Patents by Inventor Fernando Albericio

Fernando Albericio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Support material for solid phase organic synthesis
    Patent number: 6566494
    Abstract: A support material for solid phase synthesis is provided having an amine-containing organic group attached to it through a linker.
    Type: Grant
    Filed: May 11, 1999
    Date of Patent: May 20, 2003
    Assignee: Regents of the University of Minnesota
    Inventors: Knud J. Jensen, George Barany, Micheal F. Songster, Fernando Albericio, Jordi Alsina, Josef Vágner
  • Support material for solid phase organic synthesis
    Patent number: 5917015
    Abstract: A support material for solid phase synthesis is provided having an amine-containing organic group attached to it through a linker.
    Type: Grant
    Filed: June 18, 1996
    Date of Patent: June 29, 1999
    Assignee: Regents of the University of Minnesota
    Inventors: Knud J. Jensen, George Barany, Micheal F. Songster, Fernando Albericio, Jordi Alsina, Josef Vagner
  • Automated allyl deprotection in solid-phase synthesis
    Patent number: 5861351
    Abstract: A method for removing an allyl protecting group from an allyl-protected derivative of a biologically relevant amino acid is disclosed. One relevant aspect of the method is the use of soluble organometallic catalyst, such as an organopalladium catalyst. Preferably, soluble tetrakistriphenylphosphine palladium (0) is used. The allyl deprotection method now disclosed is suitable for use on an instrument for automated peptide synthesis. Methods of preparing the soluble organometallic catalyst are also disclosed, as are soluble catalyst compositions.
    Type: Grant
    Filed: September 20, 1996
    Date of Patent: January 19, 1999
    Assignee: PerSeptive Biosystems, Inc.
    Inventors: Fernando Albericio, Steven A. Kates
  • Automated allyl deprotection in solid-phase synthesis
    Patent number: 5777077
    Abstract: A method for removing an allyl protecting group from an allyl-protected derivative of a biologically relevant amino acid is disclosed. One relevant aspect of the method is the use of soluble organometallic catalyst, such as an organopalladium catalyst. Preferably, soluble tetrakistriphenylphosphine palladium (0) is used. The allyl deprotection method now disclosed is suitable for use on an instrument for automated peptide synthesis. Methods of preparing the soluble organometallic catalyst are also disclosed, as are soluble catalyst compositions.
    Type: Grant
    Filed: February 20, 1997
    Date of Patent: July 7, 1998
    Assignee: PerSeptive Biosystems, Inc.
    Inventors: Fernando Albericio, Steven A. Kates
  • Polyethylene glycol derivatives for solid-phase applications
    Patent number: 5545698
    Abstract: The present invention pertains to polyethylene glycol (PEG) derivatized graft supports, to methods for making these supports and to methods of using the supports to synthesize peptides by solid-phase synthesis techniques. The PEG-graft supports of this invention comprise functionalized PEG derivatives which are covalently attached to solid supports, such as polystyrene.
    Type: Grant
    Filed: November 10, 1993
    Date of Patent: August 13, 1996
    Assignee: University of Minnesota
    Inventors: George Barany, Fernando Albericio, Nuria A. Sol e, Jane Chang, Samuel Zalipsky
  • Polyethylene glycol derivatives for solid-phase applications
    Patent number: 5235028
    Abstract: The present invention pertains to polyethylene glycol (PEG) derivatized graft supports, to methods for making these supports and to methods of using the supports to synthesize peptides by solid-phase synthesis techniques. The PEG-graft supports of this invention comprise functionalized PEG derivatives which are covalently attached to solid supports, such as polystyrene.
    Type: Grant
    Filed: September 16, 1991
    Date of Patent: August 10, 1993
    Assignee: University of Minnesota
    Inventors: George Barany, Fernando Albericio, Jane Chang, Samuel Zalipsky, Nuria A. Sole
  • Hypersensitive acid-labile handle for solid-phase peptide synthesis
    Patent number: 5196566
    Abstract: Novel acid-labile tris(alkoxy)benzyl ester handles for use in linking protected amino acid or peptides to a support during peptide synthesis are disclosed. Methods for producing the handles, for linking them to solid support resins and for using the resin-linked handles in peptide synthesis are disclosed.
    Type: Grant
    Filed: August 31, 1990
    Date of Patent: March 23, 1993
    Assignee: Regents of the University of Minnesota
    Inventors: George Barany, Fernando Albericio