Abstract: The invention belongs to the technical field of the molecular force field and particularly relates to a computing task management and analysis system for molecular force field parameter building and an operation method thereof. The system comprises a computing result analysis module and a computing task management module, the computing result analysis module is connected with the computing task management module, and the computing task management module is connected with a force field building computing server through a cloud computing interface. The operation method comprises: (1) selecting a molecular force field building computing templates; (2) selecting a computing task submitting platform and submitting computing tasks; (3) retrieving computing results; and (4) analyzing the computing results.

Abstract: This disclosure provides a system and method for user interaction in complex web 3D scenes, including a receiving module, a transmission module and a 3D model module. The receiving module receives molecular data. The transmission module analyzes the received molecular data and then enters the two branch modules at the same time. The branch modules include: a view layer unit: processing browser rendering and 3D model construction, the data generated by the branch will finally be presented on the browser page; a data layer unit: processing 3D picking-related business logic, and establishing a list of related model index information for atoms and covalent bonds in molecular data. The 3D model module: establishes a one-to-one correspondence between color and 3D model. This invention simplifies the display model of the molecule for the picking of web 3D molecular visualization and reduces the computational cost of the model data on the rendering.

Abstract: The systems and methods described herein relate to a dome of a gas turbine assembly configured to suppress pressure pulsations. The systems and methods provide a dome having an aperture configured to surround an injector assembly of a combustor. The dome having a front panel extending radially from the aperture. The systems and methods couple a first cavity to the front panel. The first cavity includes a series of ducts. A first duct of the series of ducts is configured to receive airflow into the first cavity from a compressor and a second set of ducts of the series of ducts and a third duct of the series of ducts are configured to direct airflow to the combustor from the first cavity, wherein the third duct has a larger diameter than the second set of ducts.

Abstract: Disclosed is a FER-type zeolite having at least silicon, aluminum, and oxygen as skeletal atoms, where a molar ratio between silicon atoms to aluminum atoms is 2-100:1. In addition, when 29Si solid nuclear magnetic resonance spectroscopy is used to analyze the zeolite, a peak area in the chemical shift range of ?90 ppm to ?110 ppm accounts for 25% or more of a peak area in the chemical shift range of ?90 ppm to ?125 ppm. Also disclosed are a preparation method for and an application of the FER zeolite.

Abstract: A system and method for performing accelerated k-space shift correction calibration scans for non-Cartesian trajectories is provided. The method can include applying an MRI sequence, performing a calibration scan based on the MRI sequence using the non-Cartesian trajectory to acquire k-space shift data, wherein one or more partitions are skipped during the calibration scan, interpolating the skipped one or more partitions using the k-space shift data from adjacent partitions, and calibrating the MRI system using the k-space shift data and the interpolated k-space shift data. In some embodiments, an acceleration factor Acc can be defined and the calibration scan acquires k-space shift data for only one partition in every Acc partitions.

Abstract: A system and method for performing accelerated k-space shift correction calibration scans for non-Cartesian trajectories is provided. The method can include applying an MRI sequence, performing a calibration scan based on the MRI sequence using the non-Cartesian trajectory to acquire k-space shift data, wherein one or more partitions are skipped during the calibration scan, interpolating the skipped one or more partitions using the k-space shift data from adjacent partitions, and calibrating the MRI system using the k-space shift data and the interpolated k-space shift data. In some embodiments, an acceleration factor Acc can be defined and the calibration scan acquires k-space shift data for only one partition in every Acc partitions.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.

Abstract: The disclosure relates to a method or a platform for hydrogel-based 3D fabrication, wherein the hydrogel is patterned with a programmable femtosecond light sheet with a power density of 0.1 to 100 TW/cm2.

Abstract: The present invention relates to antibodies and fragments thereof that target semaphorin 3A (Sema3A). More specifically, anti-Sema3A antibodies and methods of use for the treatment of various diseases or disorders are disclosed.

