Abstract: In certain embodiments, a method includes receiving, using one or more processors, a trigger expression. The method may include processing, using the one or more processors, the trigger expression, the trigger expression comprising a first one or more terms comprising a first one or more fields, to generate a reduced trigger expression. The reduced trigger expression includes a second one or more terms comprising a second one or more fields and being logically equivalent to the trigger expression. The method may include generating, using the one or more processors, a dynamic state machine by generating a first data structure comprising each of the second one or more fields, generating, based on the first data structure, an expanded trigger expression by adding one or more additional terms for possible state transitions, and generating, based on the expanded trigger expression, a second data structure.

Abstract: A display device is provided. The display device includes a pixel-displaying region, including: at least two pixels including a plurality of sub-pixels; and a light-shielding layer including a matrix portion and an enlarged portion, wherein the enlarged portion is disposed at an intersection of two of the adjacent sub-pixels and is adjacent to the matrix portion; wherein the matrix portion defines the sub-pixels, and a total area of the sub-pixels is defined as a first area and a ratio of an area of the enlarged portion to the first area is about 1.5% to 6%.

Abstract: A display device is provided. The display device includes a first substrate including a pixel-displaying region; a second substrate disposed opposite to the first substrate; a sealant disposed between the first substrate and the second substrate and disposed outside the pixel-displaying region; and a spacer wall disposed between the first substrate and the second substrate and disposed between the pixel-displaying region and the sealant, wherein a first side of the spacer wall is adjacent to the pixel-displaying region and a second side of the spacer wall is adjacent to the sealant, and a height of the first side is greater than a height of the second side.

Abstract: A display device is provided. The display device includes a pixel-displaying region, including: at least two pixels including a plurality of sub-pixels; and a light-shielding layer including a matrix portion and an enlarged portion, wherein the enlarged portion is disposed at an intersection of two of the adjacent sub-pixels and is adjacent to the matrix portion; wherein the matrix portion defines the sub-pixels, and a total area of the sub-pixels is defined as a first area and a ratio of an area of the enlarged portion to the first area is about 1.5% to 6%.

Abstract: In certain embodiments, a method includes receiving, using one or more processors, a trigger expression. The method may include processing, using the one or more processors, the trigger expression, the trigger expression comprising a first one or more terms comprising a first one or more fields, to generate a reduced trigger expression. The reduced trigger expression includes a second one or more terms comprising a second one or more fields and being logically equivalent to the trigger expression. The method may include generating, using the one or more processors, a dynamic state machine by generating a first data structure comprising each of the second one or more fields, generating, based on the first data structure, an expanded trigger expression by adding one or more additional terms for possible state transitions, and generating, based on the expanded trigger expression, a second data structure.

Abstract: In certain embodiments, a method includes receiving, using one or more processors, a trigger expression. The method may include processing, using the one or more processors, the trigger expression, the trigger expression comprising a first one or more terms comprising a first one or more fields, to generate a reduced trigger expression. The reduced trigger expression includes a second one or more terms comprising a second one or more fields and being logically equivalent to the trigger expression. The method may include generating, using the one or more processors, a dynamic state machine by generating a first data structure comprising each of the second one or more fields, generating, based on the first data structure, an expanded trigger expression by adding one or more additional terms for possible state transitions, and generating, based on the expanded trigger expression, a second data structure.

Abstract: Provided herein are antibodies, antigen-binding antibody fragments (Fabs), and other protein scaffolds, directed against human activated Protein C (aPC) with minimal binding to its zymogen Protein C (PC). Moreover, these aPC binding proteins could potentially block the anti-coagulant activity of aPC to induce coagulation. Therapeutic uses of these binders are described herein as are methods of panning and screening specific antibodies.

Abstract: Disclosed herein are anti-IL-13-R?2 antibodies and antibody drug conjugates and methods for preparing and using the same.

Abstract: A display device is provided. The display device includes a pixel-displaying region, including: at least two pixels including a plurality of sub-pixels; and a light-shielding layer including a matrix portion and an enlarged portion, wherein the enlarged portion is disposed at an intersection of two of the adjacent sub-pixels and is adjacent to the matrix portion; wherein the matrix portion defines the sub-pixels, and a total area of the sub-pixels is defined as a first area and a ratio of an area of the enlarged portion to the first area is about 1.5% to 6%.

