Abstract: The present invention relates to Compounds of Formula I: I and pharmaceutically acceptable salts or prodrug thereof. The present invention also relates to compositions comprising at least one compound of Formula I, and methods of using the compounds of Formula I for treatment or prophylaxis of cardiometabolic diseases including high blood pressure, heart failure, kidney disease, and diabetes in a subject.

Abstract: The present invention relates to Compounds of Formula I: I and pharmaceutically acceptable salts or prodrug thereof. The present invention also relates to compositions comprising at least one compound of Formula I, and methods of using the compounds of Formula I for treatment of cardiometabolic diseases including high blood pressure, heart failure, kidney disease, and diabetes in a subject.

Abstract: The present disclosure provides, inter alia, methods for treating or ameliorating the effects of a cancer in a subject in need thereof by combining a radiosensitizer such as a ferroptosis inducer with radiation. Methods for identifying and treating a subject with a cancer that is resistant to radiotherapy, methods for enhancing the anti-tumor effect of radiation in a subject undergoing radiotherapy, and methods for enhancing the effect of radiation on a cancer cell are also provided.

Abstract: A semiconductor package comprises a lead frame, a chip, and a molding encapsulation. The lead frame comprises one or more die paddles, a first plurality of leads, and a second plurality of leads. A respective end surface of each lead of the first plurality of leads and the second plurality of leads is plated with a metal. A first respective window on a first side of each lead of the first plurality of leads and the second plurality of leads is not plated with the metal. A second respective window on a second side of each lead of the first plurality of leads and the second plurality of leads is not plated with the metal. A method for fabricating a semiconductor package comprises the steps of providing a lead frame array, mounting a chip, forming a molding encapsulation, and applying a cutting process or a punching process.

Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

Abstract: A directional and timing control circuit is provided. the circuit includes a main control chip, a power supply module to supply power to the main control chip, a driver module configured to receive a control command from the main control chip and to control a motor according to the control command, a Hall module configured to detect an operation direction of the motor and transmit an operation direction signal to the main control chip, and a zero-crossing detection module configured to detect a zero-crossing cycle of the alternating current power supply to thereby obtain a current utility frequency of the alternating current power supply as a timing frequency of the main control chip, the zero-crossing detection module including an input terminal connected to the alternating current power supply and an output terminal connected to a phase detection terminal of the main control chip.

Abstract: The present application discloses to a schedule information acquiring method, an apparatus, a device, a storage medium and a program product, which relates to the artificial intelligence field. The method includes: acquiring multiple subscription identification information respectively corresponding to multiple service instances; for each subscription identification information corresponding to each service instance, requesting schedule information corresponding to the subscription identification information from a first server end through the service instance; and sending the schedule information to a terminal corresponding to the subscription identification information. The method realizes synchronization of schedule information.

Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

Abstract: This application provides a trace chain information query method, including: receiving, by a trace chain server, first trace chain information sent by a first service node and second trace chain information sent by a second service node, where the first service node is a service node in a first trace chain, the second service node is a service node in a second trace chain, both the first trace chain and the second trace chain are generated as triggered by a same user operation, the first trace chain information includes a group identifier, the second trace chain information includes the group identifier, and the group identifier is used to indicate the user operation; and finding, by the trace chain server, the first trace chain information and the second trace chain information based on the group identifier.

Abstract: The disclosure is about a method capable of realizing the preparation and in-situ separation of the oligomeric ricinoleate, which uses the ricinoleic acid as raw material, and uses a protonic acid-type ionic liquid as a catalyst to cause the dehydration and esterification reactions between ricinoleic acid molecules. By continuously distilling out the generated water under a reduced pressure, the oligomeric ricinoleate with a polymerization degree of 2 to 10 is obtained. After the reaction, a method of washing with water or static stratification is selected to recover the catalyst according to the miscibility of the catalyst and reaction system. In his disclosure, renewable raw materials are used, the process is clean and pollution-free, and the operation is simple.

Abstract: A joint for a swimming pool frame, and a swimming pool including the joint are provided. The joint includes a joint body including a leg pipe holder configured to have a leg pipe of the swimming pool frame inserted into the leg pipe holder. The joint also includes a side pipe holder configured to have a side pipe of the swimming pool frame inserted in the side pipe holder. A locking hole is formed through the side pipe holder. The joint body also includes a locking part including a locking pin configured to extend through the locking hole and through a corresponding connecting hole in the side pipe, thereby holding the side pipe to the side pipe holder.

