Patents by Inventor Fernando Patolsky

Fernando Patolsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160204283
    Abstract: A photovoltaic cell device is disclosed. The device comprises: an active region having a plurality of spaced-apart elongated nanostructures aligned vertically with respect to an electrically conductive substrate, wherein each elongated nanostructure has at least one p-n junction characterized by a bandgap within the electromagnetic spectrum, and is coated by an electrically conductive layer being electrically isolated from the substrate.
    Type: Application
    Filed: August 11, 2014
    Publication date: July 14, 2016
    Inventors: Fernando PATOLSKY, Alon KOSLOFF
  • Patent number: 9304118
    Abstract: Devices, methods and systems for detecting nitro-containing compounds such as TNT, which utilize semiconductor nanostructures modified by a functional moiety that interacts with the nitro-containing compound, are disclosed. The functional moiety is attached to the nanostructures and is being such that upon contacting a sample that contains the nitro-containing compound, the nanostructure exhibits a detectable change in an electrical property, which is indicative of the presence and/or amount of the nitro-containing compound in the sample. Electronic noses for generating recognition patterns of various nitro-containing compounds, made of a plurality of nanostructures modified by versatile functional moieties are also disclosed. The devices, methods and systems are suitable for detecting nitro-containing compounds in both liquid and gaseous states and for detecting a concentration of a nitro-containing compound such as TNT as low as attomolar concentrations.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: April 5, 2016
    Assignee: Tracense Systems Ltd.
    Inventors: Fernando Patolsky, Yoni Engel, Roey Elnathan
  • Publication number: 20160033498
    Abstract: The present invention generally relates to nanotechnology and sub-microelectronic circuitry, as well as associated methods and devices, for example, nanoscale wire devices and methods for use in determining nucleic acids or other analytes suspected to be present in a sample (for example, their presence and/or dynamical information), e.g., at the single molecule level. For example, a nanoscale wire device can be used in some cases to detect single base mismatches within a nucleic acid (e.g., by determining association and/or dissociation rates). In one aspect, dynamical information such as a binding constant, an association rate, and/or a dissociation rate, can be determined between a nucleic acid or other analyte, and a binding partner immobilized relative to a nanoscale wire. In some cases, the nanoscale wire includes a first portion comprising a metal-semiconductor compound, and a second portion that does not include a metal-semiconductor compound.
    Type: Application
    Filed: June 30, 2015
    Publication date: February 4, 2016
    Applicant: President and Fellows of Harvard College
    Inventors: Charles M. Lieber, Ying Fang, Fernando Patolsky
  • Patent number: 9228991
    Abstract: The present invention discloses a method for determining the presence of a drug or drug mixture in a liquid medium such as a beverage.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: January 5, 2016
    Assignee: RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Fernando Patolsky, Michael Ioffe, Eli Flaxer
  • Publication number: 20150362474
    Abstract: Devices, methods and systems for detecting nitro-containing compounds such as TNT, which utilize semiconductor nanostructures modified by a functional moiety that interacts with the nitro-containing compound, are disclosed. The functional moiety is attached to the nanostructures and is being such that upon contacting a sample that contains the nitro-containing compound, the nanostructure exhibits a detectable change in an electrical property, which is indicative of the presence and/or amount of the nitro-containing compound in the sample. Electronic noses for generating recognition patterns of various nitro-containing compounds, made of a plurality of nanostructures modified by versatile functional moieties are also disclosed. The devices, methods and systems are suitable for detecting nitro-containing compounds in both liquid and gaseous states and for detecting a concentration of a nitro-containing compound such as TNT as low as attomolar concentrations.
    Type: Application
    Filed: June 10, 2015
    Publication date: December 17, 2015
    Applicant: Tracense Systems Ltd.
    Inventors: Fernando PATOLSKY, Yoni ENGEL, Roey ELNATHAN
  • Publication number: 20150316523
    Abstract: A method and a system for identifying an explosive in a sample are disclosed. The method comprises receiving an explosive fingerprint defined by a set of kinetic parameters, describing a plurality of interactions between the explosive and each of a respective plurality of functional moieties. The method further comprises using a data processor for accessing a database of explosive fingerprints, and searching the database for a database fingerprint matching the received fingerprint. The system comprises a plurality of sensing devices, each comprising semiconductor nanostructures (e.g. Si nanowires) having attached thereto a functional moiety selected to interact with a nitro-containing and/or peroxide-containing explosive sample.
    Type: Application
    Filed: January 20, 2014
    Publication date: November 5, 2015
    Applicant: Tracense Systems Ltd.
