Patents by Inventor Fernando Patolsky
Fernando Patolsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160204283Abstract: A photovoltaic cell device is disclosed. The device comprises: an active region having a plurality of spaced-apart elongated nanostructures aligned vertically with respect to an electrically conductive substrate, wherein each elongated nanostructure has at least one p-n junction characterized by a bandgap within the electromagnetic spectrum, and is coated by an electrically conductive layer being electrically isolated from the substrate.Type: ApplicationFiled: August 11, 2014Publication date: July 14, 2016Inventors: Fernando PATOLSKY, Alon KOSLOFF
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Patent number: 9304118Abstract: Devices, methods and systems for detecting nitro-containing compounds such as TNT, which utilize semiconductor nanostructures modified by a functional moiety that interacts with the nitro-containing compound, are disclosed. The functional moiety is attached to the nanostructures and is being such that upon contacting a sample that contains the nitro-containing compound, the nanostructure exhibits a detectable change in an electrical property, which is indicative of the presence and/or amount of the nitro-containing compound in the sample. Electronic noses for generating recognition patterns of various nitro-containing compounds, made of a plurality of nanostructures modified by versatile functional moieties are also disclosed. The devices, methods and systems are suitable for detecting nitro-containing compounds in both liquid and gaseous states and for detecting a concentration of a nitro-containing compound such as TNT as low as attomolar concentrations.Type: GrantFiled: June 10, 2015Date of Patent: April 5, 2016Assignee: Tracense Systems Ltd.Inventors: Fernando Patolsky, Yoni Engel, Roey Elnathan
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Publication number: 20160033498Abstract: The present invention generally relates to nanotechnology and sub-microelectronic circuitry, as well as associated methods and devices, for example, nanoscale wire devices and methods for use in determining nucleic acids or other analytes suspected to be present in a sample (for example, their presence and/or dynamical information), e.g., at the single molecule level. For example, a nanoscale wire device can be used in some cases to detect single base mismatches within a nucleic acid (e.g., by determining association and/or dissociation rates). In one aspect, dynamical information such as a binding constant, an association rate, and/or a dissociation rate, can be determined between a nucleic acid or other analyte, and a binding partner immobilized relative to a nanoscale wire. In some cases, the nanoscale wire includes a first portion comprising a metal-semiconductor compound, and a second portion that does not include a metal-semiconductor compound.Type: ApplicationFiled: June 30, 2015Publication date: February 4, 2016Applicant: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Ying Fang, Fernando Patolsky
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Patent number: 9228991Abstract: The present invention discloses a method for determining the presence of a drug or drug mixture in a liquid medium such as a beverage.Type: GrantFiled: December 6, 2011Date of Patent: January 5, 2016Assignee: RAMOT AT TEL-AVIV UNIVERSITY LTD.Inventors: Fernando Patolsky, Michael Ioffe, Eli Flaxer
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Publication number: 20150362474Abstract: Devices, methods and systems for detecting nitro-containing compounds such as TNT, which utilize semiconductor nanostructures modified by a functional moiety that interacts with the nitro-containing compound, are disclosed. The functional moiety is attached to the nanostructures and is being such that upon contacting a sample that contains the nitro-containing compound, the nanostructure exhibits a detectable change in an electrical property, which is indicative of the presence and/or amount of the nitro-containing compound in the sample. Electronic noses for generating recognition patterns of various nitro-containing compounds, made of a plurality of nanostructures modified by versatile functional moieties are also disclosed. The devices, methods and systems are suitable for detecting nitro-containing compounds in both liquid and gaseous states and for detecting a concentration of a nitro-containing compound such as TNT as low as attomolar concentrations.Type: ApplicationFiled: June 10, 2015Publication date: December 17, 2015Applicant: Tracense Systems Ltd.Inventors: Fernando PATOLSKY, Yoni ENGEL, Roey ELNATHAN
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Publication number: 20150316523Abstract: A method and a system for identifying an explosive in a sample are disclosed. The method comprises receiving an explosive fingerprint defined by a set of kinetic parameters, describing a plurality of interactions between the explosive and each of a respective plurality of functional moieties. The method further comprises using a data processor for accessing a database of explosive fingerprints, and searching the database for a database fingerprint matching the received fingerprint. The system comprises a plurality of sensing devices, each comprising semiconductor nanostructures (e.g. Si nanowires) having attached thereto a functional moiety selected to interact with a nitro-containing and/or peroxide-containing explosive sample.Type: ApplicationFiled: January 20, 2014Publication date: November 5, 2015Applicant: Tracense Systems Ltd.Inventors: Fernando PATOLSKY, Ronen SHACHAM, Amir LICHTENSTEIN, Ehud HAVIVI, Ehud HAHAMY
