Abstract: A bioprinting system comprises: a) a printing module containing at least one printhead for printing transferable objects of biological interest and at least one target, b) a feed source for the printhead for printing objects of biological interest, c) an activation means for the transfer of the objects of biological interest to the target, d) a means for relative displacement of the printhead with respect to the target, e) a sterilizable sealed enclosure, characterized in that —the printing module is placed the sterilizable sealed enclosure —the activation means is located outside of the sterilizable sealed enclosure, —and the sterilizable sealed enclosure has a leaktight interaction zone with the activation means.

Abstract: A printing method employs a piece of equipment comprising an energy-delivering exciter that is orientable to produce a punctiform interaction with at least one ink that possibly contains non-uniformities and that is deposited on a printing medium including a transparent interaction area, in order to cause the transfer of a targeted portion of the ink to a receiver. The method includes a step of generating a wetting film at least partially covering the transparent interaction area, followed by a step of depositing the ink on the surface of the wetting film and transferring steps.

Abstract: A method for printing uses at least one bio-ink. The method also uses at least one laser print head to deposit at least one droplet of at least one bio-ink onto a depositing surface of a receiving substrate. The printing method uses at least one nozzle print head to deposit at least one droplet of at least one bio-ink onto a depositing surface of the same receiving substrate as the laser print head.

Abstract: A bio-printing process comprises a step of preparing a target digital model representative of the three-dimensional organization of the tissue to be produced, a step of controlling a bio-printing instrument for the deposition of a plurality of layers of living cells and of biomaterials, a step of calculation of a digital printing model as a function of the digital model of the product to be produced, and of a model predicting change, and also characteristics of the constituents to be printed. The step of controlling the bio-printing instrument is carried out according to the digital printing model calculated in this way. A system is also described for implementing this process.

Abstract: A printing method employs a piece of equipment comprising an energy-delivering exciter that is orientable to produce a punctiform interaction with at least one ink that possibly contains non-uniformities and that is deposited on a printing medium including a transparent interaction area, in order to cause the transfer of a targeted portion of the ink to a receiver. The method includes a step of generating a wetting film at least partially covering the transparent interaction area, followed by a step of depositing the ink on the surface of the wetting film and transferring steps.

Abstract: An apparatus for transferring bio-ink onto a target having a slide defining a receiving area of a film of fluid containing inhomogeneities, a laser source associated with controlled diversion means and an optical block for focusing in a plane of the fluid film in order to apply a local pulse, wherein the apparatus also comprises imaging means and means for analyzing images in order to recognize the geometric positions of the inhomogeneities in the film, and an observable feature of each of the inhomogeneities (size, shape factor, type of particles, age of the particle, density, type of biomaterial, molecule, etc.) recognized by the appropriate analysis means. The apparatus further comprises selection means for selecting at least one of the inhomogeneous areas, and means for controlling the diversion in order to direct the laser beam toward the position of the inhomogeneous area and trigger the firing of the laser.

Abstract: A bioprinting system comprises: a) a printing module containing at least one printhead for printing transferable objects of biological interest and at least one target, b) a feed source for the printhead for printing objects of biological interest, c) an activation means for the transfer of the objects of biological interest to the target, d) a means for relative displacement of the printhead with respect to the target, e) a sterilizable sealed enclosure, characterized in that—the printing module is placed the sterilizable sealed enclosure—the activation means is located outside of the sterilizable sealed enclosure,—said and the sterilizable sealed enclosure has a leaktight interaction zone with the activation means.

Abstract: A bioprinting system for manufacturing a structured biological material, from materials of which at least a portion is constituted by biological particles (cells and cell derivatives), comprises: a) a printing assembly containing at least one print head for printing objects of biological interest and at least one target, b) a supply source for supplying the print head with objects of biological interest, c) a means for bioprinting the objects of biological interest, and d) a means for moving the print head relative to the target, characterized in that the movement means is constituted by a robot controlling the movement of the target along six axes, at least one of the print heads being stationary during the printing phase.

Abstract: A method for printing uses at least one bio-ink. The method also uses at least one laser print head to deposit at least one droplet of at least one bio-ink onto a depositing surface of a receiving substrate. The printing method uses at least one nozzle print head to deposit at least one droplet of at least one bio-ink onto a depositing surface of the same receiving substrate as the laser print head.

Abstract: The present invention deals with a cellularized dressing and the method for production of such a dressing, where this method preferably comprises a step of bioprinting of cells.

Abstract: A method for printing uses at least one bio-ink. The method also uses at least one laser print head to deposit at least one droplet of at least one bio-ink onto a depositing surface of a receiving substrate. The printing method uses at least one nozzle print head to deposit at least one droplet of at least one bio-ink onto a depositing surface of the same receiving substrate as the laser print head.

