Abstract: A method of generating an integrated circuit includes: placing a plurality of electronic components on a layout floor plan to generate a placing layout of the integrated circuit; forming a clock tree upon the placing layout to generate a synthesis layout of the integrated circuit; routing the synthesis layout to generate a routed layout of the integrated circuit; performing a DRC process upon the routed layout to obtain a layout region with a systematic DRC violation; generating a plurality of prediction gains of the layout region according to a plurality of placement recipes respectively; and generating an adjusted routing layout of the integrated circuit by adjusting the layout region with the systematic DRC violation according to a target placement recipe in the plurality of placement recipes.

Abstract: The present invention provides compositions of bakuchiol (UP246) having low levels of impurities, particularly furanocoumarin impurities. The present invention further provides improved methods for the isolation, purification and analysis of compositions of bakuchiol. Finally, the present invention provides methods for using the purified bakuchiol compositions and formulations thereof for the prevention and treatment of various diseases and conditions mediated by cyclooxygenase (COX), lipoxygenase (LOX), minor inflammatory conditions and various microbial infections. The methods of this invention are comprised of administering to a host in need thereof an effective amount of the composition of this invention together with a pharmaceutically acceptable carrier.

Abstract: Methods for treating excess pigmentation, including treatment of post inflammatory hyperpigmentation (PIH), are disclosed. The disclosed methods comprise administration of a composition comprising bakuchiol substantially free of furanocoumarins to a mammal. Compositions comprising bakuchiol and methods for their preparation are also disclosed.

Abstract: A method for obtaining contact information includes obtaining a contact name entered by a user through a dialing interface and searching a local database according to the contact name to determine whether basic contact information corresponding to the contact name is stored in the local database. If stored, the basic contact information stored in the local database is obtained. If the basic contact information is not stored in the local database, searching a database server on a network is performed to determine whether the basic contact information is stored in the database server, the basic contact information is obtained from the database server when the basic contact information is stored in the database server, and the obtained basic contact information is stored in the local database. The method also includes establishing a communication connection with a contact corresponding to the contact name by using the obtained basic contact information.

Abstract: A field-programmable gate array (FPGA)-based real-time processing system applied to underwater acoustic positioning and realizing reconfigurability and multiple output is provided. The system includes a multi-interface control and command parsing module for automatically completing sample information transmission and command parsing; a finite-state machine (FSM) of sample management for calculating related data and completing splitting, flipping and writing of a sample; a parallel correlation processor group for completing, in parallel, high-performance processing operations regarding a plurality of targets; and a multiple output data former for simultaneously realizing data formation of a multiple output result and outputting a flag bit signal to the outside. A FPGA-based real-time processing control method is also provided that is applied to underwater acoustic positioning and realizing reconfigurability and multiple output.

Abstract: A FPGA-based intelligent storage control system is provided that includes a FLASH main controller; a FLASH command former and an address generator with a memory function, for generating level signal of cross clock domain and automatically avoiding out-of-bounds writing. A configuration data former provides for driving and controlling a configuration writing in function by a writing configuration drive signal. An automatic reading configurator provides automatic configuration reading by internal drive signal to drive. A main data and auxiliary data former provides continuous storage of main data according to ping-pong operation for unequal width RAM operation. A FLASH data reading buffer and a multi-interface external drive module are also present. The system is applicable to an unmanned underwater vehicle and underwater acoustic equipment.

Abstract: A data storage device is disclosed comprising an actuator configured to actuate a head over a disk surface, and a vibration sensor configured to generate a vibration signal (VS). Control circuitry comprising a servo control system having a torque rejection curve (TRC) configured to control the actuator is configured to measure a position error signal (PES) of the head, and measure the VS output by the vibration sensor. A feed-forward compensator is configured based on PES/VS/TRC. While seeking the head across the disk surface, the VS is processed using the feed-forward compensator to generate a feed-forward compensation during a settle interval of the seek, and the actuator is controlled using the feed-forward compensation during the settle interval.

Abstract: A method of generating an integrated circuit includes: placing a plurality of electronic components on a layout floor plan to generate a placing layout of the integrated circuit; forming a clock tree upon the placing layout to generate a synthesis layout of the integrated circuit; routing the synthesis layout to generate a routed layout of the integrated circuit; performing a DRC process upon the routed layout to obtain a layout region with a systematic DRC violation; generating a plurality of prediction gains of the layout region according to a plurality of placement recipes respectively; and generating an adjusted routing layout of the integrated circuit by adjusting the layout region with the systematic DRC violation according to a target placement recipe in the plurality of placement recipes.

Abstract: The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

Abstract: The present invention provides compositions of bakuchiol (UP246) having low levels of impurities, particularly furanocoumarin impurities. The present invention further provides improved methods for the isolation, purification and analysis of compositions of bakuchiol. Finally, the present invention provides methods for using the purified bakuchiol compositions and formulations thereof for the prevention and treatment of various diseases and conditions mediated by cyclooxygenase (COX), lipoxygenase (LOX), minor inflammatory conditions and various microbial infections. The methods of this invention are comprised of administering to a host in need thereof an effective amount of the composition of this invention together with a pharmaceutically acceptable carrier.

Abstract: Compositions are disclosed herein that comprise a mixture of at least one Albizia extract and a Magnolia extract. In some embodiments, the composition comprises a mixture of at least one Albizia extract enriched for one or more macrocyclic alkaloids and at least one Magnolia extract enrich for one or more lignans.

Abstract: Methods for treating excess pigmentation, including treatment of post inflammatory hyperpigmentation (PIH), are disclosed. The disclosed methods comprise administration of a composition comprising bakuchiol substantially free of furanocoumarins to a mammal. Compositions comprising bakuchiol and methods for their preparation are also disclosed.

Abstract: Compositions are disclosed herein that comprise a mixture of at least one Albizia extract and a Magnolia extract. In some embodiments, the composition comprises a mixture of at least one Albizia extract enriched for one or more macrocyclic alkaloids and at least one Magnolia extract enrich for one or more lignans.

Abstract: The present disclosure provides a mixture of sugar apple and rosemary extracts, optionally in combination with prickly ash extract, for use as skin care compositions.

Abstract: The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

Abstract: The present disclosure provides a mixture of sugar apple and rosemary extracts, optionally in combination with prickly ash extract, for use as skin care compositions.

Abstract: Methods for treating excess pigmentation, including treatment of post inflammatory hyperpigmentation (PIH), are disclosed. The disclosed methods comprise administration of a composition comprising bakuchiol substantially free of furanocoumarins to a mammal. Compositions comprising bakuchiol and methods for their preparation are also disclosed.

Abstract: Methods for treating excess pigmentation, including treatment of post inflammatory hyperpigmentation (PIH), are disclosed. The disclosed methods comprise administration of a composition comprising bakuchiol substantially free of furanocoumarins to a mammal. Compositions comprising bakuchiol and methods for their preparation are also disclosed.

Abstract: A data storage device is disclosed comprising a first actuator configured to actuate a first head over a first disk surface, and a second actuator configured to actuate a second head over a second disk surface. A seeking control signal is generated and used to control the first actuator to seek the first head over the first disk surface. The seeking control signal is filtered with a decoupler to generate a decoupler control signal, wherein the decoupler comprises a nominal decoupler and an adaptive decoupler. A tracking control signal is generated based on the decoupler control signal, and the tracking control signal is used to control the second actuator in order to access the second disk surface using the second head.

Abstract: The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.