    Inventors: Fernando PATOLSKY, Ronen SHACHAM, Amir LICHTENSTEIN, Ehud HAVIVI, Ehud HAHAMY
  • Patent number: 9102521
    Abstract: The present invention generally relates to nanoscale wire devices and methods for use in determining nucleic acids or other analytes suspected to be present in a sample. For example, a nanoscale wire device can be used to detect single base mismatches within a nucleic acid (e.g., by determining association and/or dissociation rates). In one aspect, dynamical information such as a binding constant, an association rate, and/or a dissociation rate, can be determined between an analyte and a binding partner immobilized relative to a nanoscale wire. In some cases, the nanoscale wire includes a first portion comprising a metal-semiconductor compound, and a second portion that does not include a metal-semiconductor compound. The binding partner, in some embodiments, is immobilized relative to at least the second portion of the nanoscale wire, and the size of the second portion of the nanoscale wire may be minimized and/or controlled in some instances.
    Type: Grant
    Filed: June 11, 2007
    Date of Patent: August 11, 2015
    Assignee: President and Fellows of Harvard College
    Inventors: Charles M. Lieber, Ying Fang, Fernando Patolsky
  • Patent number: 9063053
    Abstract: Devices, methods and systems for detecting nitro-containing compounds such as TNT, which utilize semiconductor nanostructures modified by a functional moiety that interacts with the nitro-containing compound, are disclosed. The functional moiety is attached to the nanostructures and is being such that upon contacting a sample that contains the nitro-containing compound, the nanostructure exhibits a detectable change in an electrical property, which is indicative of the presence and/or amount of the nitro-containing compound in the sample. Electronic noses for generating recognition patterns of various nitro-containing compounds, made of a plurality of nanostructures modified by versatile functional moieties are also disclosed. The devices, methods and systems are suitable for detecting nitro-containing compounds in both liquid and gaseous states and for detecting a concentration of a nitro-containing compound such as TNT as low as attomolar concentrations.
    Type: Grant
    Filed: June 6, 2011
    Date of Patent: June 23, 2015
    Assignee: Tracense Systems Ltd.
    Inventors: Fernando Patolsky, Yoni Engel, Roey Elnathan
  • Publication number: 20140367834
    Abstract: A process of fabricating a nanostructure is disclosed. The process is effected by growing the nanostructure in situ within a trench formed in a substrate and having therein a metal catalyst selected for catalyzing the nanostructure growth, under the conditions in which the growth is guided by the trench. Also disclosed are nanostructure systems comprising a nanostructure, devices containing such systems and uses thereof.
    Type: Application
    Filed: January 1, 2012
    Publication date: December 18, 2014
    Applicant: Romot at Tel-Aviv University Ltd.
    Inventors: Fernando Patolsky, Alexander Pevzner, Yoni Engel, Roey Elnathan, Alexander Tsukernik, Zahava Barkay
  • Publication number: 20140255972
    Abstract: A method of measuring a metabolic activity (MA) of a cell is provided. The method comprising independently measuring in an extracellular environment of the cell, time-dependent acidification profiles due to secretion of: (i) non-volatile soluble metabolic products; (ii) non-volatile soluble metabolic products and volatile soluble metabolic products; and (iii) volatile soluble metabolic products; wherein at least one of the time dependent acidification profiles is indicative of the metabolic activity of the cell. Also provided are clinical methods which make use of the assay.
    Type: Application
    Filed: May 18, 2014
    Publication date: September 11, 2014
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Reuven TIROSH, Fernando Patolsky, Hagit Peretz-Soroka
  • Patent number: 8728758
    Abstract: A method of measuring a metabolic activity (MA) of a cell is provided. The method comprising independently measuring in an extracellular environment of the cell, time-dependent acidification profiles due to secretion of: (i) non-volatile soluble metabolic products; (ii) non-volatile soluble metabolic products and volatile soluble metabolic products; and (iii) volatile soluble metabolic products; wherein at least one of the time dependent acidification profiles is indicative of the metabolic activity of the cell. Also provided are clinical methods which make use of the assay.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: May 20, 2014
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Reuven Tirosh, Fernando Patolsky, Hagit Peretz-Soroka
  • Patent number: 8632873
    Abstract: An elongated nanostructure is formed on a planar surface of a substrate such that the nanostructure is oriented generally perpendicularly to the surface. The nanostructure is then felled onto the surface such that it is oriented generally parallel to the surface.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: January 21, 2014
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Fernando Patolsky, Tamir Ducobni, Alexander Pevzner, Yoni Engel, Roey Elnathan, Moshit Ben-Ishai
  • Publication number: 20130329216
    Abstract: The present invention discloses a method for determining the presence of a drug or drug mixture in a liquid medium such as a beverage.
    Type: Application
    Filed: December 6, 2011
    Publication date: December 12, 2013
    Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Fernando Patolsky, Michael Ioffe, Eli Flaxer
  • Publication number: 20130230747
    Abstract: A fuel cell system comprising an anode compartment which comprises an anode having a copper catalyst layer, a cathode configured as an air cathode and a separator interposed between said anode and said cathode, operable by an amine-derived fuel and oxygen (or air) is disclosed. Further disclosed are fuel cell systems comprising an anode compartment which comprises an anode having a copper catalyst layer, a cathode and a separator interposed between said anode and said cathode, which are operable by a mixture of two types of amine-derived compounds (e.g., ammonia borane, hydrazine and derivatives thereof). Also disclosed are methods of producing electric energy by, and electric-consuming devices containing and operable by, the disclosed fuel cell systems.
