Abstract: The present invention features a simplified sample processing method (e.g., VELOX) to collect high amounts of nucleic acids (e.g., genomic DNA (gDNA)) without equipment and without protein or other contaminants to interfere with sensor signals or similar nucleic acid detection test (sensors or per reagents). Specifically, the present invention provides systems, devices, and methods that allow for isolation and extraction of nucleic acids (e.g., gDNA) especially in a point of need setting.

Abstract: The present invention relates to electrochemical sensors for oligonucleotide detection. The sensors may feature a probe composition, e.g., an oligonucleotide and an indicator attached to a 5? end of the probe, attached to a surface such as gold; and a back-filler additive bound to at least a portion space on the surface of the electrochemical sensor not occupied by the probe composition.

Abstract: The present invention features methods for manufacturing an electrochemical sensor for detecting a diagnostic target oligonucleotide. The methods described herein provide for an electrochemical sensor with a higher level of coverage of the probes on its surface, thus allowing for more sensitive detection of a target oligonucleotide. The methods may feature first mixing disulfide terminated oligonucleotides having a free thiol moiety at the 3? end with a gold substrate and subsequently introducing to the gold substrate a composition for reducing thiol moieties to cause the oligonucleotides to bind to the surface of the gold substrate. In some embodiments, the method comprises removing excess thiol and oligonucleotides, which may help with non-competitive binding. In some embodiments, the method comprises rinsing the gold substrate with water and drying with nitrogen.

Abstract: A system can facilitate pre-treatment a biofluid sample for various applications for monitoring and/or tracking a subject's health. The system includes a sample collection component that can collect the biofluid sample. The system also includes a mixing component that includes a media with a material. Upon adding the biofluid sample to the mixing component, the biofluid sample mixes with the media. The system also includes a filter component that can filter the media from the biofluid sample. After the media is filtered from the biofluid sample, the biofluid sample can be provided to an analyte analysis application.

Abstract: A system can facilitate pre-treatment a biofluid sample for various applications for monitoring and/or tracking a subject's health. The system includes a sample collection component that can collect the biofluid sample. The system also includes a mixing component that includes a media with a material. Upon adding the biofluid sample to the mixing component, the biofluid sample mixes with the media. The system also includes a filter component that can filter the media from the biofluid sample. After the media is filtered from the biofluid sample, the biofluid sample can be provided to an analyte analysis application.

Abstract: A system can facilitate pre-treatment a biofluid sample for various applications for monitoring and/or tracking a subject's health. The system includes a sample collection component that can collect the biofluid sample. The system also includes a mixing component that includes a media with a material. Upon adding the biofluid sample to the mixing component, the biofluid sample mixes with the media. The system also includes a filter component that can filter the media from the biofluid sample. After the media is filtered from the biofluid sample, the biofluid sample can be provided to an analyte analysis application.

Abstract: A system can facilitate detection of 1, 5-anhydroglucitol (1, 5-AG) present in a saliva sample. The saliva sample can be placed in contact with a portion of a sensing device that includes a 1, 5-AG sensor. An indicator of a concentration of 1, 5-AG in the saliva sample can be detected by the 1, 5-AG sensor. The 1, 5-AG sensor can send the indicator to a computing device that includes a processing unit. The processing unit can execute instructions stored in non-transitory memory to receive the indicator; measure an amount of 1, 5-AG in the saliva sample based on the indicator; and provide an output related to the amount of 1, 5-AG in saliva sample. The amount of 1, 5-AG in the saliva sample can be used as a diagnostic property for a subject who produced the saliva sample.

Abstract: A system can facilitate detection of the presence of an analyte or a contaminant in a contaminated sample. The system includes a first sensor to detect the analyte and a contaminant in the sample and a second sensor to detect the analyte or the contaminant in the sample. The detections are compared by a device comprising a processor to eliminate either the analyte or the contaminant from the final detected result.

Abstract: A system can facilitate detection of the presence of an analyte or a contaminant in a contaminated sample. The system includes a first sensor to detect the analyte and a contaminant in the sample and a second sensor to detect the analyte or the contaminant in the sample. The detections are compared by a device comprising a processor to eliminate either the analyte or the contaminant from the final detected result.

Abstract: Structurally stable and mechanically strong ceramic oxide aerogels are provided. The aerogels are cross-linked via organic polymer chains that are attached to and extend from surface-bound functional groups provided or present over the internal surfaces of a mesoporous ceramic oxide particle network via appropriate chemical reactions. The functional groups can be hydroxyl groups, which are native to ceramic oxides, or they can be non-hydroxyl functional groups that can be decorated over the internal surfaces of the ceramic oxide network. Methods of preparing such mechanically strong ceramic oxide aerogels also are provided.

Abstract: The invention is directed, in an embodiment, to an inherently conductive polymer comprising a conductive polymer, carbon nanotubes, and dinonylnaphthalene sulfonic acid. The conductive polymer may comprise polyaniline. The invention is also directed to polymeric films and supercapacitors comprising the inherently conductive polymer.

Abstract: Structurally stable and mechanically strong ceramic oxide aerogels are provided. The aerogels are cross-linked via organic polymer chains that are attached to and extend from surface-bound functional groups provided or present over the internal surfaces of a mesoporous ceramic oxide particle network via appropriate chemical reactions. The functional groups can be hydroxyl groups, which are native to ceramic oxides, or they can be non-hydroxyl functional groups that can be decorated over the internal surfaces of the ceramic oxide network. Methods of preparing such mechanically strong ceramic oxide aerogels also are provided.

Abstract: Structurally stable and mechanically strong ceramic oxide aerogels are provided. The aerogels are cross-linked via organic polymer chains that are attached to and extend from surface-bound functional groups provided or present over the internal surfaces of a mesoporous ceramic oxide particle network via appropriate chemical reactions. The functional groups can be hydroxyl groups, which are native to ceramic oxides, or they can be non-hydroxyl functional groups that can be decorated over the internal surfaces of the ceramic oxide network. Methods of preparing such mechanically strong ceramic oxide aerogels also are provided.

Abstract: A method and apparatus for increasing detection characteristics of a chemical sensor array that has been previously exposed to an agent in order to detect and categorize the agent. Ultraviolet light at a predetermined wavelength is applied to the chemical sensor array, in order to desorb the agent from the chemical sensor array, so as to increase a resistance of the chemical sensor array. Alternatively or together with the ultraviolet light, a bias voltage is applied to at least one biasing electrode making up the chemical sensor array, in order to desorb the agent from the chemical sensor array, so as to increase the resistance of the chemical sensor array. The chemical sensor array may be a carbon nanotube sensor array.