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Patent number: 9102521Abstract: The present invention generally relates to nanoscale wire devices and methods for use in determining nucleic acids or other analytes suspected to be present in a sample. For example, a nanoscale wire device can be used to detect single base mismatches within a nucleic acid (e.g., by determining association and/or dissociation rates). In one aspect, dynamical information such as a binding constant, an association rate, and/or a dissociation rate, can be determined between an analyte and a binding partner immobilized relative to a nanoscale wire. In some cases, the nanoscale wire includes a first portion comprising a metal-semiconductor compound, and a second portion that does not include a metal-semiconductor compound. The binding partner, in some embodiments, is immobilized relative to at least the second portion of the nanoscale wire, and the size of the second portion of the nanoscale wire may be minimized and/or controlled in some instances.Type: GrantFiled: June 11, 2007Date of Patent: August 11, 2015Assignee: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Ying Fang, Fernando Patolsky
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Patent number: 9063053Abstract: Devices, methods and systems for detecting nitro-containing compounds such as TNT, which utilize semiconductor nanostructures modified by a functional moiety that interacts with the nitro-containing compound, are disclosed. The functional moiety is attached to the nanostructures and is being such that upon contacting a sample that contains the nitro-containing compound, the nanostructure exhibits a detectable change in an electrical property, which is indicative of the presence and/or amount of the nitro-containing compound in the sample. Electronic noses for generating recognition patterns of various nitro-containing compounds, made of a plurality of nanostructures modified by versatile functional moieties are also disclosed. The devices, methods and systems are suitable for detecting nitro-containing compounds in both liquid and gaseous states and for detecting a concentration of a nitro-containing compound such as TNT as low as attomolar concentrations.Type: GrantFiled: June 6, 2011Date of Patent: June 23, 2015Assignee: Tracense Systems Ltd.Inventors: Fernando Patolsky, Yoni Engel, Roey Elnathan
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Publication number: 20140367834Abstract: A process of fabricating a nanostructure is disclosed. The process is effected by growing the nanostructure in situ within a trench formed in a substrate and having therein a metal catalyst selected for catalyzing the nanostructure growth, under the conditions in which the growth is guided by the trench. Also disclosed are nanostructure systems comprising a nanostructure, devices containing such systems and uses thereof.Type: ApplicationFiled: January 1, 2012Publication date: December 18, 2014Applicant: Romot at Tel-Aviv University Ltd.Inventors: Fernando Patolsky, Alexander Pevzner, Yoni Engel, Roey Elnathan, Alexander Tsukernik, Zahava Barkay
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Publication number: 20140255972Abstract: A method of measuring a metabolic activity (MA) of a cell is provided. The method comprising independently measuring in an extracellular environment of the cell, time-dependent acidification profiles due to secretion of: (i) non-volatile soluble metabolic products; (ii) non-volatile soluble metabolic products and volatile soluble metabolic products; and (iii) volatile soluble metabolic products; wherein at least one of the time dependent acidification profiles is indicative of the metabolic activity of the cell. Also provided are clinical methods which make use of the assay.Type: ApplicationFiled: May 18, 2014Publication date: September 11, 2014Applicant: Ramot at Tel-Aviv University Ltd.Inventors: Reuven TIROSH, Fernando Patolsky, Hagit Peretz-Soroka
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Patent number: 8728758Abstract: A method of measuring a metabolic activity (MA) of a cell is provided. The method comprising independently measuring in an extracellular environment of the cell, time-dependent acidification profiles due to secretion of: (i) non-volatile soluble metabolic products; (ii) non-volatile soluble metabolic products and volatile soluble metabolic products; and (iii) volatile soluble metabolic products; wherein at least one of the time dependent acidification profiles is indicative of the metabolic activity of the cell. Also provided are clinical methods which make use of the assay.Type: GrantFiled: April 4, 2012Date of Patent: May 20, 2014Assignee: Ramot at Tel-Aviv University Ltd.Inventors: Reuven Tirosh, Fernando Patolsky, Hagit Peretz-Soroka
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Patent number: 8632873Abstract: An elongated nanostructure is formed on a planar surface of a substrate such that the nanostructure is oriented generally perpendicularly to the surface. The nanostructure is then felled onto the surface such that it is oriented generally parallel to the surface.Type: GrantFiled: August 11, 2010Date of Patent: January 21, 2014Assignee: Ramot at Tel-Aviv University Ltd.Inventors: Fernando Patolsky, Tamir Ducobni, Alexander Pevzner, Yoni Engel, Roey Elnathan, Moshit Ben-Ishai
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Publication number: 20130329216Abstract: The present invention discloses a method for determining the presence of a drug or drug mixture in a liquid medium such as a beverage.Type: ApplicationFiled: December 6, 2011Publication date: December 12, 2013Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.Inventors: Fernando Patolsky, Michael Ioffe, Eli Flaxer