Abstract: The present invention discloses an intelligent range hood and a control method thereof, which comprises a housing, a fan (4), a smoke collecting hood (3), a smoke guide plate (6), a controller and a sensor (8) for detecting concentration of smoke and/or vapor inside or outside the housing. The sensor (8) outputs an electrical signal to the controller; and, the controller controls rotation speed of the fan motor (5) and position of the smoke guide plate (6) according to the signal received from the sensor (8). The controller not only can automatically adjust the rotation speed of the fan motor (5) so as to allow the air volume of the fan (4) to adapt to the working condition of the range hood in real time, but also can adjust the air inlet area and the distance between the negative pressure region and the smoke source by moving the smoke guide plate (6) up and down, so as to adapt the change in the working condition.

Abstract: This application provides an interference measurement method and apparatus. A second functional entity of an interference-generating node sends, by using one or more beams corresponding to a reference signal resource identifier of a first functional entity of the interference-generating node, a reference signal used for interference measurement, so that an interfered node can perform interference measurement.

Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

Abstract: Provided is a power grid adjustment method based on a load of a variable frequency air conditioner. The method includes: establishing a mathematical simulation model of a virtual synchronous motor in a variable frequency air conditioner controller; establishing a virtual inertia control segment and a droop control segment of power grid adjustment according to the mathematical simulation model; obtaining a reference value ?? of rotation speed variation of a compressor by the virtual inertia control segment; obtaining a reference value ?ref of rotational angular frequency of the compressor by the droop control segment; and inputting a sum of the reference value ?ref of rotational angular frequency of the compressor and the reference value ?? of rotation speed variation of the compressor into a field-oriented controller (FOC) to control rotation of a motor.

Abstract: The present invention provides a breeding method for tetraploid ricinus communis. The method comprises: collecting a ricinus communis germplasm resource, performing morphologic character analysis and chromosome ploidy identification, selecting good diploid varieties, carrying out mutagenesis by using colchicine and oryzalin; performing chromosome ploidy identification on F1 generation seeds, selecting homozygous tetraploids, and performing economic character analysis and identification on the F2 generation, so as to breed good tetraploid ricinus communis.

Abstract: A method implemented by a network element (NE) in a distributed system, the method comprising tracing an execution of a program in the distributed system to produce a record of the execution of the program, wherein the record indicates states of shared resources at various times during the execution of the program, identifying a vulnerable operation that occurred during the program execution based on the record, wherein the record indicates that a first shared resource of the shared resources is in a flawed state after a node that caused the first shared resource to be in the flawed state crashed, and determining that the vulnerable operation results in a time of fault (TOF) bug based on performing a fault-tolerance mechanism.

Abstract: A method for detecting distributed concurrency errors in a distributed cloud computing system includes tracing operations that access objects in functions involving inter-process messaging, applying a set of happens-before rules to the traced operations. Analyzing the traced operations to identify concurrent operations that access a common object to generate a list of potential distributed concurrency errors (DCbugs). Pruning the list of DCbugs to remove DCbugs having only local effect and that do not generate run-time errors.

Abstract: Described herein are systems and methods for distributed concurrency (DC) bug detection. The method includes identifying a plurality of nodes in a distributed computing cluster; identifying a plurality of messages to be transmitted during execution of an application by the distributed computing cluster; determining a set of orderings of the plurality of messages for DC bug detection, the set of orderings determined based upon the plurality of nodes and the plurality of messages; removing a subset of the orderings from the set of orderings based upon one or more of a state symmetry algorithm, a disjoint-update independence algorithm, or a zero-crash-impact reordering algorithm; and performing DC bug detection testing using the set of orderings after the subset of the orderings is removed from the set of orderings.

Abstract: A heat source sensor includes a plurality of first wires extending in a first direction, a plurality of second wires extending in a second direction different from the first direction and crossing the plurality of first wires, and a plurality of nodes. Each node is defined at a crossing of a first wire of the plurality of first wires and a second wire of the plurality of second wires. The first wire is secured to the second wire at the node. Each node of the plurality of nodes defines a measurement point of the heat source sensor, with a difference in thermoelectric electromotive forces between two nodes of the plurality of nodes indicative of a temperature difference between the two nodes.