Abstract: A method for predicting a structural failure by a strength-criterion-driven peridynamic model is provided. By building a peridynamic model driven by the strength-criterion of structural materials and then applying geometric and material parameters and working conditions of a structure, a life period from a deformation to a complete break of the structure is predicted. The method is of a high reliability, a wide application range, and a high calculation efficiency. The method simulates an initiation and a propagation of multiple cracks on complex structures under complex load conditions until the structure is destroyed.

Abstract: The invention relates to agonistic TrkB binding molecules, methods for improving agonistic TrkB binders, their use in medicine, pharmaceutical compositions comprising the same, and methods of using the same as agents for treatment and/or prevention of diseases of the eye.

Abstract: This invention relates to binding molecules that bind specifically Vascular Endothelial Growth Factor (VEGF) and Tropomyosin receptor kinase B (TrkB) and their use in medicine, pharmaceutical compositions comprising the same, and methods of using the same as agents for treatment and/or prevention of diseases of the eye.

Abstract: Disclosed are an expansion tool assembly, comprising: an expandable tubular; a guide shoe partially inserted into and connected to the lower end of the expandable tubular; a sealing sleeve arranged in the expandable tubular and connected to the upper end of the guide shoe; an expansion assembly comprising an expansion cone and expansion seat disposed inside the expandable tubular, wherein the lower end of the expansion seat is connected with hooks, which can be rested on the upper end of the sealing sleeve; an upper joint that is connected to the upper end of the expansion seat and can be connected to a drill string. A force transfer path can be established via connection between the expansion seat and sealing sleeve, so that expandable tubular weight is borne on the drill string. Unintentional expansion of the expandable tubular, caused by interaction between expandable tubular and expansion cone, can be avoided.

Abstract: A method for predicting a structural failure by a strength-criterion-driven peridynamic model is provided. By building a peridynamic model driven by the strength-criterion of structural materials and then applying geometric and material parameters and working conditions of a structure, a life period from a deformation to a complete break of the structure is predicted. The method is of a high reliability, a wide application range, and a high calculation efficiency. The method simulates an initiation and a propagation of multiple cracks on complex structures under complex load conditions until the structure is destroyed.

Abstract: Systems and techniques for persistent calibration of an electronic device configured to implement an extended reality (XR) system involve estimating and validating visual-inertial odometry (VIO) calibration parameters during an active XR session of the electronic device. Validating the estimated VIO calibration parameters involves performing a strict calibration qualification of the estimated VIO calibration parameters using a thresholding module, machine learning module, or both. An initial calibration qualification is performed concurrently with the strict calibration qualification based on VIO performance. If the estimated VIO calibration parameters pass the strict calibration qualification and initial calibration qualification, they are stored for use to calibrate the device in future XR sessions. Persistent calibration of time alignment between the inertial management unit and the image sensor of the electronic device is also performed during active XR sessions upon detection of time alignment issues.

Abstract: The present disclosure discloses a shift register, a driving method thereof, a driving circuit, and a display device. The shift register includes an input circuit, a first control circuit, a second control circuit, and an output circuit. Signal shift output can be implemented through mutual cooperation between respective circuits. An output signal can be used as a light emitting control signal of a light emitting control transistor, or can be used as a gate scanning signal of a scanning control transistor.

Abstract: The present invention relates to antibodies and fragments thereof that target semaphorin 3A (Sema3A). More specifically, anti-Sema3A antibodies and methods of use for the treatment of various diseases or disorders are disclosed.

Abstract: A method for calculating physiological parameters includes: selecting a section of time domain signal corresponding to at least one signal of red light and infrared light obtained by sampling, and performing a conversion from time domain to frequency domain to obtain a corresponding frequency domain signal; selecting all rational frequency spectrum peak information, calculating energy information of selected reasonable frequency spectrum peaks, and forming a frequency spectrum peak energy ratio sequence; constructing a stability coefficient according to the frequency spectrum peak energy ratio sequence, and if the stability coefficient is low, constructing a compensation coefficient by using the frequency spectrum peak energy ratio sequence; and compensating for at least one of the time domain signal and the frequency domain signal by using the compensation coefficient, and calculating based on at least one of the compensated time domain signal and the frequency domain signal to obtain the physiological param