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Publication number: 20130230747Abstract: A fuel cell system comprising an anode compartment which comprises an anode having a copper catalyst layer, a cathode configured as an air cathode and a separator interposed between said anode and said cathode, operable by an amine-derived fuel and oxygen (or air) is disclosed. Further disclosed are fuel cell systems comprising an anode compartment which comprises an anode having a copper catalyst layer, a cathode and a separator interposed between said anode and said cathode, which are operable by a mixture of two types of amine-derived compounds (e.g., ammonia borane, hydrazine and derivatives thereof). Also disclosed are methods of producing electric energy by, and electric-consuming devices containing and operable by, the disclosed fuel cell systems.Type: ApplicationFiled: October 11, 2011Publication date: September 5, 2013Applicant: Ramot at Tel-Aviv University Ltd.Inventors: Fernando Patolsky, Boris Filanovsky, Eran Granot, Igor Presman, Ilia Kuras, Ricardo Osiroff, Opher Shapira
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Publication number: 20130224789Abstract: A method of measuring a metabolic activity (MA) of a cell is provided. The method comprising independently measuring in an extracellular environment of the cell, time-dependent acidification profiles due to secretion of: (i) non-volatile soluble metabolic products; (ii) non-volatile soluble metabolic products and volatile soluble metabolic products; and (iii) volatile soluble metabolic products; wherein at least one of the time dependent acidification profiles is indicative of the metabolic activity of the cell. Also provided are clinical methods which make use of the assay.Type: ApplicationFiled: April 4, 2012Publication date: August 29, 2013Applicant: Ramot at Tel-Aviv University Ltd.Inventors: Reuven Tirosh, Fernando Patolsky, Hagit Peretz-Soroka
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Patent number: 8475968Abstract: A fueled cell system comprising: an anode compartment comprising a compound having the formula R1R2N—NR3R4, a salt, a hydrate or a solvate thereof, as fuel, and a catalyst layer which comprises copper or a copper alloy; a cathode compartment comprising an oxidant; and a separator interposed between said cathode and said anode compartments, wherein each of R1-R4 is independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, heteroalicyclic, alkoxy, carboxy, ketone, amide, hydrazide and amine, provided that at least one of R1-R4 is hydrogen.Type: GrantFiled: November 12, 2009Date of Patent: July 2, 2013Assignee: Ramot at Tel-Aviv University Ltd.Inventors: Fernando Patolsky, Boris Filanovsky, Eran Granot
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Publication number: 20130115705Abstract: Devices, methods and systems for detecting nitro-containing compounds such as TNT, which utilize semiconductor nanostructures modified by a functional moiety that interacts with the nitro-containing compound, are disclosed. The functional moiety is attached to the nanostructures and is being such that upon contacting a sample that contains the nitro-containing compound, the nanostructure exhibits a detectable change in an electrical property, which is indicative of the presence and/or amount of the nitro-containing compound in the sample. Electronic noses for generating recognition patterns of various nitro-containing compounds, comprising a plurality of nanostructures modified by versatile functional moieties are also disclosed. The devices, methods and systems are suitable for detecting nitro-containing compounds in both liquid and gaseous states and for detecting a concentration of a nitro-containing compound such as TNT as low as attomolar concentrations.Type: ApplicationFiled: June 6, 2011Publication date: May 9, 2013Applicant: Ramot at Tel-Aviv University Ltd.Inventors: Fernando Patolsky, Yoni Engel, Roey Elnathan
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Patent number: 8232584Abstract: Various aspects of the invention relate to nanoscale wire devices and methods of use for detecting analytes. In one aspect, the invention relates to a nanoscale electrical sensor array device, comprising at least one n-doped semiconductor nanoscale wire and at least one p-doped semiconductor nanoscale wire, each having a reaction entity immobilized thereon. Binding of an analyte to the immobilized reaction entity causes a detectable change in the electrical property of the nanoscale wire. In some embodiments, the reaction entity can be a nucleic acid that may interact with other nucleic acids, proteins, etc. In a specific embodiment, the nucleic acid may interact with an enzyme such as telomerase, which can extend the nucleic acid. In other embodiments, the analyte to be detected can be a toxin, virus or small molecule. Systems and methods of using such nanoscale devices are also disclosed, for example, within a microarray.Type: GrantFiled: August 5, 2009Date of Patent: July 31, 2012Assignee: President and Fellows of Harvard CollegeInventors: Charles M. Lieber, Fernando Patolsky, Gengfeng Zheng
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Publication number: 20120167962Abstract: A method of fabricating a film. The method comprises directing onto a substrate a pulsed supersonic beam of a molecular precursor characterized by kinetic energy of at least 1 eV per molecule, such that non-volatile species of molecules of the precursor are deposited on the substrate.Type: ApplicationFiled: June 30, 2010Publication date: July 5, 2012Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.Inventors: Uzi Even, Nachum Lavie, Fernando Patolsky
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Publication number: 20120148799Abstract: An elongated nanostructure is formed on a planar surface of a substrate such that the nanostructure is oriented generally perpendicularly to the surface. The nanostructure is then felled onto the surface such that it is oriented generally parallel to the surface.Type: ApplicationFiled: August 11, 2010Publication date: June 14, 2012Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.Inventors: Fernando Patolsky, Tamir Ducobni, Alexander Pevzner, Yoni Engel, Roey Elnathan, Moshit Ben-Ishai