Patents by Inventor Ferdinando Bruno
Ferdinando Bruno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8431176Abstract: Disclosed is a separated fraction of a reaction product of an enzymatically catalyzed polymerization of a flavonoid. The separated fraction is highly resistant to oxidation and is useful in numerous applications such as an antioxidant in food products and medical applications.Type: GrantFiled: March 8, 2010Date of Patent: April 30, 2013Assignee: The United States of America as Represented by the Secretary of the ArmyInventors: Kenneth Racicot, Nicole Favreau, Ferdinando Bruno
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Patent number: 7718112Abstract: Nanometer scale structures, and methods of making the same are disclosed.Type: GrantFiled: August 23, 2005Date of Patent: May 18, 2010Assignees: University of Massachusetts, The United States of America as Represented by the Secretary of the ArmyInventors: Christopher Drew, Ferdinando Bruno, Lynne Ann Samuelson, Jayant Kumar
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Patent number: 7510739Abstract: An assembled hematin is formed by depositing hematin on an electrically charged substrate in one or more layers alternating with one or more layers of polyelectrolyte, preferably a cationic polymer. In a method for polymerizing an aromatic monomer, the assembled hematin is contacted with the monomer and a template, preferably an anionic polymer. In a method for polymerizing aniline, the aniline, sulfonated multi walled carbon nano tubes, PEG hematin and a reaction initiator are dispersed in water.Type: GrantFiled: April 21, 2005Date of Patent: March 31, 2009Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Ferdinando Bruno, Lynne A. Samuelson, Ramaswamy Nagarajan, Jayant Kumar, Michael Sennett
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Publication number: 20080090103Abstract: Hematin, a hydroxyferriprotoporphyrin, is derivatized with one or more non-proteinaceous amphipathic groups. The derivatized hematin can serve as a mimic of horseradish peroxidase in polymerizing aromatic monomers, such as aromatic compounds. These derivatized hematins can also be used as catalysts in polymerizing aromatic monomers, and can exhibit significantly greater catalytic activity than underivatized hematin in acidic solutions. In one embodiment, polymerization is in the presence of a template, along which aromatic monomers align. An assembled hematin includes alternating layers of hematin and a polyelectrolyte, which are deposited on an electrically charged substrate. Assembled hematin can also be used to polymerize aromatic monomers.Type: ApplicationFiled: September 26, 2007Publication date: April 17, 2008Applicants: University of Massachusetts Lowell, Government of the United States, as Represented by the Secretary of the ArmyInventors: Sukant Tripathy, Susan Tripathy, Lynne Samuelson, Ferdinando Bruno, Sucharita Roy, Ramaswamy Nagarajan, Jayant Kumar, Bon-Cheol Ku, Soo-Hyoung Lee
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Patent number: 7358327Abstract: An assembled hematin is formed by depositing hematin on an electrically charged substrate in one or more layers alternating with one or more layers of polyelectrolyte, preferably a cationic polymer. In a method for polymerizing an aromatic monomer, the assembled hematin is contacted with the monomer and a template, preferably an anionic polymer. In a method for polymerizing aniline, the aniline, sulfonated multi walled carbon nano tubes, PEG hematin and a reaction initiator are dispersed in water.Type: GrantFiled: April 21, 2005Date of Patent: April 15, 2008Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Ferdinando Bruno, Lynne A. Samuelson, Ramaswamy Nagarajan, Jayant Kumar, Michael Sennett
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Patent number: 7344751Abstract: An assembled hematin is formed by depositing hematin on an electrically charged substrate in one or more layers alternating with one or more layers of polyelectrolyte, preferably a cationic polymer. In a method for polymerizing an aromatic monomer, the assembled hematin is contacted with the monomer and a template, preferably an anionic polymer. In a method for polymerizing aniline, the aniline, sulfonated multi walled carbon nano tubes, PEG hematin and a reaction initiator are dispersed in water.Type: GrantFiled: April 21, 2005Date of Patent: March 18, 2008Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Ferdinando Bruno, Lynne A. Samuelson, Ramaswamy Nagarajan, Jayant Kumar, Michael Sennett
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Patent number: 7332297Abstract: The invention relates to a novel method for enzymatic polymerization which includes (1) obtaining a reaction mixture including a monomer, a template, and an enzyme; and (2) incubating the reaction mixture for a time and under conditions sufficient for the monomer to align along the template and polymerize to form a polymer-template complex. The template can be a micelle, a borate-containing electrolyte, or lignin sulfonate. Such a complex possesses exceptional electrical and optical stability, water solubility, and processibility, and can be used in applications such as light-weight energy storage devices (e.g., rechargeable batteries), electrolytic capacitors, anti-static and anti-corrosive coatings for smart windows, and biological sensors.Type: GrantFiled: March 14, 2003Date of Patent: February 19, 2008Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Lynne A. Samuelson, Ferdinando Bruno, Susan Tripathy, legal representative, Ramaswamy Nagarajan, Jayant Kumar, Wei Liu, Sukant K. Tripathy
