Patents by Inventor Fabian Somers

Fabian Somers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilization of pharmaceutical protein formulations with small peptides
    Patent number: 7141544
    Abstract: The present invention relates to stable pharmaceutical protein formulations that are stabilized using peptide stabilizers selected from the group consisting of Gly-Gly, Gly-Gly-Gly, Gly-Tyr, Gly-Phe, Gly-His, Gly-Asp, Gly-Ala, Ala-Gly, Ala-Ala, derivatives thereof and mixtures thereof. Furthermore, the present invention relates to stable pharmaceutical formulations comprising erythropoietin and peptide stabilizers selected from dipeptides, tripeptides, tetrapeptides, pentapeptides, and mixtures thereof. In addition to peptide stabilizers, the formulations may contain surfactants.
    Type: Grant
    Filed: October 10, 2003
    Date of Patent: November 28, 2006
    Assignees: Baxter International, Inc., Baxter Healthcare S.A.
    Inventors: Fabian Somers, Dirk Faict
  • Stabilization of pharmaceutical protein formulations with small peptides
    Publication number: 20050080011
    Abstract: The present invention relates to stable pharmaceutical protein formulations that are stabilized using peptide stabilizers selected from the group consisting of Gly-Gly, Gly-Gly-Gly, Gly-Tyr, Gly-Phe, Gly-His, Gly-Asp, Gly-Ala, Ala-Gly, Ala-Ala, derivatives thereof and mixtures thereof. Furthermore, the present invention relates to stable pharmaceutical formulations comprising erythropoietin and peptide stabilizers selected from dipeptides, tripeptides, tetrapeptides, pentapeptides, and mixtures thereof. In addition to peptide stabilizers, the formulations may contain surfactants.
    Type: Application
    Filed: October 10, 2003
    Publication date: April 14, 2005
    Inventors: Fabian Somers, Dirk Faict
  • 1,2,4-benzothiadiazine derivatives, their preparation and use
    Patent number: 6242443
    Abstract: 1,2,4-Benzothiadiazine derivatives represented by formula wherein D, R1, R2, R3, R4, R5, R12, R13, R14, R15 are defined in the description, composition thereof and methods for preparing the compounds are described. The compounds are useful in the treatment of diseases of the central nervous system, the cardiovascular system, the pulmonary system, the gastrointestinal system and the endocrinological system.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: June 5, 2001
    Assignee: Novo Nordisk AIS
    Inventors: Bernard Pirotte, Philippe Lebrun, Pascal De Tullio, Fabian Somers, Jacques Delarge, John Bondo Hansen, Flemming Elmelund Nielsen, Holger Claus Hansen, John Patrick Mogensen, Tina Møller-Tagmose
  • Pyrido-1,2,4-thiadiazine and pyrido-1,4-thiazine derivatives, their preparation and use
    Patent number: 5792764
    Abstract: Pyrido-1,2,4-thiadiazine and pyrido-1,4-thiazine derivatives represented by the formula ##STR1## wherein A, B, D, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are defined in the description, compositions thereof and methods for preparing the compounds are described. The compounds are useful in the treatment of diseases of the central nervous system, the cardiovascular system, pulmonary system, the gastrointestinal system and the endocrinologic system.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: August 11, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Bernard Pirotte, Philippe Lebrun, Pascal De Tullio, Fabian Somers, Jacques Delarge, Holger Claus Hansen, Flemming Elmelund Nielsen, John Bondo Hansen