Patents by Inventor Federico RICCARDI SIRTORI

Federico RICCARDI SIRTORI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purine and 3-deazapurine analogues as choline kinase inhibitors
    Patent number: 10683292
    Abstract: There are provided substituted purine and 3-deazapurine analogues, which modulate the activity of Choline Kinase (ChoK). The compounds of this invention are therefore useful in treating diseases caused by an altered choline metabolism, such as cancer, cell proliferative disorders, infectious diseases of different origin, immune-related disorders and neurodegenerative disorders. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: June 16, 2020
    Assignee: NERVIANO MEDICAL SCIENCES S.R.L.
    Inventors: Elena Casale, Emiliana Corti, Paola Gnocchi, Marcella Nesi, Sten Christian Orrenius, Francesca Quartieri, Federico Riccardi Sirtori
  • PURINE AND 3-DEAZAPURINE ANALOGUES AS CHOLINE KINASE INHIBITORS
    Publication number: 20190225615
    Abstract: There are provided substituted purine and 3-deazapurine analogues, which modulate the activity of Choline Kinase (ChoK). The compounds of this invention are therefore useful in treating diseases caused by an altered choline metabolism, such as cancer, cell proliferative disorders, infectious diseases of different origin, immune-related disorders and neurodegenerative disorders. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.
    Type: Application
    Filed: July 19, 2017
    Publication date: July 25, 2019
    Applicant: NERVIANO MEDICAL SCIENCES S.R.L.
    Inventors: Elena CASALE, Emliana CORTI, Paola GNOCCHI, Marcella NESI, Sten Christian ORRENIUS, Francesca QUARTIERI, Federico RICCARDI SIRTORI