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Patent number: 7309582Abstract: The invention relates to a novel method for enzymatic polymerization which includes (1) obtaining a reaction mixture including a monomer, a template, and an enzyme; and (2) incubating the reaction mixture for a time and under conditions sufficient for the monomer to align along the template and polymerize to form a polymer-template complex. The template can be a micelle, a borate-containing electrolyte, or lignin sulfonate. Such a complex possesses exceptional electrical and optical stability, water solubility, and processibility, and can be used in applications such as light-weight energy storage devices (e.g., rechargeable batteries), electrolytic capacitors, anti-static and anti-corrosive coatings for smart windows, and biological sensors.Type: GrantFiled: March 14, 2003Date of Patent: December 18, 2007Assignee: United States of America as represented by the Secretary of the ArmyInventors: Lynne A. Samuelson, Ferdinando Bruno, Susan Tripathy, legal representative, Ramaswamy Nagarajan, Jayant Kumar, Wei Liu, Sukant K. Tripathy, deceased
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Publication number: 20070284303Abstract: Nanometer scale structures, and methods of making the same are disclosed.Type: ApplicationFiled: August 23, 2005Publication date: December 13, 2007Inventors: Christopher Drew, Ferdinando Bruno, Lynne Samuelson, Jayant Kumar
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Publication number: 20070154430Abstract: Antioxidant polymers of the present invention comprise repeat units that include one or both of Structural Formulas (I) and (II): wherein: R is —H or a substituted or unsubstituted alkyl, acyl or aryl group; Ring A is substituted with at least one tert-butyl group or substituted or unsubstituted n-alkoxycarbonyl group; Ring B is substituted with at least one —H and at least one tert-butyl group or substituted or unsubstituted n-alkoxycarbonyl group; Rings A and B are each optionally substituted with one or more groups selected from the group consisting of —OH, —NH, —SH, a substituted or unsubstituted alkyl or aryl group, and a substituted or unsubstituted alkoxycarbonyl group; n is an integer equal to or greater than 2; and p is an integer equal to or greater than 0. The invention also includes methods of using and preparing these polymers.Type: ApplicationFiled: February 27, 2007Publication date: July 5, 2007Inventors: Ashok Cholli, Vijayendra Kumar, Javant Kumar, Virinder Parmar, Lynne Samuelson, Ferdinando Bruno
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Publication number: 20070154608Abstract: Antioxidant polymers of the present invention comprise repeat units that include one or both of Structural Formulas (I) and (II): wherein: R is —H or a substituted or unsubstituted alkyl, acyl or aryl group; Ring A is substituted with at least one tert-butyl group or substituted or unsubstituted n-alkoxycarbonyl group; Ring B is substituted with at least one —H and at least one tert-butyl group or substituted or unsubstituted n-alkoxycarbonyl group; Rings A and B are each optionally substituted with one or more groups selected from the group consisting of —OH, —NH, —SH, a substituted or unsubstituted alkyl or aryl group, and a substituted or unsubstituted alkoxycarbonyl group; n is an integer equal to or greater than 2; and p is an integer equal to or greater than 0. The invention also includes methods of using and preparing these polymers.Type: ApplicationFiled: February 27, 2007Publication date: July 5, 2007Inventors: Ashok Cholli, Vijayendra Kumar, Javant Kumar, Virinder Parmar, Lynne Samuelson, Ferdinando Bruno
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Publication number: 20070154720Abstract: Antioxidant polymers of the present invention comprise repeat units that include one or both of Structural Formulas (I) and (II): wherein: R is —H or a substituted or unsubstituted alkyl, acyl or aryl group; Ring A is substituted with at least one tert-butyl group or substituted or unsubstituted n-alkoxycarbonyl group; Ring B is substituted with at least one —H and at least one tert-butyl group or substituted or unsubstituted n-alkoxycarbonyl group; Rings A and B are each optionally substituted with one or more groups selected from the group consisting of —OH, —NH, —SH, a substituted or unsubstituted alkyl or aryl group, and a substituted or unsubstituted alkoxycarbonyl group; n is an integer equal to or greater than 2; and p is an integer equal to or greater than 0. The invention also includes methods of using and preparing these polymers.Type: ApplicationFiled: February 27, 2007Publication date: July 5, 2007Inventors: Ashok Cholli, Vijayendra Kumar, Jayant Kumar, Virinder Parmar, Lynne Samuelson, Ferdinando Bruno
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Patent number: 7230071Abstract: A method for polymerizing electronic and photonic polymers, wherein an aromatic monomer is combined with a hematin catalyst derivatized with at least one non-proteinaceous amphipathic group, and a peroxide initiator, and employing a template, wherein the aromatic monomer aligns along the template and polymerizes to form a complex comprising the polymerized monomer and the template.Type: GrantFiled: February 9, 2004Date of Patent: June 12, 2007Assignee: United States of America as represented by the Secretary of the ArmyInventors: Ferdinando Bruno, Lynne A. Samuelson, Ramaswamy Nagarajan, Jayant Kumar
