Abstract: A device for preventing accidental needle puncture injuries comprises a sleeve for attachment to a needle or a needle and syringe assembly prior to use. The sleeve has a relaxed condition in which the needle is passed through an eccentrically positioned opening in a top member and exposed for use. The needle hub and/or syringe is firmly anchored by a base member. The top and base members are interconnected by living hinges to a pair of opposedly inverted sidewalls each comprising two members of unequal length interconnected by sidewall living hinges which are open when the device is in a relaxed condition. After needle use, the sidewalls are manually biased toward each other by the user, thereby closing the sidewall hinges, and the device assumes an extended condition. The needle is thereby extracted from the top member opening and the needle tip is engaged by top member needle tip engaging configuration. Elements are also provided for trapping the needle in the device after use.