Patents by Inventor Fakrul A. A. Sayeed

Fakrul A. A. Sayeed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyethoxylated castor oil, process of making the same and formulations thereof
    Patent number: 5925776
    Abstract: Polyethoxylated castor oil with a low cation content are claimed, along with particular methods for achieving such low cation content polyethoxylated castor oil. One method of production of such a low cationic content polyethoxylated castor oil according to the invention is to pre-treat the polyethoxylated castor oil with a strong cationic exchange resin to remove a substantial portion of the cations present in an untreated polyethoxylated castor oil. The low cationic content polyethoxylated castor oil of the invention can then be utilized to prepare formulations of various agents which are found to be sensitive to the previously commercially available polyethoxylated castor oil (CREMOPHOR EL.RTM.).
    Type: Grant
    Filed: December 24, 1997
    Date of Patent: July 20, 1999
    Assignee: Schein Pharmacetical, Inc.
    Inventors: Aleksandr Nikolayev, Fakrul Sayeed, Rupa Iyer, Mitchell Garber, Robert C. Butterhof, Todd M. Hoyer, Marvin Samson
  • Cyclophosphamide
    Patent number: 5036060
    Abstract: A mannitol-free lyophilized formulation of cyclophosphamide is disclosed. Sodium chloride is present as an excipient.
    Type: Grant
    Filed: November 24, 1989
    Date of Patent: July 30, 1991
    Assignee: Fujisawa USA, Inc.
    Inventors: Abu S. Alam, Fakrul A. A. Sayeed, Kenneth J. Koziol, John N. Kapoor
  • Aqueous nitroglycerin injection and manufacturing process
    Patent number: 5001151
    Abstract: Nitroglycerin injection that is free of the customary organic solvents and has an extended shelf life of at least 1 year, consisting essentially of water, lactose, and nitroglycerin. Sodium chloride or dextrose may be added during manufacture or upon diluting with an infusion. Commercially safe manufacture and stable dispersion are assured by mixing lactose adsorbate, containing nitroglycerin, with water at high shear so that no nitroglycerin droplets coalesce. Stability is maintained by filtering and filling operations using nonreactive, nonleaching, nonadsorptive materials.
    Type: Grant
    Filed: June 28, 1989
    Date of Patent: March 19, 1991
    Assignee: Fujisawa USA, Inc.
    Inventors: Abu s. Alam, Utpal G. Joshi, Jairaj U. Mehta, Fakrul A. A. Sayeed, John N. Kapoor
  • Liquid cisplatin formulations
    Patent number: 4915956
    Abstract: This invention relates to an injectable, stable, sterile aqueous solution of cisplatin in a unit dosage form in a sealed container, the solution being suitable for administration by the injection thereof into man upon the removal thereof from the container, the solution consisting of water and cisplatin, said solution having a concentration of cisplatin between about 0.1 and about 1.3 mg/mL, and a pH in the range of about 3.5 to about 5.0, the solution being substantially free of dissolved oxygen.
    Type: Grant
    Filed: December 16, 1987
    Date of Patent: April 10, 1990
    Assignee: Lyphomed, Inc.
    Inventors: Abu S. Alam, Shaila Battu, Jairaj U. Mehta, Fakrul A. A. Sayeed, John N. Kapoor
  • Aqueous nitroglycerin injection and manufacturing process
    Patent number: 4879308
    Abstract: Nitroglycerin injection that is free of the customary organic solvents and has an extended shelf life of at least 1 year, consisting essentially of water, lactose, and nitroglycerin. Sodium chloride or dextrose may be added during manufacture or upon diluting with an infusion. Commerically safe manufacture and stable dispersion are assured by mixing lactose adsorbate, containing nitroglycerin, with water at high shear so that no nitroglycerin droplets coalesce. Stability is maintained by filtering and filling operations using nonreactive, nonleaching, nonadsorptive materials.
    Type: Grant
    Filed: August 11, 1987
    Date of Patent: November 7, 1989
    Assignee: LyphoMed, Inc.
    Inventors: Abu S. Alam, Utpal G. Joshi, Jairaj U. Mehta, Fakrul A. A. Sayeed, John N. Kapoor