    Type: Application
    Filed: October 11, 2011
    Publication date: September 5, 2013
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Fernando Patolsky, Boris Filanovsky, Eran Granot, Igor Presman, Ilia Kuras, Ricardo Osiroff, Opher Shapira
  • Publication number: 20130224789
    Abstract: A method of measuring a metabolic activity (MA) of a cell is provided. The method comprising independently measuring in an extracellular environment of the cell, time-dependent acidification profiles due to secretion of: (i) non-volatile soluble metabolic products; (ii) non-volatile soluble metabolic products and volatile soluble metabolic products; and (iii) volatile soluble metabolic products; wherein at least one of the time dependent acidification profiles is indicative of the metabolic activity of the cell. Also provided are clinical methods which make use of the assay.
    Type: Application
    Filed: April 4, 2012
    Publication date: August 29, 2013
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Reuven Tirosh, Fernando Patolsky, Hagit Peretz-Soroka
  • Patent number: 8475968
    Abstract: A fueled cell system comprising: an anode compartment comprising a compound having the formula R1R2N—NR3R4, a salt, a hydrate or a solvate thereof, as fuel, and a catalyst layer which comprises copper or a copper alloy; a cathode compartment comprising an oxidant; and a separator interposed between said cathode and said anode compartments, wherein each of R1-R4 is independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, heteroalicyclic, alkoxy, carboxy, ketone, amide, hydrazide and amine, provided that at least one of R1-R4 is hydrogen.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: July 2, 2013
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Fernando Patolsky, Boris Filanovsky, Eran Granot
  • Publication number: 20130115705
    Abstract: Devices, methods and systems for detecting nitro-containing compounds such as TNT, which utilize semiconductor nanostructures modified by a functional moiety that interacts with the nitro-containing compound, are disclosed. The functional moiety is attached to the nanostructures and is being such that upon contacting a sample that contains the nitro-containing compound, the nanostructure exhibits a detectable change in an electrical property, which is indicative of the presence and/or amount of the nitro-containing compound in the sample. Electronic noses for generating recognition patterns of various nitro-containing compounds, comprising a plurality of nanostructures modified by versatile functional moieties are also disclosed. The devices, methods and systems are suitable for detecting nitro-containing compounds in both liquid and gaseous states and for detecting a concentration of a nitro-containing compound such as TNT as low as attomolar concentrations.
    Type: Application
    Filed: June 6, 2011
    Publication date: May 9, 2013
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Fernando Patolsky, Yoni Engel, Roey Elnathan
  • Patent number: 8232584
    Abstract: Various aspects of the invention relate to nanoscale wire devices and methods of use for detecting analytes. In one aspect, the invention relates to a nanoscale electrical sensor array device, comprising at least one n-doped semiconductor nanoscale wire and at least one p-doped semiconductor nanoscale wire, each having a reaction entity immobilized thereon. Binding of an analyte to the immobilized reaction entity causes a detectable change in the electrical property of the nanoscale wire. In some embodiments, the reaction entity can be a nucleic acid that may interact with other nucleic acids, proteins, etc. In a specific embodiment, the nucleic acid may interact with an enzyme such as telomerase, which can extend the nucleic acid. In other embodiments, the analyte to be detected can be a toxin, virus or small molecule. Systems and methods of using such nanoscale devices are also disclosed, for example, within a microarray.
    Type: Grant
    Filed: August 5, 2009
    Date of Patent: July 31, 2012
    Assignee: President and Fellows of Harvard College
    Inventors: Charles M. Lieber, Fernando Patolsky, Gengfeng Zheng
  • Publication number: 20120167962
    Abstract: A method of fabricating a film. The method comprises directing onto a substrate a pulsed supersonic beam of a molecular precursor characterized by kinetic energy of at least 1 eV per molecule, such that non-volatile species of molecules of the precursor are deposited on the substrate.
    Type: Application
    Filed: June 30, 2010
    Publication date: July 5, 2012
    Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Uzi Even, Nachum Lavie, Fernando Patolsky
  • Publication number: 20120148799
    Abstract: An elongated nanostructure is formed on a planar surface of a substrate such that the nanostructure is oriented generally perpendicularly to the surface. The nanostructure is then felled onto the surface such that it is oriented generally parallel to the surface.
    Type: Application
    Filed: August 11, 2010
    Publication date: June 14, 2012
    Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Fernando Patolsky, Tamir Ducobni, Alexander Pevzner, Yoni Engel, Roey Elnathan, Moshit Ben-Ishai