Patents by Inventor Fabio Animati

Fabio Animati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • L-arabino-disaccharides of anthracyclines, processes for their preparation, and pharmaceutical compositions containing them
    Patent number: 6653289
    Abstract: The present invention refers to compounds of general formula (I), the pharmaceutically acceptable salts thereof, the processes for their preparation, and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: November 25, 2003
    Assignee: Menarini Ricerche S.p.A.
    Inventors: Fabio Animati, Marco Berettoni, Mario Bigioni, Amalia Cipollone, Carlo Alberto Maggi
  • S-fluoro-anthracyclines, processes for their preparation and pharmaceutical compositions containing them
    Patent number: 5814608
    Abstract: 8-fluoro-anthracyclines of formula (I) have anti-tumor activity. ##STR1## wherein: R is chosen in the group consisting of H, OH, OR.sub.4 wherein R.sub.4 is chosen in the group consisting of CHO, COCH.sub.3, acyl derivative of a carboxylic acid containing up to 6 carbon atoms;R.sub.1 is chosen in the group consisting of: H, OH, OCH.sub.3 ;R.sub.2 is chosen in the group consisting of: H, OH, NH.sub.2R.sub.3 is chosen in the group consisting of: H, OH, NH.sub.2, residue of formula (A) ##STR2## The compounds are characterized by having cis-stereochemistry between the groups 8--F and 9--OH. Their preparation and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: April 21, 1997
    Date of Patent: September 29, 1998
    Assignees: Bristol-Myers Squibb, S.p.A., A. Menarini Industrie Farmaceutiche Riunite S.R.L.
    Inventors: Fabio Animati, Federico Arcamone, Giuseppe Giannini, Paolo Lombardi, Edith Monteagudo
  • 3'-Deamino-4'-deoxy-4'-amino-8-fluoroanthracyclines
    Patent number: 5807835
    Abstract: New 8-fluoroanthracycline derivatives of formula I possessing antitumoral properties are described, together with their preparation and pharmaceutical compositions containing them.
    Type: Grant
    Filed: May 14, 1991
    Date of Patent: September 15, 1998
    Assignee: A. Menarini Industrie Farmaceutiche Riunite S.r.l.
    Inventors: Fabio Animati, Paolo Lombardi, Federico Arcamone
  • Antracycline disaccharides, process for their preparation, and pharmaceutical compositions containing them
    Patent number: 5801152
    Abstract: The present invention is referred to compounds of general formula (I) and (II), respectively ##STR1## their pharmaceutically acceptable salts, the process for their preparation, and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: March 28, 1996
    Date of Patent: September 1, 1998
    Assignees: A. Menarini Industrie Farmaceutiche Riunite S.r.l., Bristol-Myers Squibb S.p.A.
    Inventors: Fabio Animati, Paolo Lombardi, Frederico Arcamone, Amalia Cipollone
  • Distamycin a derivatives as anti-malarial agents
    Patent number: 5670534
    Abstract: The present invention relates to Distamycin compounds of formula (I), methods of use and their pharmaceutical compositions.
    Type: Grant
    Filed: February 16, 1996
    Date of Patent: September 23, 1997
    Assignees: A. Menarini Industrie Farmaceutice Reunite S.R.L., Bristol Myers Squibb S.P.A.
    Inventors: Fabio Animati, Federico Arcamone, Paolo Lombardi, Cristina Rossi
  • Poly 4-aminopyrrole-2-carboxyamide derivatives, and pharmaceutical compositions which contain them
    Patent number: 5472976
    Abstract: This invention relates to polyaminopyrrolecarboxyamide derivatives of general formula (I) and their pharmaceutically acceptable salts, in which A represents a chemical bond or an aromatic or heteroaromatic radical, and:if A is a chemical bond, R is hydrogen, alkyl, dialkylaminoalkyl, alkenyl, cycloalkyl, arylalkyl, arylalkenyl, haloalkyl, or an aromatic or heteroaromatic radical;whereas if A is an aromatic or heteroaromatic radical, R is nitro, amino or formylamino;n is 0 or a whole number between 1 and 4;Z is an alkylene or aromatic radical.
    Type: Grant
    Filed: August 6, 1993
    Date of Patent: December 5, 1995
    Assignees: A. Menarini Industrie Farmaceutiche Riunite S.r.l., Bristol-Meyers Squibb S.p.A.
    Inventors: Fabio Animati, Federico Arcamone, Giuseppe Giannini, Paolo Lombardi
  • Distamycin derivatives and process for their preparation
    Patent number: 4738980
    Abstract: Distamycin A derivatives of formula ##STR1## wherein R is (a)--NHR.sub.3, wherein R.sub.3 is(a')--CON(NO)R.sub.4, in which R.sub.4 is C.sub.1 -C.sub.4 alkyl either unsubstituted or substituted by halogen; or(b') --CO(CH.sub.2).sub.m --R.sub.5, in which R.sub.5 is halogen, oxiranyl, methyloxiranyl, aziridinyl, a group ##STR2## or a group ##STR3## and m is zero or an integer of 1 to 4; or (b) ##STR4## wherein either R.sub.6 and R.sub.7 are the same and are each oxiranemethyl, aziridinemethyl, or C.sub.2 -C.sub.4 alkyl 2-substituted by halogen or by a group --OSO.sub.2 R.sub.8, wherein R.sub.8 is C.sub.1 -C.sub.4 alkyl or phenyl, or one of R.sub.6 and R.sub.7 is hydrogen and the other is as defined above; andeach group R.sub.1 is, independently, hydrogen or C.sub.1 -C.sub.4 alkyl, and the pharmaceutically acceptable salts thereof.The compounds are useful as antiviral or antitumor agents.
    Type: Grant
    Filed: October 3, 1985
    Date of Patent: April 19, 1988
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Federico Arcamone, Nicola Mongelli, Fabio Animati