Abstract: The utilization of biomarkers, which include objectively measureable and assessable indicators of a biological process or biological state, in treatments is disclosed. Particularly, biomarkers enabling optimisation of treatment regimes and the use of the biomarkers in tests for the prediction of optimised treatments and treatment outcomes in the treatment of Major Depressive Disorder (MDD) are disclosed. Measurable and assessable cognitive and/or genomic parameters can be biomarkers indicating changes in system severity of MDD.

Abstract: The present invention relates to the field of biomarkers and in particular to their utilisation in treatment. Embodiments of the invention have been particularly developed as biomarkers enabling optimisation of treatment regimes and as uses of the biomarkers in tests for the prediction of optimised treatments and treatment outcomes in the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents. The invention will be described hereinafter with reference to this application. However, it will be appreciated that the invention is not limited to this particular field of use.

Abstract: The present invention relates to the field of biomarkers and in particular to their utilisation in treatment. Embodiments of the invention have been particularly developed as biomarkers enabling optimisation of treatment regimes and as uses of the biomarkers in tests for the prediction of optimised treatments and treatment outcomes in the treatment of Major Depressive Disorder (MDD).

Abstract: The utilization of biomarkers, which include objectively measurable and assessable indicators of a biological process or biological state, in treatments is disclosed. Particularly, biomarkers enabling optimisation of treatment regimes and the use of the biomarkers in tests for the prediction of optimised treatments and treatment outcomes in the treatment of Major Depressive Disorder (MDD) are disclosed. Measurable and assessable cognitive and/or genomic parameters can be biomarkers indicating changes in system severity of MDD.

Abstract: A method of determining the conductance of the skin of a human or animal, the method including the step of: (a) eliminating any equivalent parasitic voltages in the skin by taking multiple different measurements of the conductance utilizing different probe voltage levels, (b) calculating the conductance from the sampled results of the multiple different measurements.

Abstract: A sensor device for transcutaneous monitoring a blood flow within a human or animal, the sensor device including: a microphone for picking up pneumo-acoustic changes; and a diaphragm interposed between the microphone and the surface of a user when in use, forming a sealed cavity between the microphone and diaphragm surface.

Abstract: A method is disclosed for rule based healthcare for use in the treatment of a patient. The method includes (a) providing a storage means for storing data indicative of a plurality of decision states, (b) presenting at least one query associated with a decision state, (c) receiving a corresponding at least one response to said at least one query, (d) comparing said response to a plurality of predefined responses ranges for selecting a new query associated with a new decision state, (e) transitioning to the new decision state, and (f) repeating steps (b) through (e) until a terminating decision state is reached.

Abstract: The present invention is concerned with methods and compositions for simultaneously treating or modulating memory and mood within the same individual.

Abstract: A method of providing diagnosis capability, diagnosis of the effects of treatment or diagnosis of distinctive capabilities of a test subject, the method can comprise the steps of: (a) carrying out a series of tests on a group of subjects of at least two modal measures, the modal measures comprising brain-body function, brain structure, neuropsychological, personality, genetics, personal history, performance and behaviour; and (b) examining the inter-relationships between the modal measures to output an analysis of the inter-relationships of two or more measures of the tests results of the group of subjects.