Patents by Inventor Fayaz Khazi

Fayaz Khazi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240138331
    Abstract: Stevia varieties with a high content of RebM, are disclosed Further provided are methods for producing Stevia plants having a high RebM content by negatively regulating certain genes selecting the resulting plants, and breeding with such plants to confer such desirable Reb M phenotypes to plant progeny.
    Type: Application
    Filed: December 13, 2023
    Publication date: May 2, 2024
    Applicants: PureCircle USA Inc., KeyGene N.V., The Coca-Cola Company
    Inventors: Avetik Markosyan, Seong Siang Ong, Runchun Jing, Tengfang Huang, Fayaz Khazi, Stephen Ezra Schauer, Indra Prakash, Alec Hayes
  • Publication number: 20240141372
    Abstract: The present disclosure provides compositions and methods for producing transgenic banana plants that exhibit increased resistance to Fusarium oxysporum f.sp. cubense Tropical Race 4 (TR4), and the banana plants and bananas so produced.
    Type: Application
    Filed: September 19, 2023
    Publication date: May 2, 2024
    Inventors: Matthew DiLeo, Jack Q. Wilkinson, Daniel Stauffer, Tomas Hasing, Tengfang Huang, Taylor Frazier-Douglas, Maria Angels de Luis Balaguer, Fayaz Khazi
  • Publication number: 20240132902
    Abstract: The present disclosure provides compositions and methods for producing transgenic plants and other organisms that exhibit increased production of mogroside compounds, in particular mogroside V, and the mogroside compounds, plants and plant parts so produced.
    Type: Application
    Filed: September 18, 2023
    Publication date: April 25, 2024
    Inventors: Tengfang Huang, Jack Q. Wilkinson, Anna Matthiadis, Devarshi Selote, Matthew Kilgore, Matthew DiLeo, Fayaz Khazi, Kevin Potter, Daniel Stauffer, Todd Rands
  • Publication number: 20240060079
    Abstract: Provided herein are methods for improving various traits in plants, such as in Vanilla sp. plants, by genetically-modifying the genome of plants, introducing heterologous sequences into the plants, or breeding plants with selected alleles. Such traits that can be improved by the methods and compositions of the present invention include an increase in levels of vanillin or one or more precursors thereof, reducing dehiscence, reducing the size of a rostellum or eliminating its presence, and increasing fungal resistance. Also disclosed herein are genetically-modified plants, extract from such plants or plant parts thereof, and methods of producing such plants or progeny thereof.
    Type: Application
    Filed: October 25, 2021
    Publication date: February 22, 2024
    Inventors: Fayaz Khazi, Tengfang Huang, Haibao Tang, Tomas Hasing, Alan Chambers
  • Publication number: 20240060078
    Abstract: The present disclosure presents a solution to producing mogrosides and mogroside-based sweeteners having low or no calorie. By using recombinant gene and plant transformation techniques, non-native genes encoding mogroside pathway enzymes are introduced/implemented into the genome of a plant hereby forming a transgenic plant, wherein the plant by the native genome thereof prior to transformation may not produce mogrosides naturally. Such transgenic plant and a progeny thereof are enabled to produce non-native mogrol precursors, mogrol, mogrosides, and/or metabolites or derivatives thereof.
    Type: Application
    Filed: March 17, 2021
    Publication date: February 22, 2024
    Applicant: The Coca-Cola Company
    Inventors: Alec J. HAYES, Christopher P. MERCOGLIANO, Tengfang HUANG, Fayaz KHAZI
  • Patent number: 11844323
    Abstract: Stevia varieties with a high content of RebM, are disclosed Further provided are methods for producing Stevia plants having a high RebM content by negatively regulating certain genes selecting the resulting plants, and breeding with such plants to confer such desirable Reb M phenotypes to plant progeny.
    Type: Grant
    Filed: March 22, 2022
    Date of Patent: December 19, 2023
    Assignees: PureCircle USA Inc., KeyGene N.V., The Coca-Cola Company
    Inventors: Avetik Markosyan, Seong Siang Ong, Runchun Jing, Tengfang Huang, Stephen Ezra Schauer, Fayaz Khazi, Indra Prakash, Alec Hayes
  • Publication number: 20230263121
    Abstract: Provided herein are methods for increasing the level of mogrosides in plants, such as in Cucurbitaceae family plants (e.g., in watermelon), by genetically-modifying such plants to modulate the expression of endogenous mogroside pathway genes. Also disclosed herein are plants with increased levels of mogrosides, extract (e.g., sweetener) from such plants, parts (e.g., juice, seed, pulp, etc.) from such plants, and methods of producing such plants.
