Patents by Inventor Everett Greenberg

Everett Greenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Autoinducer molecule
    Publication number: 20050250841
    Abstract: Autoinducer molecules, e.g., N-(3-oxododecanoyl)homoserine lactone, for Pseudomonas aeruginosa are described. The molecules regulate gene expression in the bacterium. Therapeutic compositions and therapeutic methods involving analogs and/or inhibitors of the autoinducer molecules also are described. The molecules are useful for treating or preventing infection by Pseudomonas aeruginosa.
    Type: Application
    Filed: January 5, 2005
    Publication date: November 10, 2005
    Inventors: James Pearson, Kendall Gray, Luciano Passador, Kenneth Tucker, Anatol Eberhard, Barbara Iglewski, Everett Greenberg
  • Methods of inhibiting and treating bacterial biofilms by metal chelators
    Publication number: 20050143286
    Abstract: The invention presented herein provides methods and compositions for the prevention and treatment of bacterial infections. The methods are based on the discovery that depletion of bioavailable iron stimulates surface motility in bacteria thus inhibiting the ability of a bacterial population to develop into a biofilm.
    Type: Application
    Filed: October 4, 2004
    Publication date: June 30, 2005
    Applicant: THE UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Pradeep Singh, Michael Welsh, Everett Greenberg
  • Novel autoinducer molecules and uses therefor
    Publication number: 20050009869
    Abstract: Novel bacterial quinolone signal molecules and, more particularly, pseudomonas quinolone signal (“PQS”) molecules, e.g., 2-heptyl-3-hydroxy-4-quinolone, and analogs and derivatives thereof are described. Therapeutic compositions containing the molecules, and therapeutic methods, methods of for regulating gene expression, methods for identifying modulators of the autoinducer molecules, and methods of modulating quorum sensing signalling in bacteria using the compounds of the invention are also described.
    Type: Application
    Filed: September 16, 2004
    Publication date: January 13, 2005
    Inventors: Everett Pesci, Barbara Iglewski, Jared Milbank, James Pearson, Andrew Kende, Everett Greenberg