Abstract: A display device is provided. The display device includes a first substrate including a pixel-displaying region; a second substrate disposed opposite to the first substrate; a sealant disposed between the first substrate and the second substrate and disposed outside the pixel-displaying region; and a spacer wall disposed between the first substrate and the second substrate and disposed between the pixel-displaying region and the sealant, wherein a first side of the spacer wall is adjacent to the pixel-displaying region and a second side of the spacer wall is adjacent to the sealant, and a height of the first side is greater than a height of the second side.

Abstract: The method of the invention provides for producing a heterologous protein in mammalian host cells having nucleic acid encoding Hepatitis B X protein and the heterologous protein, by growing mammalian host cells selected from the group consistng of HKB11, CHO, BHK21, C2C12, and HEK293 cells, by growing mammalian host cells in non-adherent suspension culture, or by growing mammalian host cells which contain nucleic acid providing exogenous X-box Binding Protein, XBP1s. The conditions should be such that HBx, exogenous XBP1s if present, and the heterologous protein are expressed by the mammalian cells. The invention includes compositions for carrying out the method.

Abstract: The method of the invention provides for producing a heterologous protein in mammalian host cells having nucleic acid encoding Hepatitis B X protein and the heterologous protein, by growing mammalian host cells selected from the group consisting of HKB11, CHO, BHK21, C2C12, and HEK293 cells, by growing mammalian host cells in non-adherent suspension culture, or by growing mammalian host cells which contain nucleic acid providing exogenous X-box Binding Protein, XBP1s. The conditions should be such that HBx, exogenous XBP1s if present, and the heterologous protein are expressed by the mammalian cells. The invention includes compositions for carrying out the method.

Abstract: In certain embodiments, a method includes receiving, using one or more processors, a trigger expression. The method may include processing, using the one or more processors, the trigger expression, the trigger expression comprising a first one or more terms comprising a first one or more fields, to generate a reduced trigger expression. The reduced trigger expression includes a second one or more terms comprising a second one or more fields and being logically equivalent to the trigger expression. The method may include generating, using the one or more processors, a dynamic state machine by generating a first data structure comprising each of the second one or more fields, generating, based on the first data structure, an expanded trigger expression by adding one or more additional terms for possible state transitions, and generating, based on the expanded trigger expression, a second data structure.

Abstract: The present invention relates to the generation of replication-competent viruses having therapeutic utility. The replication-competent viruses of the invention can express proteins useful in the treatment of disease.

Abstract: Provided herein are protein scaffolds, e.g. antibody mimetic scaffolds, comprising a three finger protein domain that specifically bind to target molecules, polynucleotides encoding such proteins, methods of using such proteins, and libraries of such scaffolds.

Abstract: The method of the invention provides for producing a heterologous protein in mammalian host cells having nucleic acid encoding Hepatitis B X protein and the heterologous protein, by growing mammalian host cells selected from the group consisting of HKB11, CHO, BHK21, C2C12, and HEK293 cells, by growing mammalian host cells in non-adherent suspension culture, or by growing mammalian host cells which contain nucleic acid providing exogenous X-box Binding Protein, XBP1s. The conditions should be such that HBx, exogenous XBP1s if present, and the heterologous protein are expressed by the mammalian cells. The invention includes compositions for carrying out the method.

Abstract: The present invention relates to the generation of replication-competent viruses having therapeutic utility. The replication-competent viruses of the invention can express proteins useful in the treatment of disease.

Abstract: An inhalable nasal powder preparation of insulin and its preparing process are provided. The powder inhalation is consisting of self-emulsifying freeze-dried powder and pharmaceutically acceptable carriers. The dry powder comprises insulin, fat(s), emulsifier(s), antioxidant(s), supporting agent(s), bio-gel adhesive(s), and pH modifier(s), wherein the emulsifier is a mixture of lecithin and Tween 80, and the amount of fat in the formulation is determined by the surface area and the particle diameter of oil droplet.

Abstract: An electronic device comprises a housing, a circuit board, a cover and a switch. The housing comprises an opening receiving a card. The circuit board is disposed in the housing. The cover is disposed on the housing corresponding to the opening. The switch is disposed on the circuit board, wherein when the cover is moved, the cover actuates the switch to control the circuit board.

Abstract: In a method of data transmission according to one embodiment of the invention, data transitions on adjacent conductors are separated in time. In a method of data transmission according to another embodiment of the invention, signals on adjacent conductive paths pass through different alternating sequences of inversions and regenerations. In a method of data transmission according to a further embodiment of the invention, data transitions having the same clock dependence are separated in space.