    Type: Application
    Filed: March 30, 2021
    Publication date: August 24, 2023
    Inventors: Tengfang Huang, Jing Zhou, Hye-ran Lee, Jack Q. Wilkinson, Fayaz Khazi
  • Publication number: 20220210992
    Abstract: Stevia varieties with a high content of RebM, are disclosed Further provided are methods for producing Stevia plants having a high RebM content by negatively regulating certain genes selecting the resulting plants, and breeding with such plants to confer such desirable Reb M phenotypes to plant progeny.
    Type: Application
    Filed: March 22, 2022
    Publication date: July 7, 2022
    Applicant: PureCircle USA Inc.
    Inventors: Avetik Markosyan, Seong Siang Ong, Runchun Jing, Tengfang Huang, Stephen Ezra Schauer, Fayaz Khazi, Indra Prakash, Alec Hayes
  • Patent number: 11284577
    Abstract: Stevia varieties with a high content of RebM, are disclosed Further provided are methods for producing Stevia plants having a high RebM content by negatively regulating certain genes selecting the resulting plants, and breeding with such plants to confer such desirable Reb M phenotypes to plant progeny.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: March 29, 2022
    Assignees: PureCircle USA Inc., KeyGene N.V., The Coca-Cola Company
    Inventors: Avetik Markosyan, Seong Siang Ong, Runchun Jing, Tengfang Huang, Stephen Ezra Schauer, Fayaz Khazi, Indra Prakash, Alec Hayes
  • Publication number: 20200095597
    Abstract: Stevia varieties with a high content of RebM, are disclosed Further provided are methods for producing Stevia plants having a high RebM content by negatively regulating certain genes selecting the resulting plants, and breeding with such plants to confer such desirable Reb M phenotypes to plant progeny.
    Type: Application
    Filed: March 7, 2018
    Publication date: March 26, 2020
    Applicants: PureCircle USA Inc., KeyGene N.V., The Coca-Cola Company
    Inventors: Avetik Markosyan, Seong Siang Ong, Runchun Jing, Tengfang Huang, Stephen Ezra Schauer, Fayaz Khazi, Indra Prakash, Alec Hayes
  • Publication number: 20180344876
    Abstract: This invention relates to the field of therapeutics. Disclosed are methods of generating conditionally expressing erythropoietin under the control of an ecdysone receptor-based gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. The methods of the invention cause an in vivo increase in the expression of erythropoietin and an increase in the hematocrit or volume percentage of red blood cells in blood after administration of the ligand.
    Type: Application
    Filed: May 31, 2018
    Publication date: December 6, 2018
    Applicant: Intrexon Corporation
    Inventors: Jeremiah F. ROETH, Charles C. REED, Brandon CUTHERTSON, Sunil CHADA, William E. FOGLER, Fayaz KHAZI
  • Publication number: 20160317678
    Abstract: This invention relates to the field of therapeutics. Disclosed are methods of generating conditionally expressing erythropoietin under the control of an ecdysone receptor-based gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. The methods of the invention cause an in vivo increase in the expression of erythropoietin and an increase in the hematocrit or volume percentage of red blood cells in blood after administration of the ligand.
    Type: Application
    Filed: May 11, 2016
    Publication date: November 3, 2016
    Inventors: Jeremiah F. ROETH, Charles C. Reed, Brandon Cuthbertson, Sunil Chada, William E. Fogler, Fayaz Khazi
  • Patent number: 9402919
    Abstract: This invention relates to the field of therapeutics. Disclosed are methods of conditionally expressing erythropoietin under the control of an ecdysone receptor-based gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. The methods of the invention cause an in vivo increase in the expression of erythropoietin and an increase in the hematocrit or volume percentage of red blood cells in blood after administration of the ligand.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: August 2, 2016
    Assignee: Intrexon Corporation
    Inventors: Jeremiah F. Roeth, Charles C. Reed, Brandon Cuthbertson, Sunil Chada, William E. Fogler, Fayaz Khazi