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Patent number: 7186792Abstract: A method for polymerizing electronic and photonic polymers, wherein an aromatic monomer is combined with a hematin catalyst derivatized with at least one non-proteinaceous amphipathic group, and a peroxide initiator, and employing a template, wherein the aromatic monomer aligns along the template and polymerizes to form a complex comprising the polymerized monomer and the template.Type: GrantFiled: May 2, 2005Date of Patent: March 6, 2007Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Ferdinando Bruno, Lynne A. Samuelson, Ramaswamy Nagarajan, Jayant Kumar
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Patent number: 7186791Abstract: A method for polymerizing electronic and photonic polymers, wherein an aromatic monomer is combined with a hematin catalyst derivatized with at least one non-proteinaceous amphipathic group, and a peroxide initiator, and employing a template, wherein the aromatic monomer aligns along the template and polymerizes to form a complex comprising the polymerized monomer and the template.Type: GrantFiled: May 2, 2005Date of Patent: March 6, 2007Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Ferdinando Bruno, Lynne A. Samuelson, Ramaswamy Nagarajan, Jayant Kumar
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Publication number: 20070021587Abstract: Hematin, a hydroxyferriprotoporphyrin, is derivatized with one or more non-proteinaceous amphipathic groups. The derivatized hematin can serve as a mimic of horseradish peroxidase in polymerizing aromatic monomers, such as aromatic compounds. These derivatized hematins can also be used as catalysts in polymerizing aromatic monomers, and can exhibit significantly greater catalytic activity than underivatized hematin in acidic solutions. In one embodiment, polymerization is in the presence of a template, along which aromatic monomers align. An assembled hematin includes alternating layers of hematin and a polyelectrolyte, which are deposited on an electrically charged substrate. Assembled hematin can also be used to polymerize aromatic monomers.Type: ApplicationFiled: January 23, 2006Publication date: January 25, 2007Inventors: Sukant Tripathy, Susan Tripathy, Lynne Samuelson, Ferdinando Bruno, Sucharita Roy, Ramaswamy Nagarajan, Jayant Kumar, Bon-Cheol Ku, Soo-Hyoung Lee
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Patent number: 7056675Abstract: A conductive polymer is formed enzymatically in the presence of a polynucleotide template. The method includes combining at least one redox monomer with a polynucleotide template and a redox enzyme, such as horseradish peroxidase, to form a reaction mixture. The monomer aligns along the template before or during the polymerization. Therefore, the polynucleotide template thereby affects the molecular weight and conformation of the conductive polymer. When the conductive polymer is complexed to a polynucleotide duplex, the conformation of the polynucleotide duplex can be modulated by changing the oxidation state of the conductive polymer.Type: GrantFiled: October 5, 2004Date of Patent: June 6, 2006Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Lynne A. Samuelson, Ferdinando Bruno, Susan Tripathy, legal representative, Ramaswamy Nagarajan, Jayant Kumar, Wei Liu, Sukant K. Tripathy, deceased
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Publication number: 20060078756Abstract: An assembled hematin is formed by depositing hematin on an electrically charged substrate in one or more layers alternating with one or more layers of polyelectrolyte, preferably a cationic polymer. In a method for polymerizing an aromatic monomer, the assembled hematin is contacted with the monomer and a template, preferably an anionic polymer. In a method for polymerizing aniline, the aniline, sulfonated multi walled carbon nano tubes, PEG hematin and a reaction initiator are dispersed in water.Type: ApplicationFiled: February 9, 2004Publication date: April 13, 2006Inventors: Ferdinando Bruno, Lynne Samuelson, Ramaswamy Nagarajan, Jayant Kumar, Michael Sennett
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Patent number: 7022420Abstract: An assembled hematin is formed by depositing hematin on an electrically charged substrate in one or more layers alternating with one or more layers of polyelectrolyte, preferably a cationic polymer. In a method for polymerizing an aromatic monomer, the assembled hematin is contacted with the monomer and a template, preferably an anionic polymer. In a method for polymerizing aniline, the aniline, sulfonated multi walled carbon nano tubes, PEG hematin and a reaction initiator are dispersed in water.Type: GrantFiled: February 9, 2004Date of Patent: April 4, 2006Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Ferdinando Bruno, Lynne A. Samuelson, Ramaswamy Nagarajan, Jayant Kumar, Michael Sennett
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Publication number: 20060041110Abstract: A conductive polymer is formed enzymatically in the presence of a polynucleotide template. The method includes combining at least one redox monomer with a polynucleotide template and a redox enzyme, such as horseradish peroxidase, to form a reaction mixture. The monomer aligns along the template before or during the polymerization. Therefore, the polynucleotide template thereby affects the molecular weight and conformation of the conductive polymer. When the conductive polymer is complexed to a polynucleotide duplex, the conformation of the polynucleotide duplex can be modulated by changing the oxidation state of the conductive polymer.Type: ApplicationFiled: December 19, 2002Publication date: February 23, 2006Inventors: Lynne Samuelson, Ferdinando Bruno, Sukant Tripathy, Susan Tripathy, Ramaswamy Nagarajan, Jayant Kumar, Wei Liu