Abstract: A device for deposition of particles on a target from a transparent slide having a film formed by a fluid containing suspended particles, by locally exciting the film using a laser, includes means for observing the local excitation region. The observation means comprise a sensor and a light source, the optical axes of which are substantially shared in a space between an optical splitter and the film. The optical beam of the imaging system and the optical beam of the laser are coaxially arranged in the space between the controlled optical deflection means and the film. The device comprises a first focusing optical unit arranged between the controlled optical deflection means and the film. The device comprises a second image-combining optical unit positioned between the sensor and the splitter, the sensor being positioned in the focal plane of the second optical unit.

Abstract: The present disclosure relates to equipment and a method for additive manufacturing, comprising an orientable energy excitation means for generating intermittent interaction with a fluid covering a blade in order to trigger a jet oriented in the direction of a target, the fluid consisting of a liquid vector containing inhomogeneities, wherein: the fluid forms a liquid film of a thickness measuring less than 500 ?m on a blade having at least one area allowing the interaction with the laser, into which at least one inlet leads, the interaction area leading into at least one outlet, the equipment also comprising means for the circulation of the fluid between the inlet and the outlet.

Abstract: A bio-printing process comprises a step of preparing a target digital model representative of the three-dimensional organization of the tissue to be produced, a step of controlling a bio-printing instrument for the deposition of a plurality of layers of living cells and of biomaterials, a step of calculation of a digital printing model as a function of the digital model of the product to be produced, and of a model predicting change, and also characteristics of the constituents to be printed. The step of controlling the bio-printing instrument is carried out according to the digital printing model calculated in this way. A system is also described for implementing this process.

Abstract: A device for deposition of particles on a target from a transparent slide having a film formed by a fluid containing suspended particles, by locally exciting the film using a laser, includes means for observing the local excitation region. The observation means comprise a sensor and a light source, the optical axes of which are substantially shared in a space between an optical splitter and that the film. The optical beam of the imaging system and the optical beam of the laser are coaxially arranged in the space between the controlled optical deflection means and the film. The device comprises a first focusing optical unit arranged between the controlled optical deflection means and the film. The device comprises a second image-combining optical unit positioned between the sensor and the splitter, the sensor being positioned in the focal plane of the second optical unit.

Abstract: An apparatus for transferring bio-ink onto a target having a slide defining a receiving area of a film of fluid containing inhomogeneities, a laser source associated with controlled diversion means and an optical block for focusing in a plane of the fluid film in order to apply a local pulse, wherein the apparatus also comprises imaging means and means for analyzing images in order to recognize the geometric positions of the inhomogeneities in the film, and an observable feature of each of the inhomogeneities (size, shape factor, type of particles, age of the particle, density, type of biomaterial, molecule, etc.) recognized by the appropriate analysis, means. The apparatus further comprises selection means for selecting at least one of the inhomogeneous areas, and means for controlling the diversion in order to direct the laser beam toward the position of the inhomogeneous area and trigger the firing of the laser.

Abstract: A method for printing uses at least one ink. The method includes: a step of focusing a laser beam so as to generate a cavity in an ink film; a step of forming at least one ink droplet from a free surface of the ink film; and a step of depositing the droplet onto a depositing surface of a receiving substrate positioned at a given distance from the film. The laser beam is oriented in the direction opposite the gravitational force. The free surface of the film is oriented upwards towards the depositing surface placed above the ink film.

Abstract: A method for printing uses at least one ink. The method includes: a step of focusing a laser beam so as to generate a cavity in an ink film; a step of forming at least one ink droplet from a free surface of the ink film; and a step of depositing the droplet onto a depositing surface of a receiving substrate positioned at a given distance from the film. The laser beam is oriented in the direction opposite the gravitational force. The free surface of the film is oriented upwards towards the depositing surface placed above the ink film.

Abstract: A method for printing uses at least one bio-ink. The method also uses at least one laser print head to deposit at least one droplet of at least one bio-ink onto a depositing surface of a receiving substrate. The printing method uses at least one nozzle print head to deposit at least one droplet of at least one bio-ink onto a depositing surface of the same receiving substrate as the laser print head.

Abstract: Bioprinting station (1) comprising:—a Bioprinting device (4) adapted to deposit a pattern of biological material (2) onto an area of interest (3a) of a substrate (3),—an imaging system (15) adapted to acquire an image of the substrate (3) and to reveal on the acquired image the area of interest (3a) with respect to a remaining part (3b) of the substrate (3), the acquired image of the substrate (3) being processed so as to detect the revealed area of interest (3a) on the acquired image and to determine the pattern corresponding to the area of interest (3a) detected on the acquired image.