to drive expression of a therapeutic gene or other genes of interest in mammalian cells are provided, as well as methods of using the same.

Abstract: Methods and compositions are provided for transgene expression in target cells. Expression constructs using an inducible amplification system to drive expression of a therapeutic gene or other gene of interest in mammalian host cells are provided, as well as methods therefor. Inducible expression of the transgenes at high levels under physiologic conditions results from induction by hyperthermic conditions relative to the basal temperature of the host cells.

Abstract: The present invention relates to inducible gene expression constructs and methods of inducing gene expression using a combination of inducing agents.

Abstract: Disclosed are novel compositions comprising a lipid and imexon or a derivative thereof. Also disclosed are liposomal compositions comprising imexon or a derivative thereof. Methods for administrating pharmaceutically acceptable compositions comprising a lipid and imexon or a derivative thereof for the treatment of diseases, such as cancer, are also disclosed herein.

Abstract: Human monoclonal antibodies which belong to the IgGl subclass and are specific for HIV are described. The monoclonal antibodies have potential for use in the diagnosis, prevention and therapy of HIV infection.

Abstract: Human monoclonal antibodies which belong to the IgG1 subclass and are specific for HIV are described. The monoclonal antibodies have potential for use in the diagnosis, prevention and therapy of HIV infection.